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zyvox antibiotic coverage

Learn about side effects, interactions and indications. Skin infections, pneumonia, infections that are resistant to other antibiotics, and other bacterial infections are all treated by Zyvox.

Other names for this medication:
Linezolid, Zyvox

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Children 11 years of age and younger usually receive Zyvox injections 2 to 3 times daily, for 10 to 28 days. Zyvox is typically administered twice or three times daily (every 8 to 12 hours) to children 11 years of age and younger for 10 to 28 days. Zyvox liquid should not be shaken. Never miss a dose of Zyvox. Do not stop taking Zyvox before your doctor recommends, even if you are feeling better. Never measure with a typical household spoon. Measure the oral liquid precisely using an oral syringe, a measuring spoon, or a medicine cup. Skip the missed dose and resume regular dosing if it is almost time for your next dose. Take the missed dose as soon as you remember it if you miss it. However, your doctor might decide that you can learn to administer your own injections. Typically, injections are administered by a healthcare professional in a medical setting. For 10 to 28 days, it is typically taken twice daily (every 12 hours). Take Zyvox exactly as prescribed. You can take the capsules and oral liquid with or without food. The infusion typically lasts between 30 minutes and 2 hours. Your infection's type and severity will determine how long it takes to treat you. After 21 days, discard any leftover oral liquid. Zyvox comes as a capsule, an oral liquid, and in an IV injection form. Adults receive Zyvox injection twice daily for 10 to 28 days. Zyvox oral liquid Shake the bottle of oral liquid gently three to five times.


Comprehensive instructions on Zyvox dosage Do not use two doses at one time. If it is almost time for your next dose, skip the missed dose and use the medication as soon as you can.

Missed dose

To catch up, do not double the dose. Skip the missed dose if it is almost time for the subsequent dose. If you forget to take a dose, do so right away. At the appointed time, take your next dose.


Call the Poison Help hotline at 1-800-222-1222 or go to the emergency room.


Consult your pharmacist or the neighborhood waste management company. Unless specifically instructed to do so, avoid flushing medications down the toilet or pouring them into drains. Store away from bathrooms. Pets and children should not have access to any medications. Properly discard this product when it is expired or no longer needed. Store at room temperature away from light and moisture.

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Side effects

Rarely does this medication cause an extremely severe allergic reaction. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms. Diarrhea, headache, nausea, vomiting, or dizziness may occur. Severe headache, fast/slow/irregular/pounding heartbeat, chest pain, neck stiffness/soreness, severe nausea/vomiting, sweating/clammy skin (sometimes with fever), widened pupils, vision changes (such as double/blurred vision), and sudden sensitivity to light (photophobia) are all serious side effects that require immediate medical attention. If any of the following symptoms appear: rapid heartbeat, hallucinations, loss of coordination, extreme dizziness, unexplained fever, severe nausea/vomiting/diarrhea, twitching muscles, or unusual agitation/restlessness, seek medical attention right away. If you experience any very serious side effects, such as muscle rigidity, increased sweating, vision changes (such as blurred vision, change in color vision, loss of vision), mental/mood changes (such as agitation, confusion), or seizure, seek medical attention right away. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Inform your doctor or pharmacist as soon as possible if any of these side effects persist or get worse. If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor or pharmacist if you experience any additional side effects not covered above. For medical guidance on side effects in Canada, contact your doctor. For medical advice about side effects in the US, contact your doctor. This risk can be increased by a number of drug and food interactions (see the sections on how to use and drug interactions). Several users report no significant side effects from this medication. You should keep in mind that your doctor prescribed this medication because she or he thought it would benefit you more than it would harm you. Diarrhea that doesn't stop, stomach or abdominal pain or cramping, or blood or mucus in your stool should all be reported to your doctor right away. If you experience any severe side effects, such as deep or rapid breathing, unusual drowsiness, nausea or vomiting that won't stop, numbness or tingling in your hands or feet, unusual fatigue, or easy bleeding or bruising, contact your doctor right away. Tell your doctor or pharmacist about all the medications you take if you also use other medications that raise serotonin levels because the risk increases. This condition could develop during treatment or several weeks to months after it has ended. Rarely, this medication may cause a hypertensive crisis, a potentially fatal attack of extremely high blood pressure. The side effects listed here are not all possible side effects. A very serious condition known as serotonin syndrome/toxicity, which is caused infrequently by this medication, may increase serotonin levels. This medication may rarely cause a severe intestinal condition due to a bacteria called C. difficile. You can contact the FDA to report side effects by calling 1-800-FDA-1088 or visiting You can contact Health Canada at 1-866-234-2345 to report side effects.


Also tell them if you have taken fluoxetine within 5 weeks before starting linezolid. Find out from your doctor how long you should wait before taking linezolid after starting or stopping any of these medications. Ask your doctor when to start or stop taking this medication. Report the use of medications, such as herbal remedies (such as ephedra/ma huang), allergy and cold remedies (including decongestants like phenylephrine/pseudoephedrine), and stimulants (such as amphetamines, ephedrine, and epinephrine) before taking linezolid. Without your doctor's permission, you should never start, stop, or modify the dosage of any medications. During treatment with this medication, avoid using any other MAO inhibitors, including isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine. Your risk of experiencing serious side effects may increase or your medication's effectiveness may change due to drug interactions. Examples include illegal substances like MDMA/"ecstasy," St. John's wort, some antidepressants, such as mirtazapine, SSRIs like fluoxetine/paroxetine, and SNRIs like duloxetine/venlafaxine, tramadol, and some "triptans" used to treat migraines, like rizatriptan, sumatriptan, and zolmitriptan, among others. Keep a list of everything you use and give it to your doctor and pharmacist. This list should include both prescription and over-the-counter medications as well as herbal products. None of these drugs should be taken with linezolid. For two weeks prior to and following treatment with this medication, most MAO inhibitors should also be avoided. Also, see the section on how to use. If you use certain products with linezolid, or even if you use them weeks before or after taking linezolid, there may be an interaction. Some products that may interact with this drug include: diet pills/appetite suppressants (such as diethylpropion), drugs for attention deficit disorder (such as atomoxetine, methylphenidate), apraclonidine, bupropion, buspirone, carbamazepine, cyclobenzaprine, deutetrabenazine, a certain combination product (dextromethorphan/quinidine), levodopa, maprotiline, methyldopa, metoclopramide, certain opioid pain relievers (such as fentanyl, meperidine, methadone, tapentadol), certain drugs for Parkinson's disease (such as entacapone, tolcapone), certain supplements (such as tryptophan, tyramine), tetrabenazine, tricyclic antidepressants (such as amitriptyline, doxepin), valbenazine. A dangerous (possibly fatal) drug interaction could result from taking this medication along with other MAO inhibitors. Talk to your doctor or pharmacist for more details. In the two weeks before or after taking linezolid, let your doctor or pharmacist know if you use any of the items on the list of possible drug interactions or any of the items that boost serotonin. If you also take other medications that raise serotonin, your risk of developing serotonin syndrome or toxicity rises. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs. Not every possible drug interaction is covered in this document.


If you are taking an MAO inhibitor (see "Drug Interactions"), certain antidepressants, or have a history of allergies to any of Zyvox's ingredients, avoid taking it. You should also avoid taking it if your high blood pressure is uncontrolled. Phenylalanine consumption needs to be restricted if you have phenylketonuria. Zyvox has been associated with serious side effects, such as serotonin syndrome. Zyvox oral liquid contains phenylalanine. Lactic acidosis symptoms include nausea, vomiting, stomach pain, and fast breathing. Serotonin syndrome symptoms include agitation or restlessness confusion diarrhea fast heartbeat and high blood pressure hallucinations (seeing or hearing things that are not real) increased body temperature heavy sweating (without activity) shivering tremor loss of coordination nausea overactive reflexes rapid changes in blood pressure vomiting. Zyvox increases your risk of seizures, pseudomembranous colitis, la, seizures, and vision loss. Ask your doctor about the additional Zyvox formulations that are offered. A potentially fatal condition called this has been reported in some Zyvox recipients. If you take specific medications that lower serotonin levels or if you have carcinoid syndrome, you run a higher risk of developing this condition.

What is the drug Zyvox used for?

Linezolid is an antibiotic used to treat certain serious bacterial infections. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu).

Will Zyvox treat MRSA?

Zyvox is the only oral antibiotic approved by the Food and Drug Administration (FDA) for hard-to-treat resistant infections like MRSA.

Is Zyvox a vancomycin?

Zyvox (linezolid) and vancomycin are antibacterial drugs used to treat susceptible Gram-positive infections (for example, Staphylococcus). Vancomycin is also used to treat Clostridium difficile-associated diarrhea. Side effects of Zyvox and vancomycin that are similar include diarrhea, nausea, vomiting, and headache.

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Colin Lord Mar 14, 2011, 3:20:14 AM

A similar reaction may occur if buspirone is combined with linezolid (Zyvox), an antibiotic that is also an MAO inhibitor. The combination of buspirone and trazodone (Desyrel), an antidepressant, may cause abnormal liver enzymes in the blood. Busprione Buspirone may interact with drugs called monoamine oxidase (MAO) inhibitors -- such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane) -- which are used in psychiatric disorders. The use of buspirone with these drugs can cause increased blood pressure. Hydroxyzine Hydroxyzine adds to (exaggerates) the sedating effects of alcohol and other drugs that can cause sedation such as the benzodiazepine class of anti-anxiety drugs.

Vishal Taj PM Sep 5, 2015, 2:20:09 PM

Both Percocet and hydrocodone have the potential for abuse and addiction. Hydrocodone, like other opioids, stimulates receptors on nerves in the brain to increase the threshold to pain and reduce the perception of pain. Hydrocodone side effects Lightheadedness Dizziness Sedation Nausea Vomiting Drowsiness Constipation Spasm of the ureter, which can lead to difficulty in urinating. Mental and physical dependence can occur, but are unlikely when used for short-term pain relief.

Thanhphong Tran Aug 27, 2012, 7:34:26 AM

On top of the $2.3 billion fine, Pfizer said it would take new charges of up to $33 million to resolve state civil consumer fraud allegations related to promotions of Geodon. Pfizer acquired Bextra in its 2003 purchase of Pharmacia Corp. Pfizer’s marketing team promoted Bextra for acute pain, surgical pain and other unapproved uses, while its salesforce promoted the drug directly to doctors for those unapproved uses and dosages, according to the U.S. Department of Justice. The world’s biggest drugmaker was slapped with the huge fines by the U.S. government after being deemed a repeat offender in pitching drugs to patients and doctors for unapproved uses. Pfizer said it will pay $503 million to resolve practices involving Bextra, $301 million related to its schizophrenia drug Geodon, $98 million for Zyvox and about $50 million for its blockbuster Lyrica used to treat nerve pain and seizures. The company in January said it took a $2.3 billion charge late last year to resolve allegations involving Bextra and other drugs, but did not provide details at the time.

user8780653 Oct 10, 2016, 11:25:55 PM

This medicine is taken by mouth to relieve coughs due to common colds or other chest infections. Some side effects may go away as your body adjusts to the medicine. Using these products together might cause harmful side effects.

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