Zetia lowers cholesterol. Zetia should be used in conjunction with dietary, weight-loss, and exercise changes in lifestyle.
Other names for this medication:
Vytorin, Nexlizet, Ezetimibe, Ezetrol, Roszet
Similar Products:
Crestor, Gemfibrozil, Simvastatin, Atorvastatin, Lopid, Tricor, Fenofibrate, Zocor, Lipitor, Rosuvastatin
Continue to follow a cholesterol-lowering diet while taking Zetia. Zetia should only be taken once daily. Ask your doctor if you can take them simultaneously if you also take a medication to lower your cholesterol. If you forget to take Zetia , take it as soon as you remember. Regardless of whether you feel ill, it is crucial that you continue taking Zetia. If you take your medication at the same time every day, such as with breakfast, dinner, or at bedtime, it might be simpler to remember to do so. Unless your doctor instructs you otherwise, continue taking Zetia. To monitor your cholesterol level and look out for any side effects, visit your doctor frequently. Whether with food or not, take one dose of Zetia each day. Before you start taking Zetia along with a statin and throughout treatment, your doctor may perform blood tests to examine your liver.
For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to lower elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipid 10 years and older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, L Detailed Zetia dosage information Zetia dosage for homozygous familial hypercholesterolemia: Zetia dosage for hyperlipidemia in adults: Usual Adult Dose of Zetia for Sitosterolemia: Common dosage for children with homozygous familial hypercholesterolemia: Standard pediatric dosage for hyperlipidemia The typical pediatric dosage for sitosterolemia is:
Do not double the dose to catch up. Skip the missed dose if it is almost time for the next dose. If you forget to take a dose, take it as soon as you remember. Take your subsequent dose at the scheduled time.
Call your local Poison Control Center right away if you take too much Zetia, or go to the hospital right away for emergency care.
Speak with your pharmacy or the neighborhood waste removal service. Unless specifically instructed to do so, avoid flushing medications down the toilet or pouring them into drains. Do not keep items in the bathroom. Away from children and pets, keep all medications. When the product has run its course or is no longer required, dispose of it properly. Place items in a dark, dry place at room temperature.
The following side effects have also been noted in general use: allergic reactions, including rash, hives, raised red rash, sometimes with target-shaped lesions, swelling of the face, lips, tongue, and/or throat that may make breathing or swallowing difficult, joint pain, muscle aches, changes in some laboratory blood tests, liver issues, stomach pain, inflammation of the pancreas, nausea, dizziness, and tingling sensations. These reactions may require immediate treatment. If you experience unexplained muscle pain, tenderness, or weakness while taking Zetia, contact your doctor immediately. Patients who took Zetia in clinical studies reported few side effects. When Zetia was combined with a statin medication, patients have frequently experienced severe muscle problems while taking the medication. These symptoms included diarrhoea, joint pain, upper respiratory infection, and fatigue. You must act quickly because, in very rare cases, these muscle issues can be serious, with muscle breakdown leading to kidney damage.
Take Zetia 2 hours prior to or 4 hours following the administration of cholestyramine, colestipol, or colesevelam if you are also taking other cholesterol medication. Not all possible drug interactions are covered in this list. Other drugs may interact with ezetimibe, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor of all other medications you are taking, especially: This list is not complete. drugs that interact with zetia (more information) cyclosporine, fenofibric acid, gemfibrozil, or a blood thinner like warfarin, Coumadin, or Jantoven.
If you have a reaction to any of the ingredients in Zetia, avoid taking it. If you are a woman of childbearing age, you should use an efficient method of birth control to prevent pregnancy while taking Zetia in addition to statin therapy. Do not take Zetia while taking a statin if you are pregnant or nursing. Do not take Zetia while taking the cholesterol-lowering drug class statins if you have active liver disease. Zetia has not been studied in children under age 10.
Can Zetia (ezetimibe) cause liver damage?
Yes, Zetia (ezetimibe) can cause liver damage, although it is very rare. Monitor liver enzymes for the development of serious toxic hepatitis and consider ezetimibe discontinuation if it develops. Perform liver tests during ezetimibe initiation and regularly thereafter and consider withdrawal of ezetimibe and/or the statin (if coadministered) should an increase in ALT or AST ≥3 X upper limit of normal (ULN) persist.
Will Zetia make you gain weight?
Weight gain isn't a side effect reported in clinical studies of Zetia. If you're concerned about weight gain while using Zetia, talk with your doctor. They may suggest foods that can help lower your cholesterol and reduce your risk of weight gain.
Does Zetia (ezetimibe) cause memory loss?
Memory loss is not a side effect of Zetia (ezetimibe) when it is used alone to treat high cholesterol. Zetia is often used with diet and other cholesterol lowering medications like statins which have been linked with cognitive impairment (memory loss, forgetfulness, or confusion).
Is it a statin drug/medication?
No, Zetia is not a statin drug. Zetia reduces blood cholesterol in a different way to statin medications. Zetia lowers cholesterol levels by decreasing the amount of cholesterol that is absorbed from the small intestine, so that there is less intestinal cholesterol delivered to the liver.
Does Zetia (ezetimibe) cause memory loss?
Memory loss is not a side effect of Zetia (ezetimibe) when it is used alone to treat high cholesterol. Zetia is often used with diet and other cholesterol lowering medications like statins which have been linked with cognitive impairment (memory loss, forgetfulness, or confusion).
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Ezetimibe tablets, administered in combination with fenofibrate, are indicated as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, Apo B, and non-HDL-C in adult patients with mixed hyperlipidemia. Ezetimibe tablets work to reduce the amount of cholesterol the body absorbs. Ezetimibe tablets had annual sales of approximately $2.7 billion in the U.S., according to IMS data as of March 2017.
We believe the side effects of this drug differ from other statins because pitavastatin is water-soluble and metabolizes differently." Ezetimibe (Zetia), for example, is a drug that blocks the absorption of cholesterol and is a non-statin treatment option, but it only lowers bad cholesterol by 18 to 20 percent. The findings are important because up to 15 percent of the nation's heart patients can't tolerate other statin medications, currently the most effective cholesterol-lowering agents available.
This appears also to be a condition of the illegal reverse payment agreement. This is also the subject of several pending class actions, which have been consolidated in an MDL in the Eastern District of Virginia. Companies who paid all or part of the purchase price for Zetia, including on behalf of their insureds, from May 2010 through December 2016 should evaluate the size of their purchases and consider filing suit. The complaint alleges defendants violated the antitrust laws by entering into a “reverse payment” agreement in May 2010 whereby Glenmark agreed to drop its meritorious patent challenge against Merck in exchange for a payment from Merck and an agreement by Glenmark and Par not to launch a generic competitor to Zetia until December 12, 2016.
Despite new US cholesterol guidelines and a clinical trial that tamped down hopes that Merck’s cholesterol drug Zetia could make a difference in the rare disease space, an analysis of prescription trends found that the drug continues to plug along, earning almost $3 billion in sales in 2013. This change has led to speculation that while doctors may continue to prescribe statins, add-ons—like Merck’s Zetia and Vytorin—could wane. This study, called IMPROVE-IT, assesses Merck’s Vytorin, a combination drug that includes Zetia and simvistatin, and is set on determining if the drug is associated with a lower risk of CV death, major coronary events, and stroke. Meanwhile, Zetia’s patent has only two years left in the US. Researchers also found a higher use in one province: Saskatchewan, which has the drug on an unrestricted formulary level.
You should stick to a diet and exercise plan in addition to taking Zetia. Your doctor will monitor your liver function while you are taking Ezetimibe. Precautions It is not recommended that patients with liver dysfunction take Ezetimibe. Some of the side effects will go away as your body adjusts to Ezetimibe. Storage Store at room temperature (77 ºF).
Importantly, investigators aimed to treat patients to an LDL cholesterol target range of 25 to 50 mg/dL. “Scientifically, it’s a magnificent study. Speaking with the media, Steg stressed that he and his co-investigators are “not trying to spin a negative trial into a positive” with their LDL-cholesterol subgroup analysis.
How much money?—it’s the number one question we always get about settlements. Translation: you may be able to get some money back on your purchases as a result of this settlement. Well, as with all class action settlements, it first depends on the number of class members (in this case Vytorin and Zetia consumers during the class time period) who submit eligible claim forms—that’s because the $12,450,000 part of the settlement that has been earmarked for consumers will be shared among all consumers who file eligible claims.