Description

Ask your doctor or pharmacist for more information. Diclofenac is a prescription drug used to treat inflammation and pain associated with a number of conditions, including arthritis, migraines, sprains, and dysmenorrhea. It is also used treat actinic keratoses (AK). Because of prolonged sun exposure, this condition occurs when patches of skin become rough, dry, or scaly. Another purpose for this medication's prescription is possible.

Dosage

Assure that enough gel is applied to adequately cover each lesion. After therapy is stopped, it could take up to 30 days before the lesion(s) are fully healed or the best therapeutic effect becomes apparent. Do not use liquids other than water. Use it only as directed by your doctor, neither more nor less often. Tablet with an extended release The suggested daily dose for the treatment of osteoarthritis is 100 mg. Solutions for eye drops One drop should be rubbed into the affected eye four times per day beginning 24 hours after cataract surgery and continuing for the first two weeks following the procedure. For the relief of rheumatoid arthritis the recommended dosage is 150-200 mg/day in divided doses, 50 mg 3 or 4 times a day. The suggested dose is 100 mg once or twice a day for the treatment of rheumatoid arthritis. On the afflicted skin, it should be gently rubbed in. Each lesion site measuring 5 cm by 5 cm typically receives 0.5 grams of gel. Before having corneal refractive surgery, one or two drops should be placed in the affected eye. Oral: Capsule: The dosage is 18 mg or 35 mg orally three times a day. Patch: For 60 to 90 days, diclofenac gel should be applied twice daily to the skin. One packet of diclofenac (50 mg) should be mixed with 1 to 2 ounces (30 to 60 mL) of water and taken orally once daily, preferably without food. 100–150 mg/day in divided doses, or 50 mg twice or three times per day, is the recommended dosage for tablets used to treat osteoarthritis. The amount required is determined by the size of the lesion site. 60 to 90 days are the range for the suggested length of therapy. Topical liquid: 40 drops per knee, four times a day, is the recommended dose to relieve the signs and symptoms of osteoarthritis in the knee(s). Apply topical gel twice daily to lesion areas. Use exactly as prescribed. One or two drops should be applied to the surgical eye within 15 minutes of the procedure and should be repeated 4 times per day for up to 3 days.

Overdose

However, if overdose is thought to have occurred, get emergency medical help. An overdose is unlikely to happen if diclofenac is given in a medical setting by a healthcare professional. Call your doctor, your local poison control center, or get emergency medical help right away if you take too much diclofenac.

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Side effects

Ask your doctor or pharmacist for more information. For medical advice about side effects, contact your doctor. If any side effect bothers you or does not go away, let your doctor know right away. The following are some of the side effects of diclofenac that are most frequently reported: Topical: itching Redness irritation Rashes Dryness Scaling or Peeling This is not an exhaustive list of diclofenac side effects. Call the FDA at 1-800-FDA-1088 to report side effects.

Interactions

To learn more, consult your physician or pharmacist. Especially tell your doctor if you take: other NSAIDs such as aspirin, ibuprofen, or naproxen 'blood thinners' such as warfarin (Coumadin, Jantoven) voriconazole (Vfend) angiotensin-converting enzyme (ACE) blockers such as benazepril (Lotensin, Lotensin HCT) captopril (Capoten, Capozide) enalapril (Vasotec, Vaseretic) fosinopril (Monopril, Monopril HCT) lisinopril (Prinivil, Prinzide, Zestril, Zestoretic) moexipril (Univasc, Uniretic) quinapril (Accupril, Accuretic, Quinaretic) ramipril (Altace) trandolapril (Mavik, Tarka) diuretics such as acetazolamide (Diamox) amiloride (Midamor) bumetanide (Bumex) chlorothiazide (Diuril) chlorthalidone (Thalitone) ethacrynic acid (Edecrin) furosemide (Lasix) hydrochlorothiazide (Microzide, HCTZ) metolazone (Zaroxolyn) torsemide (Demadex) triamterene (Dyrenium, Dyazide, Maxzide) methotrexate (Trexall) lithium (Eskalith, Lithobid) cyclosporine (Gengraf, Neoral, Sandimmune) This is not a complete list of diclofenac drug interactions. Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Contraindications

Although some forms of diclofenac can be applied to the skin, some of the medication is absorbed into the blood stream. When taking diclofenac, blood pressure should be carefully monitored. Vertigo may be brought on by diclofenac. Diclofenac is an NSAID drug. Patients who are most at risk for this side effect, such as the elderly, those with impaired kidney function, heart failure, liver dysfunction, and those taking diuretics and ACE inhibitors, should use diclofenac with caution. Diclofenac should be used with caution in patients with fluid retention or heart failure. If rash or other skin reaction symptoms appear, stop taking diclofenac. Driving and using heavy equipment should not be done until you are aware of how diclofenac may affect you. Do not use diclofenac if you are allergic to diclofenac (the active ingredient), any inactive ingredient, or aspirin. Those who have taken NSAIDs have shown signs of fluid retention and swelling. Long-term use may result in kidney damage. NSAIDs have been linked to stomach and intestinal bleeding, ulcers, heart attack, stroke, congestive heart failure, allergic reactions, and worsening asthma. Patients with the aspirin triad or patients who had never taken diclofenac before have both experienced severe allergic reactions. Call 911 if you experience any of the following heart attack symptoms: chest discomfort (uncomfortable pressure, fullness, or pain in chest); shortness of breath Diclofenac can also cause or exacerbate preexisting hypertension. If you experience any of these symptoms, contact your doctor right away. Tell your doctor if you experience any of the following hypersensitivity symptoms or signs: chest pain swelling of the face, eyes, lips, tongue, arms, or legs difficulty breathing or swallowing rash Serious skin adverse events have been linked to the use of diclofenac.

Will it affect my fertility?

Taking anti-inflammatory medicines, like diclofenac, in large doses or for a long time can affect ovulation in women. This may make it more difficult to get pregnant. Do not take diclofenac if you're trying to get pregnant, or if you're having tests for infertility. Paracetamol is a better painkiller in these situations.

How does diclofenac work?

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. When you apply diclofenac gel, plasters or patches to your skin, it works in the same way as when you take it as a tablet or capsule. But the gel, plaster or patch only works on the area you have put it on.

Is Voltaren and Voltarol the same?

In the US, this drug is referred to as “Voltaren Arthritis Pain.” In the UK, this OTC drug is called “Voltarol.” Both Voltaren Arthritis Pain and Voltarol refer to similar topical products that contain forms of diclofenac as their active ingredient.

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