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alfuzosin vs tamsulosin

It works by relaxing the muscles in the prostate and bladder so that urine can flow easily. Alpha blockers are a group of drugs that includes tamsulosin. Men who have BPH, also known as benign prostatic hyperplasia, experience symptoms such as frequent and urgent urination, painful urination, and difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying). Tamsulosin is used to treat these symptoms.

Other names for this medication:
Flomax, Jalyn

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By blocking these adrenoceptors, smooth muscle in the prostate is relaxed and urinary flow is improved. Alpha-1A and alpha-1D adrenoceptors are blocked by tamsulosin. The alpha-1A subtype makes up about 70% of the alpha-1 adrenoceptors in the prostate. The alpha-1D adrenoceptors are blocked to relax the bladder's detrusor muscles and stop the symptoms of storage. Tamsulosin's specificity concentrates its effects on the intended area while minimizing its impact elsewhere.


Carefully adhere to the instructions on your prescription label. Tamsulosin should be taken at a dose of 0.4 mg once daily to treat the BPH (benign prostatic hyperplasia) signs and symptoms. Tamsulosin should be taken exactly as directed by your doctor. To get 0.8 mg of the medication, take 2 capsules once a day. Your doctor will determine the best dose for you.

Missed dose

Never take two doses at once to make up for missed ones. Skip the missed dose and carry on with your regular dosing schedule, though, if it is almost time for the subsequent dose. Call your doctor before starting the medication again if you stop taking it for a few days or longer, especially if you take more than one tamsulosin capsule per day. If you miss a dose, take it as soon as you remember.


Call 911 right away if the victim has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused. Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information is accessible online at Symptoms of overdose may include: dizziness fainting blurred vision upset stomach headache


You shouldn't flush this medication down the toilet, though. Instead, using a medication take-back program is the best way to get rid of your medication. As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Keep this medication out of the reach of children and tightly closed in the original container. If you are unable to participate in a take-back program, visit the FDA's Safe Disposal of Medicines website at for more details. Keep it at room temperature, away from sources of extreme heat, and dry (not in the bathroom). For information on take-back programs in your neighborhood, speak with your pharmacist or get in touch with the waste/recycling department of your city. Always lock safety caps and store medications up and away, out of sight, and away from young children to prevent poisoning. Unused medications should be disposed of in special ways to prevent pets, children, and other people from consuming them.

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Side effects

Call your doctor right away if you experience any of the following signs and symptoms: difficulty falling or staying asleep, sleepiness, weakness, back pain, diarrhea, runny or stuffy nose, pain or pressure in the face, fever, chills, or other indications of an infection, blurred vision, difficulty ejaculating, painful erections of the penis that last for hours, rash, itching, or hives, swelling of the arms, hands, feet, ankles, or lower legs Tamsulosin may cause side effects. Tell your doctor if any of these symptoms, along with those listed in the SPECIAL PRECAUTIONS section, are severe or do not go away: sleepiness difficulty falling asleep or staying asleep weakness back pain diarrhea runny or stuffy nose pain or pressure in the face blurred vision difficulty ejaculating painful erections of the penis that last for hours rash itching hives swelling of the eyes, face, tongue, lips, throat, arms, or legs.


For more information, consult your physician or pharmacist. Especially tell your doctor if you are taking: alfuzosin (Uroxatral) doxazosin (Cardura) prazosin (Minipress) terazosin (Hytrin) warfarin (Coumadin, Jantoven) cimetidine (Tagamet) sildenafil (Viagra) tadalafil (Cialis) vardenafil (Levitra) This is not a complete list of tamsulosin drug interactions. Inform your doctor about every medication you take, including vitamins, herbal supplements, prescription drugs, and over-the-counter medications.


Rashes, itching, and hives are some allergic reactions that can happen. Rarer and more severe allergic reactions can also happen. allergic reactions Until you are certain of how this medication will affect you, avoid operating machinery or driving a car. During cataract surgery, a condition called intraoperative floppy iris syndrome (IFIS) can happen if you take or have taken tamsulosin capsules. eye issues following cataract surgery. Get medical help right away if you have any of the following reactions: swelling of face, tongue, or throat difficulty breathing blistering of the skin A painful erection that will not go away. If priapism is not treated, you may not be able to get an erection in the future. Call your doctor if the symptoms are bothersome or do not go away. If this occurs, seek immediate medical attention. Sit or lie down until you feel better if you start to feel lightheaded. Tell your surgeon if you currently take or have ever taken tamsulosin capsules in the event that you require cataract surgery. While taking tamsulosin, let your doctor know if you experience any allergic reactions. Decreased blood pressure when changing positions is just one of the severe side effects that have happened. Change positions slowly from lying down to sitting up or from a sitting position to a standing position until you understand how you react to tamsulosin capsules. Symptoms may include fainting, dizziness, and lightheadedness. A painful erection (priapism) brought on by tamsulosin capsules may not be alleviated by sex. Particularly after the first dose or when switching doses, taking tamsulosin capsules may result in a sharp drop in blood pressure when standing up. You may feel lightheaded or sleepy after taking tamsulosin.

How long does it take for tamsulosin to work?

The effects of the drug can usually be felt within the first 48 hours. Complete urinary relief may take up to two to six weeks. If a 0.4-mg dose is unable to provide relief, your healthcare provider may recommend that you double the dose to 0.8 mg once daily.

Is there another drug like tamsulosin?

The selective agents, alfuzosin (Uroxatral), silodosin (Rapaflo), and tamsulosin (Flomax, generic), work primarily on the tissues of the urinary tract. The nonselective agents, doxazosin (Cardura, generic) and terazosin (Hytrin, generic), affect both the urinary tract and other tissues elsewhere in the body.

Will it affect my contraception?

Tamsulosin will not stop your contraception working, including the combined pill and emergency contraception.

How does it compare with other medicines for enlarged prostate?

There are a few other medicines that can help with symptoms associated with enlarged prostate. There are other alpha blockers such as alfuzosin, doxazosin and terazosin. Other medicines for enlarged prostate are 5-alpha-reductase inhibitors, also known as dihydrotestosterone inhibitors – for example finasteride and dutasteride. Some people may need to take a combination of an alpha blocker and a 5-alpha-reductase inhibitor if a single medicine is not helping their symptoms.

Can I drive or ride a bike?

Tamsulosin can make some people feel dizzy or lightheaded, especially when they first start taking it. If this happens to you, do not drive a car, ride a bike, or use tools or machinery. Wait until you feel OK again.

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apd May 22, 2017, 11:14:57 AM

Biotransformation: • Tamsulosin is extensively metabolized by cytochrome P450 enzymes in the liver, with < 10% of the dose excreted in the urine unchanged. Bioavailability is increased by 30% and peak concentration is increased by 40 to 70% when Tamsulosin is taken in the fasting state compared to the nonfasting state. Contraindications • Cataract Surgery, Intraoperative Floppy Iris Syndrome, Continued Painful Erection, Feeling Faint, Dizzy, Hypersensitivity to sulfonamide, severe hepatic impairment, lactation. Blockade of these adrenoceptors can cause smooth muscles in the bladder neck and prostate to relax, resulting in an improvement in urine flow rate and reduction in symptoms in BPH. Smooth muscle tone is mediated by the sympathetic nervous stimulation of α1A adrenoreceptors, which are abundant in the prostate, prostatic capsule, prostatic urethra, and bladder neck.

Ryan Lynch Jul 21, 2015, 11:53:49 AM

This study included 568 men with OAB who were treated with tamsulosin for LUTS. Patients in group 1 then received a placebo plus tamsulosin 0.2 mg and patients in group 2 received mirabegron 50 mg and tamsulosin 0.2 mg for 12 weeks. However, most of these were mild or moderate. The average number of urinations in 24 hours was the primary outcome measured.

user87060 Jan 13, 2021, 6:19:17 PM

Tamsulosin helps relax the muscles in the prostate and the opening of the bladder. As the prostate gland enlarges, certain muscles in the gland may become tight and get in the way of the tube that drains urine from the bladder. This medicine is available only with your doctor's prescription. Therefore, even though tamsulosin may lessen the problems caused by enlarged prostate now, surgery still may be needed in the future.

Donald Perrett May 8, 2021, 1:59:37 AM

People who have cataracts or glaucoma: Tamsulosin may affect the iris and make it “floppy” during ocular surgery, especially cataract surgery or glaucoma surgery. Chest pain (angina) Severe allergic reaction (hypersensitivity) with skin rash, swelling, trouble breathing, etc. If you have had a severe allergic reaction to sulfa in the past, use tamsulosin with caution. Do not crush, chew, or open the capsules. Seek medical advice from your healthcare provider or pharmacist for more information.

clelievre1977 Mar 30, 2017, 9:32:56 PM

Side Effects Headache Dizziness Rhinitis Infection Abnormal ejaculation Asthenia Back pain Diarrhea Somnolence Nausea For a full list of side effects that apply to you, do not hesitate to contact your pharmacist or doctor. Speak with your doctor or pharmacist to get more answers and information. Interactions Common medications that interact with Flomax are listed: Ketoconazole Erythromycin Paroxetine Terbinafine Sildenafil Warfarin For more information, do not hesitate to ask your doctor or pharmacist. Patients considering cataract surgery should tell their ophthalmologist that they have taken Flomax.

Savannah Potts Jul 23, 2010, 3:39:58 PM

A common side effect of taking this medication is: feeling dizzy – if you feel dizzy sit or lie down until you feel better If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. You may not be suitable for this medication if you: are about to have eye surgery are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine have kidney problems have liver problems have or have had a drop in blood pressure when standing or sitting up Everyone’s reaction to a medicine is different. • Tamsulosin hydrochloride is not suitable for everyone so it’s important that the person prescribing this medicine knows your full medical history. If you feel very ill, get medical help straight away.

Eric James Buglosa Dazo Oct 2, 2020, 10:47:40 PM

It is indicated for the treatment of moderate to severe storage symptoms (urgency, increased micturition frequency) and voiding symptoms associated with benign prostatic hyperplasia (BPH) in men who are not adequately responding to treatment with ... Astellas wish to announce that Vesomni, a fixed-dose combination (FDC) tablet containing the active ingredients solifenacin (antimuscarinic) plus tamsulosin (alpha-blocker), is now available in Ireland.

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