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Missing doses can make it harder to treat, so don't ever skip one. As part of a multi-drug approach to treating HIV infection, Sustiva is used.

Other names for this medication:
Stocrin, Symfi, Atripla, Efavirenz

Similar Products:
Kaletra, Daklinza, Lamivudine, Epivir, Harvoni, Truvada, Tenvir, Tenofovir, Ribavirin, Copegus, Ledipasvir, Ritonavir, Lopinavir, Daclatasvir, Sofosbuvir, Emtricitabine, Viraday


The human immunodeficiency virus (HIV) is prevented from proliferating in your body by the antiviral medication Sustiva. Sustiva is appropriate for use by both adults and children who are at least 3 months old and 8 pounds or more in weight. HIV, a virus that can lead to acquired immunodeficiency syndrome (AIDS), is treated with Sustiva. HIV or AIDS cannot be cured by this medication.


-Not endorsed by the US FDA. -Prophylaxis should be started as soon as possible, within 72 hours of exposure. For more information, it is advisable to consult the most recent therapeutic recommendations. The ideal prophylaxis duration is unknown and may vary depending on institution protocol. 3 months and older: 3.5 to less than 5 kg: 100 mg orally once a day; 7.5 to less than 15 kg: 200 mg orally once a day; 25 to less than 32.5 kg: 300 mg orally once a day; 32.5 to less than 40 kg: 400 mg orally once a day; and 40 kg or more: 600 mg orally once a day. 600 mg taken orally once daily Comments: -This medication needs to be used with NRTIs and/or a protease inhibitor. Detailed Sustiva dosage information US CDC recommendations: 600 mg orally once a day for 28 days of therapy Comments: -This medication should be used with (lamivudine or emtricitabine) plus (zidovudine or tenofovir); recommended as the preferred NNRTI-based regimen for non-occupational postexposure prophylaxis of HIV infection. Recommendations from the US Public Health Service working group: 600 mg orally once a day for 28 days, if tolerated Comments: -An alternative antiretroviral agent for use as HIV postexposure prophylaxis only with professional consultation -Prophylaxis should be started as soon as possible, preferably within hours after exposure. Use: For the treatment of HIV-1 infection in conjunction with other antiretroviral medications. The typical adult dose for HIV infection is: Standard Adult Dose for Non-Occupational Exposure The typical adult dose for occupational exposure Usual Pediatric Dose for HIV Infection:

Missed dose

Taking two doses at once is not advised. Get your prescriptions refilled before you run out of medicine completely. If it is almost time for your next dose, skip the missed dose and take the medication as soon as you remember.


However, if overdose is thought to have occurred, get emergency medical help. It is unlikely that an overdose will happen if Sustiva is given by a healthcare professional in a hospital setting. Call your doctor or the nearest poison control center right away if you take too much Sustiva, or go to the emergency room right away.

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Side effects

If you have: Call your doctor for medical advice about side effects. The following are possible side effects of Sustiva: If you experience any of these side effects, even if you have before, call your doctor right away. Your immune system is impacted by efavirenz, which may result in some side effects (even weeks or months after you've taken this medication). If you experience any of the following symptoms of an allergic reaction to Sustiva: hives, difficulty breathing, swelling of the face or throat, or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling), seek emergency medical attention. Confusion, a sense of sadness or hopelessness, suicidal thoughts, anxiety, paranoia, hallucinations, difficulty speaking or moving, and unusual behavior are just a few of the serious psychiatric symptoms that sutiva may bring on. The negative effects of Sustiva Inform your physician if you have: There may be additional side effects; this is not a comprehensive list. You can contact the FDA to report side effects at 1-800-FDA-1088. a seizure, hallucinations, difficulty concentrating, trouble speaking or moving (these symptoms may appear months or years after you begin taking efavirenz), nervous system issues such as dizziness, drowsiness, confusion, difficulty concentrating, strange dreams, insomnia, or issues with speech, balance, or muscle movement, severe psychiatric symptoms such as anxiety, paranoia, unusual behavior, feeling down or hopeless, hallucinations, or suicidal thoughts, or liver issues Changes in the shape or location of body fat, particularly in the arms, legs, face, neck, breasts, and waist, as well as nausea, vomiting, dizziness, drowsiness, trouble concentrating, rash, headache, and fatigue. Signs of a new infection include fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss, difficulty speaking or swallowing, issues with balance or eye movement, weakness or a prickly feeling, swelling in your neck or throat (enlarged thyroid), menstrual changes, and impotence.


Prescription and over-the-counter medications, vitamins, and herbal products, among others, may interact with efavirenz. Some medications can change the levels of other medications you take in your blood, which could increase side effects or reduce the effectiveness of the medication. Utilizing certain medications concurrently is occasionally not advised. A serious heart issue may result from taking sutiva. Sustiva drug interactions (detailed information) Inform your doctor about all of the medications you are taking now as well as any new or discontinued ones. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.


If you want to get pregnant, consult your doctor as well. Additionally, Sustiva may enter breast milk and seriously harm the infant. Do not breast-feed if you are taking Sustiva. If you are allergic to any of the inactive ingredients or the active ingredient, efavirenz, do not take Sustiva. Never take any additional medications without first consulting your doctor. Whether Sustiva was responsible for these flaws is unknown. John's wort (Hypericum perforatum). extended QTc. Some children's rashes could be a serious issue. Animals and pregnant women who took Sustiva have both experienced serious birth defects in their offspring. After treatment is stopped, sutiva may continue to circulate in your blood for some time. Sustiva may have more side effects, such as drowsiness, when combined with alcohol or other drugs that have similar side effects. If you are nursing a child, discuss this with your doctor. If you experience any side effects while your child is taking Sustiva, including rash, call your doctor right away. Tell your doctor right away if you are pregnant. The Centers for Disease Control and Prevention advise against breastfeeding for mothers who have HIV because the virus can be transmitted to the child through the mother's milk. As a result, you should keep using birth control for 12 weeks after stopping Sustiva. These medicines include prescription and nonprescription medicines and herbal products, especially St. Even if they also use other birth control options, women must use a reliable barrier method of contraception, such as a condom or diaphragm. Sustiva should not be used by women while they are trying to get pregnant or for 12 weeks after they stop. Women should not rely only on hormone-based birth control, such as pills, injections, or implants, because Sustiva may make these contraceptives ineffective. You may need to stop breast-feeding or use a different medicine. The other medications you are taking that could raise your risk for QTc prolongation will be evaluated by your doctor to determine whether any changes to them are necessary.

What is Sustiva used for?

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.

What class of drug is Sustiva?

Sustiva belongs to a class of drugs called HIV, NNRTIs.

Is there a generic for Sustiva?

Efavirenz tablets are the generic version of Sustiva ® from Bristol Myers Squibb and is used to treat HIV. Efavirenz tablets are available in 600mg 30ct bottle.

What class of drug is Sustiva?

Sustiva is an HIV medication. It is in a category of HIV medicines called non-nucleoside reverse transcriptase inhibitors.

What is Sustiva used for?

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.

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Moad Toutou Feb 14, 2018, 5:05:41 PM

Telaprevir (Incivek) is not combined with carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, and St. John's wort because they can increase the breakdown of telaprevir and decrease the effectiveness. Telaprevir should be used with caution with warfarin (Coumadin) because telaprevir can increase or decrease warfarin (Coumadin) breakdown, increasing or decreasing the effect of warfarin. Telaprevir can slow the breakdown of these medications and increase their levels in the body, leading to increased side effects and toxicity.

Nikita Gorshkov Dec 25, 2011, 12:00:27 AM

A mark against this young prince is its orphan status. Next in line for the title is the co-formulation of rilpivirine (TMC278) and Truvada (which is itself a combination of tenofovir + emtricitabine). Although no new data were presented on rilpivirine at this conference, the phase 3 results are expected to be available in several months.

icebreak Jan 21, 2012, 6:30:17 AM

Atripla may lead to bone problems, including bone pain or bones getting soft or thin, which may lead to fractures. A generic version became available in the U.S. in October 2020. The efavirenz in Atripla can significantly decrease the effectiveness of Vfend; Vfend can significantly increase the risk of efavirenz side effects. Consult the Atripla package insert for more details: Before taking this medication, tell your doctor if you have kidney disease, liver disease (including hepatitis B), or a history of depression/suicidal thoughts. These include: Combivir, Epivir, Epzicom, Rescriptor, Triumeq, Trizivir, and Viramune.

Booker B May 27, 2014, 4:43:16 PM

As with other antiviral agents in this class, the greatest safety concern is that it may reactivate hepatitis B virus (HBV) in coinfected patients. Although no participants in premarketing studies experienced reactivation, patients should be monitored for HBV reactivation during and after treatment. Glecaprevir/pibrentasvir is not recommended for patients with moderate to severe hepatic impairment (Child-Pugh class B and C). Glecaprevir/pibrentasvir has the potential to interact with several drugs, such as rifampin, atazanavir (Reyataz), carbamazepine (Tegretol), efavirenz (Sustiva), and St. John's wort.

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