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sumatriptan injection instructions

Possibility of serious cardiac side effects Triptan, a serotonin-receptor 1B and 1D agonist used as an immediate treatment for cluster headaches and migraines with or without aura

Other names for this medication:
Onzetra, Imitrex, Zembrace, Tosymra, Treximet, Sumavel

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Description

Make sure to go over the risks and advantages of using sumatriptan with your doctor. This medication is a member of the triptan class of drugs. In addition to not being used to treat cluster headaches, it is not used to prevent migraines. Other than migraine headache pain, it won't reduce any other kind of pain. Many people discover that sumatriptan completely relieves their headaches. Others discover that, despite the fact that their headaches are still present, they are significantly less painful and can resume their regular activities. Some people, particularly those who have heart or blood vessel disease, have experienced serious side effects from sumatriptan. Only a doctor's prescription is required to purchase sumatriptan. Sumatriptan is not your typical painkiller. Sumatriptan is typically prescribed to patients whose headaches are not relieved by acetaminophen, aspirin, or other painkillers. Adults with acute migraine headaches, aura or not, are treated with sumatriptan nasal spray and powder. Sumatriptan often relieves other symptoms that occur together with a migraine headache, such as nausea, vomiting, sensitivity to light, and sensitivity to sound. Sumatriptan works in the brain to relieve the pain from migraine headaches.

Dosage

Check with your doctor as soon as possible after taking the other medication. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If it has been at least two hours since the last spray, you may take another dose (22 mg). If it has been at least two hours since the previous spray, you may use another dose (5 mg, 10 mg, or 20 mg). If at least an hour has passed since the previous spray, you can use another one. Ask your doctor ahead of time about any other medicine you might take if sumatriptan does not work. In case you have any questions, consult your doctor. To get the medication into your nose, give the mouthpiece a strong blow. Children—Your doctor will decide the appropriate use and dosage. Not advised for use with children. Avoid getting any of it on your skin or in your eyes. Don't look down because doing so could cause the medication to drip out of your nose. Do not blow while pressing the white button. Don't take it in larger amounts, more frequently, or for a longer period of time than recommended by your doctor. Never take more than three doses in a 24-hour period. Do not use more than 30 mg in a 24-hour period (one day). Use no more than 40 mg in a day that is 24 hours long. Use no more than 44 mg (4 nosepieces) in a day that is 24 hours long. For headaches other than your typical migraines, avoid taking sumatriptan. Even if you experience an aura, which are signs of an impending migraine, you should hold off using sumatriptan until the headache pain begins. While taking slow, deep breaths through your nose, firmly press the plunger all the way up. Follow your doctor's orders or the directions on the label. Adults should take 22 milligrams (mg) of nasal dosage form (nasal powder) per day, one nosepiece in each nostril for a total of two nosepieces. Adults should administer Imitrex® in the nasal dosage form (nasal solution) in doses of 5 milligrams (mg), 10 mg (2 sprays in one nostril or 1 spray in each nostril), or 20 mg (1 spray into one nostril) to treat migraine headaches. Fully press and release the white piercing button on the device body to pierce the capsule inside the nosepiece. Prior to using sumatriptan, gently blow your nose to clear your nostrils. Close one nostril by gently pressing it shut. Headaches that are not relieved by sumatriptan are sometimes caused by conditions that need other treatments. Between your thumb and first two fingers, hold the device straight up. Immediately rinse it off if it does happen to touch these areas. You may use one more dose of sumatriptan at least one hour (for TosymraTM) or two hours (for Imitrex® or OnzetraTM) after the first dose if you feel significantly better after taking sumatriptan but your headache returns or worsens after a while. Changes to your dose should only be made if your doctor instructs you to. The spray nozzle's tip should be angled outward as you insert half of it into the open nostril. Make a tight seal with the nosepiece by inserting it into the nostril. Consult your physician instead. Breathe slowly through your nose and out through your mouth while keeping your head upright. Simply press it once. To remove the first nosepiece, press the transparent tab. Carefully read and adhere to the instructions. Your nostril should be free of the device. Remove the reusable delivery device's clear device cap, then take out the disposable nosepiece from its foil pouch. Finally, click the disposable nosepiece into the delivery system's body. To finish the prescribed dosage, repeat the same procedures but insert a second nosepiece into the opposite nostril. For ten to twenty seconds, do this again. A patient information sheet and patient instructions are included with the purchase of sumatriptan. Only the nose should be used to administer sumatriptan. The XsailTM breath-powered delivery system administers sumatriptan. The amount of medicine that you take depends on the strength of the medicine. The device is then rotated and the mouthpiece inserted between the lips. The dose of sumatriptan will be different for different patients. The following information includes only the average doses of sumatriptan. Throw the used nosepiece in the trash can. Tilt your head back slightly. Use sumatriptan as soon as the headache starts to relieve your migraine as quickly as possible. To use the nasal powder: Utilizing the nasal spray: Tosymra™: Adults—10 mg given as 1 spray in one nostril. Sumatriptan should only be used as prescribed by your doctor. After taking the nosepiece out of the foil pouch, use it right away. Sumatriptan side effects may become more likely if used excessively. You might detect liquid in your throat or nose.

Overdose

If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help.

Storage

How should any unneeded medications be disposed of? Ask your healthcare provider. Information on the precise dosage of Sumatriptan Avoid storing unused or outdated medications. Do not keep in the freezer or refrigerator. Avoid getting frozen. Keep away from children's reach. Away from heat, moisture, and bright light, keep the medication at room temperature in a closed container.

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Side effects

If you experience any of the following symptoms: feeling hot or cold; a flushed or itchy face; irritation or burning in your nose or throat; nosebleeds; or dizziness or slight trembling, do not operate a motor vehicle, operate machinery, or operate tools. If these symptoms bother you or do not go away, consult a doctor. Sumatriptan should not be taken in further amounts if the following symptoms persist or worsen: tightness or tingling in your face, arms, legs, or chest unusual feelings of heaviness in your face, arms, legs, or chest feelings of warmth or cold in your face, arms, legs, or chest These symptoms typically pass quickly. However, many individuals experience few or no side effects at all. Seek immediate medical attention if they persist, intensify, or become severe. Stick to simple meals when you are able to eat and avoid fatty or spicy foods. Try taking small, frequent sips of water if you're feeling under the weather to prevent dehydration. Sumatriptan may, in extremely rare circumstances, cause a severe allergic reaction (anaphylaxis). Sumatriptan may cause side effects, just like any medication. A doctor should be consulted if the bleeding (where you gave yourself the injection) worsens, becomes painful or inflamed, or persists for more than a few days. In particular, if you are taking a blood-thinning medication like warfarin or rivaroxaban, have haemophilia, or any other condition that prevents your blood from clotting properly, seek immediate medical attention if the bleeding does not stop after 10 to 15 minutes. Seek immediate medical help if the bleeding does not stop after 10 to 15 minutes, especially if you're taking a blood-thinning medicine such as warfarin or rivaroxaban, or you have haemophilia or any other condition that means your blood cannot clot properly. bad taste in your mouth – try chewing sugar-free gum. bruising or swelling (where you gave yourself the injection) – this is usually mild and will go away after 1 to 3 days. Dehydration symptoms include feeling tired, dizzy, or unsteady on your feet. If you start to feel dizzy, lie down to prevent fainting and then sit until you feel better. Some of the side effects are similar to the symptoms of migraine or cluster headaches. Talk to your doctor or pharmacist if any of these side effects bother you or last longer than a few days: feeling or being sick (nausea or vomiting); feeling dizzy, unsteady on your feet; or tired; feeling hot or cold; or face flushing red; with the nasal spray, irritation or burning in your nose or throat; nosebleeds; or a bad taste in your mouth; with the injections; bruising or swelling where you gave yourself the injection; bleeding where you gave yourself the injection. More than one in 100 people experience these common side effects. Most often, they are mild and transient. What to do if you feel sick or want to throw up (nausea or vomiting); this could be a symptom of a migraine.

Interactions

Alfentanil Amineptine Amitriptyline Amitriptylinoxide Amoxapine Amphetamine Benzhydrocodone Benzphetamine Buprenorphine Bupropion Butorphanol Citalopram Clomipramine Codeine Desipramine Desvenlafaxine Dexfenfluramine Dextroamphetamine Dibenzepin Dihydrocodeine Dolasetron Doxepin Duloxetine Escitalopram Fenfluramine Fentanyl Fluoxetine Fluvoxamine Granisetron Hydrocodone Hydromorphone Imipramine Lasmiditan Levomilnacipran Levorphanol Lisdexamfetamine Lithium Lofepramine Lorcaserin Melitracen Meperidine Metaxalone Methamphetamine Milnacipran Mirtazapine Morphine Morphine Sulfate Liposome Nalbuphine Nefazodone Nortriptyline Ondansetron Opipramol Oxycodone Oxymorphone Palonosetron Paroxetine Pentazocine Protriptyline Reboxetine Remifentanil Sertraline Sibutramine St John's Wort Sufentanil Tapentadol Tianeptine Tramadol Trazodone Trimipramine Venlafaxine Vilazodone Vortioxetine Ziprasidone Almotriptan, Bromocriptine, Dihydroergotamine, Eletriptan, Ergoloid Mesylates, Ergotamine, Frovatriptan, Furazolidone, Iproniazid, Isocarboxazid, Moclobemide, Methylergonovine, Methysergide, Phenelzine, Procarbazine, Rasagiline, Rizatriptan, Safinamide, While some medications should never be combined, in other circumstances two distinct medications may be used together even if an interaction may happen. Given the potential for interactions, some medications shouldn't be taken at or close to mealtimes or when consuming specific foods. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. If your doctor prescribes both medications at once, he or she may alter the dosage or frequency at which you take either or both. Your doctor may decide to adjust the dosage in these circumstances or prescribe additional safeguards. The interactions listed below have been chosen because of their potential significance; they are not, however, all-inclusive. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Using sumatriptan with any of the following medicines is not recommended. Sumatriptan shouldn't typically be taken with any of the following medications, but it may be necessary in some circumstances. Your doctor should be informed right away if you take any of the medications on the following list while taking sumatriptan. In addition to changing some of the other medications you take, your doctor may decide not to treat you with this particular medication.

Contraindications

Inform your physician and pharmacist, prior to taking sumatriptan, if you have any allergies to it, any other medications, or any of the components found in sumatriptan tablets.

How does it compare with other medicines for cluster headaches?

Ordinary painkillers do not help with cluster headaches because they take too long to work. The headache is often gone before the painkiller starts to take effect. Cluster headaches are usually treated with oxygen therapy, either on its own or together with a triptan (such as sumatriptan or zolmatriptan). Sumatriptan comes as injections or a nasal spray for cluster headaches and zolmatriptan comes as a nasal spray. The tablets and capsules will not work for cluster headaches. Opioids (such as codeine and morphine) or ergots (such as ergotamine) are not recommended for treating cluster headaches.

Ubrelvy vs Imitrex (sumatriptan): How do they compare?

Ubrelvy and Imitrex are both oral tablets used to treat migraine, but there are differences in the way they work. Ubrelvy prevents a protein called CGRP thought to play a role in migraine attacks from binding to its receptor and Imitrex is thought to bind to serotonin 5‑HT1B/1D receptors, and inhibit pro-inflammatory substances Although no head-to-head comparison trials compare Ubrelvy to Imitrex, indirect evidence suggests that overall, Ubrelvy is no more effective, and may be inferior to Imitrex at relieving migraine in adults who are able to tolerate triptans. For those adults with moderate-to-severe migraine attacks that cannot tolerate triptans or who have found them ineffective, Ubrelvy is beneficial for treating migraines compared to no treatment. Ubrelvy is associated with fewer side effects than Imitrex, but is more expensive, costing almost twice as much.

When should sumatriptan be avoided?

You should not use this medicine if you have used an MAO inhibitor (MAOI) such as phenelzine (Nardil®) or tranylcypromine (Parnate®) within the past 2 weeks. Do not use this medicine if you have taken other triptan migraine medicines or ergot-type medicines within the past 24 hours.

Ubrelvy vs Imitrex (sumatriptan): How do they compare?

Ubrelvy and Imitrex are both oral tablets used to treat migraine, but there are differences in the way they work. Ubrelvy prevents a protein called CGRP thought to play a role in migraine attacks from binding to its receptor and Imitrex is thought to bind to serotonin 5‑HT1B/1D receptors, and inhibit pro-inflammatory substances Although no head-to-head comparison trials compare Ubrelvy to Imitrex, indirect evidence suggests that overall, Ubrelvy is no more effective, and may be inferior to Imitrex at relieving migraine in adults who are able to tolerate triptans. For those adults with moderate-to-severe migraine attacks that cannot tolerate triptans or who have found them ineffective, Ubrelvy is beneficial for treating migraines compared to no treatment. Ubrelvy is associated with fewer side effects than Imitrex, but is more expensive, costing almost twice as much.

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Testimonials
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Gabriel Martini Feb 22, 2013, 4:44:52 AM

Dosage Side Effects Speak with your doctor for a full list of side effects that apply to you if you are taking Imitrex. Uses Imitrex is a serotonin receptor blocker that is used to treat migraines with and without aura. If brain hemorrhage or strokes occur, Imitrex should be stopped If you overuse Imitrex, it can cause an overuse headache, which may require Imitrex detoxification. Serotonin syndrome can occur with Imitrex, especially if other serotonin medications are used at the same time, if this occurs stop Imitrex.

James Heck Jun 9, 2019, 6:04:27 AM

* Dosage: • In controlled clinical trials, single doses of 25, 50, or 100 mg of sumatriptan tablets were effective for the acute treatment of migraine in adults. The choice of dose should therefore be made on an individual basis, weighing the possible benefit of a higher dose with the potential for a greater risk of adverse events. Apply Camphotrex to affected areas not more than 3 to 4 times daily as directed.

user6669 Dec 26, 2011, 12:45:17 PM

Sumatriptan belongs to a group of medicines called triptans, or serotonin agonists. However, there may be other safer alternatives - it’s best to talk to your doctor to discuss Sumatriptan and other migraine medicine. If your first dose of Sumatriptan does not relieve your migraine, you can also use painkillers. If your migraines are severe, your doctor may decide that it is worth the risk.

E smith Dec 20, 2014, 2:03:01 AM

Paediatric population The efficacy and safety of sumatriptan tablets in children aged less than 10 years have not been established. The recommended dose of oral sumatriptan is a single 50mg tablet. No more than 300mg should be taken in any 24 hour period.

Roses May 15, 2014, 11:57:04 AM

The reason behind this is very crucial in treatment. As we all know, medicines sometimes vary in result due to conditions or other factors of the patient. Sometimes people with half knowledge of things mess up with drugs and face situations. Make sure you get proper advice and consultation for this because the medicine, in some circumstances, can narrow down blood vessels more than enough and can increase the side effects of both drugs.

John aka hot2use Feb 15, 2016, 5:48:59 PM

The pharmacokinetics do not differ significantly from a younger population but, until further clinical data are available, the use of Sumatriptan in patients aged over 65 years is not recommended. It is equally effective at whatever stage of the attack it is administered. Imigran is recommended as monotherapy for the acute treatment of migraine and should not be given concomitantly with ergotamine or derivatives of ergotamine (including methysergide) (see section 4.3). The recommended adult dose is a single 6mg subcutaneous injection for each cluster attack. Adult: The recommended adult dose of Imigran is a single 6 mg subcutaneous injection.

efkan Jul 27, 2019, 3:59:46 AM

Niche Generics Ltd would like to inform you that Sumatriptan Niche 50mg and 100mg is being discontinued. {openx:269} Should you have any queries please do not hesitate to contact Niche Generics at (01) 8392355

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