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avanafil tablet

Patient information on avanafil that has been reviewed by a doctor, including a description, dosage information, and instructions.

Other names for this medication:
Spedra, Stendra

Similar Products:
Uroxatral, Finasteride, Tadapox, Casodex, Veltride, Viagra, Sildalis, Dutas, Vpxl, Alfuzosin, Duprost, Dutagen


The phosphodiesterase type 5 (PDE5) that specifically degrades cGMP in the corpus cavernosum, a region around the penis, is inhibited by avanafil. Avanafil is a selective phosphodiesterase 5 (PDE5) enzyme inhibitor used for the treatment of erectile dysfunction caused by diabetes, age induced oxidative stress or other complications. Blood flow to the corpus cavernosum is boosted by cyclic GMP, which also relaxes smooth muscles. Increased penile blood flow brought on by the relaxation of the corpus cavernosal smooth muscle and the penile arteries is what leads to penile erection during sexual stimulation. Avanafil's inhibition of phosphodiesterase type 5 (PDE5) improves erectile function by raising levels of cGMP. Nitric oxide (NO), which is released by nerve terminals and endothelial cells, mediates this reaction by inducing the synthesis of cGMP in smooth muscle cells.


Follow the directions on your prescription label carefully. The initial dose for the majority of patients is 100 mg, which should be taken as needed, about 30 minutes prior to sexual activity. Follow your doctor's instructions for taking this medication exactly. The dosage of Stendra (avanafil) ranges from 50 mg to 200 mg. Your doctor may recommend a dose based on the following: other medical conditions you have; other medications you take; and how you react to this medication. You and your healthcare provider should decide on the lowest dose of avanafil that works for you. You should take the lowest dose of avanafil that works for you. If necessary and based on efficacy and tolerability, your healthcare provider may adjust your dose.

Missed dose

You are unlikely to be on a dosing schedule since avanafil is taken as needed.


Call your doctor or the nearest poison control center if you take too much avanafil, or go to the hospital right away for emergency care.


Maintain refrigeration between 20 and 25 °C.

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Side effects

The most frequent adverse effects (greater than or equal to 2%) are headache, flushing, nasal congestion, nasopharyngitis, and back pain.


Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. For more information, consult your physician or pharmacist. Tell your doctor right away if you take: nitrate medications like isosorbide dinitrate (Isordil), isosorbide mononitrate (Imdur, ISMO), and nitroglycerin (Nitro-BID, Nitro-Dur, Nitroquick, and Nitrostat); HIV protease inhibitors like ritonavir (Norvir), indinavir (Crixivan), saquinavir ( Amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), and verapamil (Calan, Covera, Isoptin, Verelan), nefazodone aprepitant (Emend), other medications or treatments for erectile dysfunction, this is not a complete list of avanafil drug interactions. Inform your physician of all the drugs you take, including vitamins, herbal supplements, prescription and non-prescription medications. These include Hytrin (terazosin), Flomax (tamsulosin), Cardura (doxazosin), Minipress (prazosin), Uroxatral (alfuzosin), Jalyn (dutasteride and tamsulosin), or Rapaflo (silodosin).


A heart attack, stroke, irregular heartbeat, blocked artery, angina (chest pain), high or low blood pressure, heart failure, blood cell issues like sickle cell anemia (a disease of the red blood cells), multiple myeloma (cancer of the plasma cells), leukemia (cancer of the white blood cells), or ulc; as well as any of the following: You should be aware that avanafil is only for use in men. Tell your doctor if you have or have ever had retinitis pigmentosa (a rare inherited eye disease), severe vision loss, or both. Especially if you were told that the vision loss was caused by a blockage of blood flow to the nerves that help you see. Do not use street drugs containing nitrates such as amyl nitrate and butyl nitrate ('poppers') while taking avanafil. Do not take avanafil if you are currently taking or recently took riociguat (Adempas) or nitrates like isosorbide mononitrate (Monoket), isosorbide dinitrate (Dilatrate-SR, Isordil, in BiDil), or nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, among others). Consult your pharmacist for a list of the Aprepitant (Emend), clarithromycin (Biaxin, in Prevpac), diltiazem (Cardizem, Cartia, Tiazac), erythromycin (E.E.S, E-Mycin, Erythrocin), HIV protease inhibitors, and terazosin should all be mentioned. Alpha blockers like alfuzosin (Uroxatral), doxazosin (Cardura), Before taking avanafil, tell your doctor and pharmacist if you are allergic to avanafil, any other medications, or any of the ingredients in avanafil tablets. Calling your doctor to discuss the appropriate use of alcoholic beverages while taking avanafil is advised for pregnant women who take the medication. You should be aware that sexual activity may put a strain on your heart, especially if you have heart disease, so you should inform your doctor or dentist if you are having surgery, including dental surgery. The doctors who treat you will need to know when you last took avanafil if you ever require emergency medical care for a heart condition. Inform all of your healthcare providers that you are taking avanafil if you experience chest pain, wooziness, or nausea during sexual activity. Tell your doctor if you have ever received medical advice to refrain from sexual activity due to health issues, if you've recently had heart surgery, and if you've ever experienced an erection that lasted longer than 4 hours. Nitrates are available as tablets, sublingual tablets (to be taken under the tongue), sprays, patches, pastes, and ointments. Avanafil is not recommended for women, especially if they are, or may become, pregnant or breastfeeding. Your doctor might need to adjust your medication doses or keep a close eye out for any negative side effects.

Can I buy Stendra over counter?

Sildenafil is a cheaper generic medication, giving you an affordable treatment option, but you can only buy branded Avanafil medications which usually cost more. You can buy Sildenafil over the counter as Viagra Connect but Avanafil is prescription only.

Do you need a prescription for avanafil?

It's recommended to take Stendra (avanafil) about 15-30 minutes before sexual activity to give the medication time to kick in. For some people it can work faster, within 15 minutes, and others might take longer. Do I need a prescription for Stendra (avanafil)? Yes, Stendra (avanafil) is a prescription-only medication.

How much is Stendra per pill?

How Much Does Stendra Cost Per Pill? Stendra starts from $59 per use through our online platform for treating ED. We provide Stendra with discreet and convenient home delivery, subject to approval following an online consultation with a licensed healthcare provider.

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raja zohaib May 17, 2010, 8:17:51 PM

Other drugs in this family include Cialis (tadalafil), Levitra (vardenafil), and Stendra (avanafil). The 50 mg dose is the most commonly used dose, although some people may benefit from higher or lower doses. It comes in three doses, 25 mg, 50 mg, and 100 mg. Viagra has been found safe and effective since it was introduced by Pfizer and FDA-approved in the ’90s, but it’s still prescription drugs. Viagra, nicknamed “the little blue pill”, is a drug that is used to treat erectile dysfunction (ED).

vsarunov Jul 22, 2014, 9:35:49 PM

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samorodovv Feb 19, 2020, 2:52:38 PM

Avanafil and Dapoxetine a basic version of well-known drug called Avanafil.... Read More Tadarise is the first drug that was developed to brawl erectile dysfunction. Begin a happy life, full of pleasure with Avana.

John Salem Aug 14, 2016, 7:38:37 PM

Generics are medications created to be the same as brand-name drugs. For example, in clinical trials, 21 percent of people who used Viagra at the normal starting dose of 50mg experienced headaches, while 19 percent experienced flushing. Stendra also works faster than medications like sildenafil and tadalafil.

Ananya Zabin Sep 5, 2014, 6:16:31 AM

Cialis (tadalafil) Cialis and tadalafil (generic Cialis) stand out a little more than the other medications on offer. Spedra (avanafil) Spedra (chemical name avanafil) can prompt an erection in as little as 15 minutes. Impotency caused by psychological problems (such as stress or depression) may need to be treated in a different way to impotency that is caused by physical problems. In the UK, there are various drugs available to treat ED, there are big brand names that you will probably recognise and some of these also have a generic (unbranded) equivalent. So, we are well aware of the problem but what can be done about erectile dysfunction?

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