Side effects
In the event that you experience: For medical guidance on side effects, contact your doctor. Typical negative effects could be: If you experience chest pain, call for emergency assistance. If you experience any of the following symptoms of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat, seek emergency medical attention. Rarely, this may result in life-threatening heart issues. Children's growth may be harmed by ribavirin. Anemia may be induced by ribavirin. consequences of ribavirin (more information) Tell your doctor if your child is not growing at a normal rate while using this medicine. This is not a complete list of side effects and others may occur. You can contact the FDA to report side effects at 1-800-FDA-1088. nausea, vomiting, loss of appetite; fever, chills or shaking; low blood cell counts, anemia; feeling weak or tired; headache, muscle pain; or mood changes, feeling anxious or irritable. vision issues; excruciating upper abdominal pain that radiates to your back; nausea, vomiting, and diarrhea; a new or worsening cough; fever; sharp chest pain; wheezing; and shortness of breath. Severe depression, suicidal or self-destructive thoughts; pale or yellowed skin; dark urine; confusion; or other symptoms of low blood cell counts, such as fever, chills, flu-like symptoms, swollen gums, mouth sores; and
Interactions
Steer clear of alcohol. Ribavirin is used to treat chronic hepatitis C infection; consuming alcohol may make this infection worse. When taking, eat. When taken with a high-fat meal, ribavirin's absorption is slowed and its AUC and Cmax are elevated.
Contraindications
Additionally, a pregnancy test should be performed each month while taking this medication and for six months after stopping it. Alcohol or marijuana (cannabis) can make you more dizzy. Steer clear of alcoholic beverages. Breastfeeding is not advised while taking this medication due to the potential risk to the infant. Inform your doctor or pharmacist if you are allergic to ribavirin or if you have any other allergies before taking it. In particular, mention any blood disorders (such as sickle cell anemia, low hemoglobin, or thalassemia), kidney disease, other liver problems (such as autoimmune hepatitis), heart disease, high blood pressure, breathing issues, pancreas problems (such as pancreatitis), or diabetes to your doctor or pharmacist before using this medication. Until you can do something safely, avoid operating machinery, driving, or doing anything else that requires alertness or sharp vision. When taking this medication, elderly patients may be more susceptible to anemia. Inform your doctor right away if you become pregnant or suspect you might be pregnant. Whether this medication enters breast milk is unknown. It is recommended that female patients or female partners of male patients take a pregnancy test before starting this medication. With age, kidney function decreases. Ribavirin must not be used during pregnancy. Observe the Warning section as well. If you use marijuana (cannabis), consult your physician. Talk to your pharmacist for more details. This medication may cause you to feel lightheaded or cause vision blur. This medication is removed by the kidneys. Inactive ingredients in this product have the potential to cause allergic reactions or other issues.
Ribavirin ( Copegus , Rebetol , Ribasphere , Ribatab , RibaPak , Virazole , CHNO, MW 244.20) occurs as a white, crystalline powder that is freely soluble in water (142 mg/mL at 25°C) and slightly soluble in dehydrated alcohol. Sterile Water for Inhalation, USP, is prepared from Water for Injection, USP, that is sterilized and suitably packaged. Use: This preparation has been used to treat respiratory syncytial virus infection in hospitalized infants and young children. Dissolve the ribavirin and sodium chloride in sufficient Sterile Water for Injection or Sterile Water for Inhalation to final volume and mix well.
If the starting dose is not well tolerated, the dose should be reduced as clinically indicated based on haemoglobin levels * If a more normalized dose of ribavirin (by weight and renal function) cannot be reached for reasons of tolerability, 24 weeks of Harvoni + ribavirin should be considered in order to minimize the risk for relapse. Patients with decompensated cirrhosis irrespective of transplant status Harvoni + ribavirin for 12 weeks (see section 5.1) - Harvoni (without ribavirin) for 24 weeks may be considered in patients who are ineligible for or intolerant to ribavirin. Harvoni treatment should be initiated and monitored by a physician experienced in the management of patients with CHC. No dose adjustment is warranted for elderly patients (see section 5.2). However, it is not recommended that ribavirin be increased to the originally assigned dose (1,000 mg to 1,200 mg daily).
In adults a starting ribavirin dose of 400 mg administered orally in two divided doses with food is recommended. No dose adjustment of Sovaldi is required for patients with mild or moderate renal impairment. If it is after 18 hours then patients should be instructed to wait and take the next dose at the usual time.
Additionally, many of the patients had other difficult-to-treat indices, including cirrhosis (6–9%), high viral load (90%), and African-American ancestry (14–17%). The second group received boceprevir plus peginterferon-ribavirin for 32 weeks, and those with a detectable HCV RNA level at week 8 received peginterferon-ribavirin and placebo for another 12 weeks. It occurred in half of the patients who received boceprevir and by about a third of the patients taking peginterferon alfa-2b plus ribavirin at the standard dose. All patients received a month of peginterferon alfa-2b and ribavirin before being randomized to one of three arms.
This may worsen your condition and can lead to a possibly fatal heart attack. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used to treat severe acute respiratory syndrome (SARS). Doing so will decrease the risk of serious side effects. Women and men who are taking ribavirin must avoid pregnancy by using two forms of reliable birth control (such as latex condoms and birth control pills) during treatment with this drug and for 6 months after this medication has been stopped.
Some side effects associated with this treatment include fatigue, headache, nausea, insomnia, and anemia (low red blood cells). There are 6 HCV genotypes (genotype 1-6); genotype 1 is the most prevalent in the United States. In clinical trials, Incivek + ribavirin + peglyated interferon produced SVR in 61.9% to 77.9% of patients.