Side effects
Call your doctor for medical advice about side effects. Reglan injections can cause infusion-related side effects if they are administered too quickly. Common side effects of Reglan include headache confusion difficulty sleeping and feeling agitated, sleepy, tired, dizzy, or exhausted. Reglan can cause serious side effects. Look at "Drug Precautions." Tell your doctor about any side effects that bother you or do not go away. Tell your doctor or nurse right away if this happens. These are not all of the potential Reglan side effects. When getting a Reglan injection, you might experience a brief period of extreme anxiety and restlessness followed by drowsiness. The longer and/or more Reglan you take, the possibility of side effects increasing increases. When you stop taking Reglan (go through withdrawal), you might experience headaches, lightheadedness, or anxiety. Call 1-800-FDA-1088 to contact the FDA and report side effects. After stopping Reglan, side effects might still persist.
Interactions
Inquire with your pharmacist about the safe use of those products. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Without your doctor's permission, you should never start, stop, or modify the dosage of any medications. Drug interactions may alter how your medications function or raise your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Food and medications pass through the stomach more quickly when you take metoclopramide, which may affect how well some medications are absorbed. Some products that may interact with this drug include: antipsychotic drugs (such as aripiprazole, haloperidol), atovaquone, dopamine agonists (such as cabergoline, pergolide, ropinirole), fosfomycin, MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine), pramlintide, phenothiazines (such as promethazine, prochlorperazine), rivastigmine. To find out if any of the medications you are taking may be impacted, check with your doctor or pharmacist. If you are taking any additional medications that make you sleepy, such as alcohol, marijuana (cannabis), antihistamines (such as cetirizine and diphenhydramine), sleep or anxiety medications (such as alprazolam, diazepam, and zolpidem), muscle relaxants, or opioid painkillers (such as codeine), let your doctor or pharmacist know. This document does not contain all possible drug interactions.
Contraindications
Alcohol may make some side effects of Reglan injection worse, such as feeling sleepy. If any of the following apply to you: you feel depressed or have suicidal thoughts; you have a high fever, stiff muscles, trouble thinking, a very rapid or uneven heartbeat, increased sweating; you have muscle movements you cannot control or stop; you have muscle movements that are new or unusual; you have any of these symptoms, call your doctor right away; and you are receiving a Reglan injection. If you experience uncontrollable movements, such as lip-smacking, chewing, puckering up your mouth, frowning or scowling, sticking out your tongue, blinking and moving your eyes, shaking of your arms and legs (dystonia), call your doctor right away. Suicidal ideation, depression, and actual suicide As soon as you are given a Reglan injection, avoid operating machinery, operating heavy machinery, and performing other risky tasks. If you have seizures, pheochromocytoma, an adrenal gland tumor, or any of the following conditions, you should not take Reglan. If you already have Parkinson's disease, Reglan may make your symptoms worse. NMS can cause death and must be treated in a hospital. Reglan use can result in NMS, a very uncommon but serious condition. NMS, or Neuroleptic Malignant Syndrome. Parkinsonism. Reglan can cause serious side effects, including: Serious side effects have been reported including: Abnormal muscle movements called tardive dyskinesia (TD). Reglan injection may cause sleepiness. Taking Reglan can lead to depression in some people. Some Reglan users have killed themselves (committed suicide). Symptoms include slight shaking, body stiffness, trouble moving or keeping your balance. High fever, tense muscles, confusion, an irregular or extremely fast heartbeat, and increased sweating are all signs of NMS. There is no cure for TD, but after you stop taking Reglan, your symptoms might get better or disappear altogether. These movements primarily involve the muscles of the face. These muscle spasms may result in erroneous postures and movements of the body. Children and adults under the age of 30 experience these spasms more frequently. These spasms usually start within the first 2 days of treatment. Even if Reglan is discontinued, they might persist. These movements are not under your control. You might consider harming or killing yourself. If you are older, particularly if you are a woman, if you have diabetes, or if you have any of the conditions listed above, you should not take Reglan for longer than 12 weeks. Your doctor cannot predict whether you will develop TD if you take Reglan. The more Reglan you take for a longer period of time, the greater your risk of developing TD.
Children may also suffer pancreatitis and toxic megacolon, which have been reported. Drugs can decrease the propulsion of intestinal contents and may overstress the effects of diphenoxylate, which can cause constipation. If the drug is taken at a larger dosage, it can have unpleasant side effects due to the greater quantity of atropine. In order to prevent abuse of diphenoxylate, atropine is combined with diphenoxylate in small quantities.
The drug combination can also be made from over-the-counter versions of pyridoxine (vitamin B6) and doxylamine (Unisom). Many patients may require two to four tablets per day. Pyridoxine/doxylamine was first marketed in the U.S. in 1956 as Bendectin. Despite this, no new medications for nausea in pregnancy were approved for 30 years.
This combination medicine was approved by the US FDA in 1988. Note – one of the benefits of Rytary is that patients may be able to modestly reduce the number of pills they take as they switch from Sinemet to Rytary. Side Effects and Precautions muscle contractions; nausea; jerky or twisting muscle movements. Dosage It comes with an orally-disintegrating tablet, a tablet, and an extended-release tablet.
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