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prograf 1mg price

Learn about interactions, side effects, and indications. Prograf is used to stop your body from rejecting a kidney, liver, or heart transplant.

Other names for this medication:
Advagraf, Tacrolimus, Envarsus, Protopic, Astagraf, Modigraf

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Avoid being around UV light, including that from sun and tanning beds. While taking Prograf, avoid consuming grapefruit or grapefruit juice. Prograf should not be stopped or changed without first consulting your doctor. Prograf, for instance, must always be taken with food if you decide to do so. If you take your first dose at 7:00 in the morning, for instance, you should take your second dose at 7:00 in the evening. Take Prograf every day at the same time, separated by 12 hours. Following your doctor's instructions precisely, take Prograf. Take Prograf with or without food, but make sure to take it consistently each time. Prograf should be taken at the same time every day to ensure that you have enough of the medication in your system to provide your transplanted organ with the constant medication it requires. Put on protective clothing and apply sunscreen. If necessary, your doctor might adjust how much Prograf you take. How many Prograf capsules to take and when will be determined by your doctor.


Afterward, doses will be modified in light of an evaluation of organ rejection and how you are responding to the medication. Follow the directions on your prescription label carefully. Take this medication exactly as prescribed by your doctor. The dosage your physician prescribes may depend on the kind of transplant you are receiving. The recommended initial dose of Prograf capsules in adults to prevent rejection of a: kidney transplant in combination with azathioprine is 0.2 mg/kg/day kidney transplant in combination with MMF/IL-2 receptor blocker is 0.1 mg/kg/day liver transplant is 0.10- 0.15mg/kg/day heart transplant is 0.075 mg/kg/day The recommended initial dose of Prograf injection is 0.03-0.05 mg/kg/day in kidney and liver transplant and 0.01 mg/kg/day in heart transplant given as a continuous infusion into a vein (IV). Children should take Prograf capsules at a starting dose of 0.15 to 0.20 mg/kg/day to prevent rejection of a liver transplant.

Missed dose

Never combine two doses into one. If it is almost time for your next dose, skip the missed dose and take the medication as soon as you remember.


If you take too much Prograf, call your doctor or head straight to the emergency room of the closest hospital.

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Side effects

Call your physician right away if you have additionally: For medical advice about side effects, contact your doctor. Call your doctor right away if you have signs of infection such as: fever, chills, flu symptoms, cough, sweating, painful skin sores, skin warmth or redness, or muscle aches. The following are frequent side effects of Prograf: Get emergency medical help if you have signs of an allergic reaction to Prograf: hives; difficult breathing; swelling of your face, lips, tongue, or throat. (More Information) Prograf side effects This is not a complete list of side effects and others may occur. You could experience an increased risk of infections, including serious or fatal ones. Call 1-800-FDA-1088 to contact FDA and report side effects. general malaise, pain or swelling near your transplanted organ, headaches, vision changes, pounding in your neck or ears, confusion, behavioral changes, tremors, a seizure, fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); chest pain, cough, trouble breathing (even while lying down); high blood sugar - increased thirst, increased urination, hunger, hunger, fruity breath Low levels of magnesium or phosphate, low levels of potassium, high cholesterol or triglyceride levels, low levels of magnesium or phosphate, low blood cell counts, infections, fever, nausea, diarrhea, constipation, stomach pain, weakness, and pain around the heart. Other symptoms include numbness or tingling in the hands and feet, difficulty falling asleep (insomnia), and swelling in the hands, legs, ankles, or feet.


Inform your physician of all the drugs you take, including vitamins, herbal supplements, prescription and non-prescription medications.


If any of these symptoms occur while taking Prograf, contact your doctor right away. If you experience any infection-related symptoms, such as fever, sweats, chills, a cough or flu-like symptoms, muscle aches, or warm, red, or painful skin patches, you should contact your doctor right away. Diabetes raises your blood sugar levels. If you experience any of the following symptoms, call your doctor right away: frequent urination, increased thirst or hunger, blurred vision, confusion, drowsiness, loss of appetite, nausea, vomiting, or stomach pain, kidney issues. People who take Prograf have an increased risk of getting some kinds of cancer, including skin and lymph gland cancer (lymphoma). increased risk of infection. A serious side effect of prograf is an increased risk of developing cancer. Your immune system's capacity to combat infections may be decreased by prograf. Prograf is a medicine that affects your immune system. Patients receiving Prograf are at risk for developing life-threatening infections. Shortness of breath, chest pain, feeling lightheaded or faint, gastrointestinal perforation (a hole developing through the wall of the esophagus, stomach, small intestine, large intestine, rectum, or gallbladder), and severe allergic reactions to the injection are all indications that you may be experiencing heart problems while taking Prograf. If you experience any of these side effects while taking Prograf, contact your doctor right away: wheezing, itching, or rash. If you are allergic to Prograf or any of its ingredients, including HCO-60 (polyoxyl 60 hydrogenated castor oil), do not take Prograf. Confusion, coma, muscle tremors, numbness and tingling, headache seizures, and high blood potassium levels could be symptoms of a serious nervous system issue. Flu vaccine through the nose, measles, mumps, rubella, polio by mouth, BCG (TB vaccine), yellow fever, chicken pox (varicella), typhoid Avoid exposure to sunlight and UV light, including tanning beds, while taking Prograf. Avoid receiving any live vaccines. During the course of your Prograf treatment, your doctor may order specific tests to check for diabetes. During the course of your Prograf treatment, your doctor may order specific tests to monitor your kidney function. In order to monitor your potassium level while you take Prograf for high blood pressure, your doctor may order specific tests. While you are taking Prograf, your doctor will check your blood pressure.

Is Prograf a brand name?

Tacrolimus comes as the brand-name drugs Astagraf XL, Envarsus XR, Prograf, and Protopic. Like the different forms of generic tacrolimus, these brand-name drugs do not all have the same uses.

What is the difference between Prograf and Advagraf?

Both Prograf and Advagraf contain the immunosuppressant tacrolimus; however, Prograf is an immediate-release formulation to be taken every 12 hours when used for the prevention of organ rejection, whereas Advagraf is an extended-release formulation that is to be taken every 24 hours.

Is Prograf a steroid?

Is tacrolimus (Prograf) a steroid? No, tacrolimus (Prograf) is not a steroid or corticosteroid but it belongs in a drug class called "calcineurin-inhibitors." Sometimes corticosteroids and calcineurin inhibitors are used together to prevent transplant rejections.

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gmclelland Feb 13, 2016, 5:11:54 PM

Tacrolimus blood trough levels should be determined approximately 12 hours post-dosing of Modigraf granules, just prior to the next dose. An initial oral dose of 0.30 mg/kg/day should be administered in 2 divided doses (e.g. Materials containing polyvinyl chloride (PVC) should not be used (see section 6.2). The total daily dose of Modigraf granules should be administered in 2 equal doses.

ChurchSkiz Apr 13, 2014, 1:37:51 AM

This may reduce the effectiveness of ketoconazole or increase digoxin toxicity. Omeprazole potentially can increase the concentrations in blood of diazepam (Valium), warfarin (Coumadin), and phenytoin (Dilantin) by decreasing the elimination of these drugs by the liver. Accordingly, the dose of saquinavir may need to be reduced to avoid toxicity, and the doses of nelfinavir and atazanavir may need to be increased to maintain efficacy. Omeprazole reduces the activity of these enzymes and potentially can reduce the activity of clopidogrel. Omeprazole may increase blood levels of methotrexate (Rheumatrex, Trexall) and tacrolimus (Prograf).

Petr Reshetin Dec 10, 2012, 2:17:34 AM

Prograf XL debe administrarse generalmente con el estomago vacio o al menos 1 hora antes o 2-3 horas despues de las comidas, para obtener Ia maxima absorcion Se recomienda administrar Ia dosis diaria oral de Prograf® XL una vez al dia par Ia manana. Progra® XL es una formulacion oral de tacrolimus que se toma una vez a/ dia. Tratamiento del rechazo de aloinjerto resistente al tratamiento con otros productos medicinales inmunosupresores en pacientes adultos.

jdthood Jul 19, 2019, 12:07:26 AM

Transplant doctors know that sometimes these interventions must be used long term for overall health. The results were good, but her cardiologist wanted a more extensive study before agreeing to discontinue her blood thinner medication. The elevated risk of infection is not the only concern.

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