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Prochlorperazine
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prochlorperazine brand name

It functions by reducing excessive brain excitement. Conventional antipsychotics, which include prochlorperazine, are a group of drugs. Children under the age of 2 or who weigh less than 20 pounds (about 9 kilograms) should not be treated with prochlorperazine for any condition. To treat extreme nausea and vomiting, prochlorperazine is available as tablets and suppositories. As a short-term treatment for anxiety that was resistant to other medications, prochlorperazine tablets are also employed. Tablets containing prochlorperazine are also employed to treat the signs and symptoms of schizophrenia, a mental disorder that results in disturbed or unusual thinking, a lack of interest in daily activities, and strong or inappropriate emotions.

Other names for this medication:
Compro, Compazine

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Skelaxin, Chlorpromazine, Buspar, Anafranil, Clozaril, Clozapine, Thioridazine, Thorazine, Loxapine, Mellaril, Atomoxetine, Metaxalone, Loxitane

Description

Updated: April 22, 2015

Dosage

Even if you feel good, keep taking prochlorperazine. Throw away used items, and wash your hands thoroughly. Never stop taking prochlorperazine without consulting your doctor first. Use only as directed by your doctor, neither more nor less of it, nor more frequently. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. For a brief period of time, keep buttocks joined. The suppository may come out if it isn't inserted past this sphincter. Before removing the wrapper, if the suppository is soft, hold it under cold water or put it in the refrigerator for a few minutes to harden it. Prochlorperazine may help control your symptoms if you're using it to treat schizophrenia, but it won't make your condition go away. If you do not have this lubricant, moisten your rectal area with cool tap water. If you suddenly stop using prochlorperazine, you may experience withdrawal symptoms such as nausea, vomiting, dizziness, and shakiness. If you were instructed to use only half of the suppository, slice it in half lengthwise using a tidy, precise blade. In order to pass the muscular sphincter of the rectum, insert the suppository with the pointed end first, about 1/2 to 1 inch (1.25 to 2.5 centimeters) in infants and 1 inch (2.5 centimeters) in adults. Your upper leg should be bent forward and toward your stomach as you are lying on your side with your lower leg straightened out. Open the upper buttock to reveal the genital region. Instead of using Vaseline or petroleum jelly, lubricate the tip of the suppository with a water-soluble lubricant like K-Y Jelly. Prochlorperazine comes as a tablet to take by mouth and as a suppository to place in the rectum. Suppositories containing prochlorperazine are typically inserted twice daily. Children typically receive prochlorperazine tablets one to three times daily, while adults typically take them three to four times daily. Put on a disposable glove or fingercot, if desired (available at a pharmacy). Remain lying down for about 15 minutes to avoid having the suppository come out. if there is a wrapper, take it off. Ask your doctor or pharmacist for more details if you believe this medication should be used for something else. Wash your hands thoroughly with soap and water before inserting a prochlorperazine suppository. To allow the suppository's medication to be properly absorbed into the body, try to delay having a bowel movement for about an hour. Keep eating normally unless your doctor instructs you otherwise. The same time(s) each day should be used for prochlorperazine. Use prochlorperazine exactly as directed. Your doctor might prescribe you a low dose of prochlorperazine and gradually increase it, not more frequently than once every two to three days.

Missed dose

Do not take a double dose to make up for a missed one. To continue with your regular dosing schedule, skip the missed dose if it is almost time for the next one. If you miss a dose, take it as soon as you remember.

Overdose

Call 911 right away if the victim has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused. Dial 1-800-222-1222 to reach the poison control hotline in the event of an overdose. At https://www.poisonhelp.org/help, you can also find information online. Overdose signs and symptoms may include agitation, jitteriness, trouble falling asleep or staying asleep, blank expression, drooling, uncontrollable shaking of a body part, sleepiness, coma (loss of consciousness for a while), seizures, irregular heartbeat, fever, dry mouth, and constipation.

Storage

You should not, however, dispose of this medication in the toilet. Instead, using a medication take-back program is the best way to get rid of your medication. All medications should be kept out of the sight and reach of children, as many containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for small children to open. Keep this medication tightly closed in the original container and out of the reach of children. If you do not have access to a take-back program, visit the FDA's Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for more details. Suppositories containing prochlorperazine should be kept in their packaging; do not remove a suppository until just before use. Keep the medication at room temperature, away from sources of extreme heat, and dry (not in the bathroom). To find out about take-back programs in your neighborhood, speak with your pharmacist or get in touch with your city's waste/recycling department. http://www.upandaway.org Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Always lock safety caps and place the medication in a safe location - one that is up and away and out of their sight and reach.

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Side effects

There could be negative effects from prochlorperazine.

Interactions

For more information, consult your physician or pharmacist. Especially tell your doctor if you take: CABERGOLINE/PROCHLORPERAZINE CISAPRIDE/PROCHLORPERAZINE DOFETILIDE/PROCHLORPERAZINE ENTACAPONE/PROCHLORPERAZINE LEVODOPA/PROCHLORPERAZINE METOCLOPRAMIDE/PROCHLORPERAZINE PERGOLIDE/PROCHLORPERAZINE PRAMIPEXOLE/PROCHLORPERAZINE PROCHLORPERAZINE/ROPINIROLE HYDROCHLORIDE PROCHLORPERAZINE/TOREMIFENE CITRATE This is not a complete list of Prochlorperazinedrug interactions. Inform your doctor about every medication you take, including vitamins, herbal supplements, prescription drugs, and over-the-counter medications.

Contraindications

You should be aware that prochlorperazine may cause dizziness, especially when you get up from a lying position. Alcohol can exacerbate these side effects. Also tell the child's doctor if the child has any of the following symptoms: vomiting, listlessness, drowsiness, confusion, aggression, seizures, yellowing of the skin or eyes, weakness, or flu-like symptoms. If you plan to work with organophosphorus insecticides (a class of chemical used to kill insects), let your doctor know as well. If you will be giving prochlorperazine to a child, let the child's doctor know if the child has chickenpox, measles, a stomach virus, an infection of the brain or spinal cord, or any other serious illness. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants; antihistamines; atropine (in Motofen, in Lomotil, in Lonox); barbiturates such as pentobarbital (Nembutal), phenobarbital (Luminal), and secobarbital (Seconal); diuretics ('water pills'); epinephrine (Epipen); guanethidine (not available in the US); ipratropium (Atrovent); lithium (Eskalith, Lithobid), medications for anxiety, irritable bowel disease, mental illness, Parkinson's disease, motion sickness, ulcers, or urinary problems; medications for seizures such as phenytoin (Dilantin); narcotic medications for pain; propranolol (Inderal); sedatives; sleeping pills; and tranquilizers. If you will be taking prochlorperazine to treat nausea and vomiting, it is important to let your doctor know about any other symptoms you are experiencing, especially listlessness, drowsiness, confusion, aggression, seizures, headaches, problems with vision, hearing, speech, or balance, stomach pain or cramps, or constipation. If the child has not been drinking normally, has excessive diarrhea, or appears dehydrated. Inform your doctor and pharmacist if you have any allergies prior to using prochlorperazine, including those to other phenothiazines like chlorpromazine, fluphenazine, perphenazine, promethazine (Phenergan), thioridazine, and trifluoperazine. Ask your doctor about the safe use of alcohol while taking prochlorperazine. Do not operate machinery or drive a car until you know how this medication affects you. Call your doctor if you become pregnant while taking prochlorperazine. If you will be taking prochlorperazine tablets, also tell your doctor if you are allergic to tartrazine (a yellow dye found in some foods and medications) or aspirin. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take. Tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, planning to become pregnant, or if you are breast-feeding. Nausea and vomiting that are experienced along with these symptoms may be a sign of a more serious condition that should not be treated with prochlorperazine. Ptrochlorperazine may cause problems in newborns following delivery if it is taken during the last months of pregnancy. if you are having surgery, including dental surgery, tell the doctor or dentist that you are using prochlorperazine. if you will be having a myelogram (x-ray examination of the spine), tell your doctor and the radiographer that you are taking prochlorperazine. If you intend to engage in strenuous activity or be exposed to high temperatures, let your doctor know. You should be aware that prochlorperazine may make it more difficult for your body to cool down when it becomes extremely hot. To prevent this issue, get out of bed slowly and rest your feet on the floor for a few minutes before standing up. Tell your doctor if you have or have ever had glaucoma (condition in which increased pressure in the eye can cause gradual loss of vision), trouble staying balanced, seizures, an abnormal electroencephalogram (EEG; test that measures electrical activity in the brain), brain damage, pheochromocytoma (tumor on a small gland near the kidneys), breast cancer, any congenital disorder, or any other illness that could require your doctor to change the doses of your medications or monitor you carefully Your doctor will probably tell you not to take prochlorperazine for 2 days before the myelogram and for one day after the myelogram. you should know that this medication may make you drowsy and may affect your thinking and movements, especially at the beginning of your treatment.

What are the effects of prochlorperazine?

Drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Does prochlorperazine cause euphoria?

Prochlorperazine has the ability to be abused and while it is not known to deliver the euphoria that is often delivered by more commonly abused drugs, it can still alter mood and perception, increasing its demand among recreational users.

What is the pill prochlorperazine maleate used for?

Prochlorperazine is an anti-sickness medicine. It can help stop you feeling or being sick (nausea or vomiting). You can take prochlorperazine to treat: morning sickness.

What is Stemetil prochlorperazine maleate used for?

Stemetil contains the active ingredient prochlorperazine. Stemetil is used to treat nausea, vomiting and dizziness due to various causes, including migraine (severe headache).

What is prochlorperazine tablet used for?

Prochlorperazine is an anti-sickness medicine. It can help stop you feeling or being sick (nausea or vomiting). You can take prochlorperazine to treat: morning sickness.

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Testimonials
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Mike Rathbun Dec 18, 2014, 9:50:11 AM

It presents itself as an oral tablet and is generally taken up to three times a day when required. Treats nausea and vomiting associated with migraine Controls the nauseous feeling of migraine Whilst the mode of action isn’t fully known, Prochlorperazine helps alleviate the feeling of nausea associated with general sickness or migraine.

chiken Nov 26, 2015, 4:43:05 AM

Prochlorperazine has the ability to be abused and while it is not known to deliver the euphoria that is often delivered by more commonly abused drugs, it can still alter mood and perception, increasing its demand among recreational users. Prochlorperazine is effective for the short-term treatment of generalized non-psychotic anxiety. The Food and Drug Administration (FDA) has not approved prochlorperazine for treating behavior problems in older adults who have been diagnosed with dementia. This medication is often used to control severe nausea and vomiting, as well as treating the symptoms of schizophrenia.

Jim Gramze Dec 6, 2015, 2:30:52 PM

This is why irregular motion such as that on a plane or boat can lead to nausea. These methods will not work as quickly as medication, however, they are often a good place to start. This type of nausea can affect anyone, but those who experience migraines may be much more susceptible. When the brain detects conflicting information being relayed by the vestibular system and the eyes or muscles, it triggers the feeling of nausea.

amulhol Jan 4, 2013, 9:59:28 PM

I can’t believe I’m only now finding out about your podcasts but please continue to make them for as long as you can. If you aren’t a pharmacist you will still get tons of useful information to improve your practice. As a paramedic, this podcast has really helped me understand the “why” we give certain meds.” “Ideal podcast to listen on the way to my shift. “Love this podcast for anyone working in an ER or ICU. Explains concepts in an easy to understand fashion” “I love listening to this podcast because I can listen to 1 or 2 on my way to work and it provides great info!

karridu Dec 28, 2013, 2:41:10 PM

If you can’t get the drug, how should you treat pain in opiate tolerant patients? Zhongguo yao li xue bao = Acta pharmacologica Sinica 1995;16:311-4. With droperidol unavailable, ondansetron, metoclopramide and promethazine are all suitable options for the treatment of nausea and vomiting.

BraisC Jun 8, 2022, 11:06:05 AM

If you have been supplied the 3 mg buccal tablets (Buccastem® M brand) - the tablets are designed to stick to the inside of your mouth and to dissolve there. If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist. If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. If you drink alcohol, ask your doctor for advice about drinking while you are on prochlorperazine.

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