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Podowart also includes benzoin (10% w/v), which is a gum resin from the trunks of trees in the Styrax family, and aloe vera (2% w/v), which is a plant similar to a cactus that grows in hot climates and is generally used to alleviate sunburn. Podowart is a prescription topical medication primarily used to treat skin warts. Podophyllum resin (20% w/v), which is derived from the roots of the American mandrake and has been used to remove warts since at least the 1820s, is the primary active component.

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By restoring the damaged area and assisting in the formation of new skin layers where the wart once was, it promotes healing at the same time. Podowart functions by preventing wart cells from proliferating. By doing so, the wart is kept from spreading further and eventually dies off, leaving the unwanted growth completely gone.


Generally, you should cover any normal skin around the wart to prevent the medicine from spreading and carefully apply one drop of Podowart at a time to the wart with a toothpick or cotton swab until it is completely covered. However, the precise dosage and application method may change. Depending on your doctor's advice, leave the medication in place for 1 to 6 hours. Then, wash the area thoroughly with soap and water or wipe it with rubbing alcohol to remove it. It is unsafe to get Podowart on normal skin, so wash your hands afterward. For up to six weeks, repeat once daily as necessary. Always pay attention to your doctor's advice and heed any medication-related instructions, as these will be more tailored to your particular situation.

Missed dose

If you miss a dose for any reason, unless it is almost time for your next dose, take it as soon as you can. In that case, skip the missed dose and carry on with your regular schedule.


Use Podowart only as instructed; take care. Never take two doses at once, regardless of whether you missed the previous one. Doing so increases the chance of experiencing side effects.


Podowart must be kept in a location that is between 15 and 30 °C (59 and 86 °F), ideally in a sealed, light-resistant container.

Side effects

However, if they occur frequently or to an unusually high degree, speak with your doctor about using the medication in a lower dose or less frequently. Make sure to inform your doctor if the side effects last for a long time so they can provide you with guidance on continued use. Such symptoms are usually mild and will resolve on their own over time. An unfavorable reaction at the application site is the main side effect of Podowart. A burning sensation, irritated skin, itching, and redness are some examples of this.


Even if they are additional topical medications intended for application to the skin, you should still let your doctor know about any current medications you are taking. Podowart is generally safe to take with other medications and has no known drug interactions.


Make sure to keep the medication out of your mouth, eyes, and other mucous membranes, such as your nose or vagina. Respect your doctor's advice and work with them to find any suitable alternative treatments. If any Podowart gets in your eyes, immediately rinse them out with water and keep doing so for at least 15 minutes to ensure that all of it is removed. If you or anyone else you know accidentally swallows Podowart, contact your local poison control center and seek immediate medical attention. Keep out of small children's reach at all times. If you currently have any other skin conditions, are pregnant or nursing, have diabetes or circulatory issues, have sensitive skin, or any of the other conditions listed above, it may not be advisable for you to use this medication. Podophyllum resin is toxic when ingested.

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