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plaquenil side effects

In addition, lupus and rheumatoid arthritis are both treated with it. Certain kinds of malaria infections can be treated and prevented with the drug plaquenil.

Other names for this medication:

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To learn more, consult your physician or pharmacist. It is also approved for the treatment of rheumatoid arthritis and systemic lupus erythematosus (SLE). Several types of malaria can be prevented and treated with the prescription drug plaquenil. Other prescriptions for this medication are possible.


Over the course of three days, a total dose of 25 mg of base/kg is administered as follows: 10 mg base/kg as the first dose, followed by 5 mg base/kg six hours later, 5 mg base/kg 18 hours later, and 5 mg base/kg 24 hours later. Pay close attention to the instructions on your prescription label. It is preferable to administer medications to children (6 years of age and older) based on their body weight. Lupus Erythematosus The recommended initial dosage of hydroxychloroquine (Plaquenil) for the treatment of lupus erythematosus is 400 mg once or twice daily. Adults should take 400 mg of hydroxychloroquine (Plaquenil) on the exact same day each week to suppress malaria. Two weeks prior to exposure, suppressive therapy should start. Take this medication exactly as prescribed by your doctor. The dosage for adults may also be determined by body weight. The dosage your doctor prescribes for you may depend on the following factors: the condition being treated; other medical conditions you have; other medications you are taking; how you respond to this medication; your weight; your age; your kidney function; and your liver function. Rheumatoid Arthritis The initial dosage of hydroxychloroquine (Plaquenil) is recommended for the treatment of rheumatoid arthritis and ranges from 400 to 600 mg per day. For the treatment of lupus erythematosus, hydroxychloroquine (Plaquenil) maintenance doses of 200 to 400 mg per day are advised. The recommended maintenance dose range of hydroxychloroquine (Plaquenil) for the treatment of rheumatoid arthritis is 200 to 400 mg daily. For children aged 6 and older, the weekly suppressive dose of hydroxychloroquine (Plaquenil) is 5 mg base/kg. For eight weeks after leaving the endemic area, the suppressive therapy should be continued. Regardless of body weight, this dose should not go over the recommended adult dosage. On each of the following two days, 400 mg are then taken. Adults who have malaria are advised to take 800 mg of hydroxychloroquine (Plaquenil), followed by 400 mg in six to eight hours. Give an initial loading dose of 800 mg to adults when it is not given prior to exposure, or 10 mg base/kg to children when given in two divided doses spaced six hours apart.

Missed dose

If you miss a dose, call your doctor for instructions.


Call your doctor or the local poison control center immediately if you take too much Plaquenil, or go to the hospital for immediate emergency care.

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Side effects

For medical guidance on side effects, call your doctor. Common side effects include: headache dizziness loss of appetite nausea diarrhea stomach pain vomiting nervousness rash Tell your doctor if you have any side effect that bothers you or does not go away. Consult your physician or pharmacist for more details. These are not all of Plaquenil's potential side effects. Contact the FDA at 1-800-FDA-1088 to report side effects.


Not all possible drug interactions are listed here. Serious heart issues may result from plaquenil use. Drug interactions for plaquenil (more information) Tell your doctor about all your other medicines, especially: Other drugs, including over-the-counter drugs, prescription drugs, vitamins, and herbal remedies, may interact with hydroxychloroquine; the list provided here is not exhaustive. If you also take medication for cancer, malaria, HIV, depression, asthma, heart disease, high blood pressure, or other conditions, your risk may be increased. cimetidine; cyclosporine; methotrexate; praziquantel; tamoxifen; heart rhythm medicine; insulin or oral diabetes medicine; or seizure medication.


All patients on long term therapy should be questioned and examined periodically, including the examination of skeletal muscle function and tendon reflexes, testing of knee and ankle reflexes, to detect any evidence of muscular weakness. Drive carefully and abstain from operating machinery until you know how Plaquenil affects you. Plaquenil should not be taken if you have any of the following conditions: an allergy to Plaquenil or any of its ingredients; retinopathy of the eye already exists; use in children younger than 6 years old (200 mg tablets not adapted for weight 35kg); If weakness occurs, your doctor may need to discontinue the drug. minimal blood counts. Blurred vision and vertigo are side effects of plaquenil. Tell your doctor right away if you experience any of the following heart failure symptoms: breathlessness, swelling of the legs, an irregular heartbeat, fatigue, dizziness, or retinal damage. Plaquenil can cause the heart muscle to weaken, which can lead to heart failure. The retina—the part of the eye that produces vision—may sustain irreparable damage as a result of plaquenil. Serious side effects have been reported with Plaquenil including the following: Heart failure. If you experience any of the following symptoms, contact your doctor right away: blurred vision, seeing haloes around lights (especially at night), seeing light flashes and streaks, losing your visual field, changing the color of your eyes, having trouble focusing, difficulty reading (skipping words), night blindness, hypoglycemia (low blood sugar). If you experience any, all, or any combination of the following: sweating, shakiness, weakness, dizziness, rapid heartbeat, or muscular weakness, contact your healthcare provider right away. You are required to have an eye exam before taking Plaquenil, then a follow-up as often as needed while taking Plaquenil. Your doctor will keep an eye on your blood counts, and depending on the results, may have to stop the medication.

What is the difference between Plaquenil and hydroxychloroquine?

Hydroxychloroquine is used in the treatment of arthritis to help relieve inflammation, swelling, stiffness, and joint pain and also to help control the symptoms of lupus erythematosus (lupus; SLE). A common brand name for hydroxychloroquine is Plaquenil®.

What medicine can be substituted for Plaquenil?

Types of antimalarials Hydroxychloroquine (Plaquenil) is the most common antimalarial for lupus. If you can't take hydroxychloroquine, your doctor may recommend chloroquine (Aralen®). These medicines can be taken as pills or liquids.

An Update: Is hydroxychloroquine effective for COVID-19?

Multiple public health organizations, including the FDA, NIH and WHO have halted emergency use or study of hydroxychloroquine for COVID-19.

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Kenneth Ito Nov 19, 2013, 8:36:39 AM

Side effects of antimalarials Most people don’t notice any side effects, but antimalarials sometimes cause stomach pain and digestive problems, like nausea or diarrhea. It usually takes 1 to 3 months to start working. Doctors use antimalarials to treat malaria, but these medicines can also treat lupus by: Reducing pain and inflammation Preventing lupus flares and helping with lupus skin problems Lowering the dose (amount you need to take) of your other lupus medicines Most people with lupus take hydroxychloroquine throughout their lives. Hydroxychloroquine may also help prevent blood clots and organ damage from lupus. Types of antimalarials Hydroxychloroquine (Plaquenil) is the most common antimalarial for lupus.

Taras M Dec 12, 2018, 7:09:34 AM

It’s been used since the 1940s to prevent and treat malaria, and to treat rheumatoid arthritis and lupus. It’s sold in generic form and under the brand name Plaquenil in the United States. Doctors also can prescribe it off label for other purposes, as many are doing now for COVID-19. Some politicians and doctors are sparring over whether to use Hydroxychloroquine against the new coronavirus, with many scientists saying the evidence is too thin to recommend it now.

nano Dec 2, 2013, 10:36:22 AM

My husband and I spent an afternoon moving him into my office. I texted my brother and sister, explaining what I just witnessed. For a moment, I caught a glimpse of our new normal and had a sense it might be okay.

yume amethyst Mar 11, 2021, 6:05:33 PM

Plaquenil 200mg tablet is used for treating and preventing malaria which is caused by mosquito bites. What precautions should I take when taking Plaquenil 200mg Tablet (Generic Equivalent)? In the case of children, the dosage is provided based on weight. So, before you start taking medicine, make sure you consult with your doctor.

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