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Olanzapine
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olanzapine 5mg

Atypical antipsychotic; similar in structure to clozapine, but reduced incidence of EPS, hyperprolactinemia, neutropenia The product labels state that there is a boxed warning regarding an increased risk of suicidality in children, adolescents, and young adults as well as an increased mortality risk in elderly patients receiving treatment for dementia-related psychosis. the extended-release IM depot (Zyprexa Relprevv) is for maintenance treatment of schizophrenia in adults; the IM solution formulation (Zyprexa IntraMuscular) treats acute agitation associated with schizophrenia and bipolar disorder; and the extended-release IM depot (Zyprexa IntraMuscular) is an effective adjunct to fluoxetine for treatment-refractory depression or for depressive episodes of bipolar I disorder in adults. Used for the treatment of schizophrenia and for manic or mixed episodes of bipolar I disorder (as monotherapy or in combination with lithium or valproate) in both adults and adolescents; also used for maintenance treatment

Other names for this medication:
Zalasta, Olazax, Lybalvi, Zyprexa, Symbyax, Zypadhera

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Risnia, Zoloft, Nortriptyline, Seroquel, Prozac, Doxepin, Pexep, Citalopram, Cymbalta, Strattera, Bupron

Description

In comparison to the other dopamine receptor isotypes, olanzapine exhibits a higher affinity for the dopamine D2 receptor based on the specific mechanism of action. In clinical trials for its initial use, olanzapine was found to be significantly effective in treating bipolar disorder and schizophrenia in adults as well as acute manic or mixed episodes linked to bipolar disorder in adolescents. Olanzapine can significantly improve overall control of nausea and vomiting, as demonstrated by a number of clinical trials that have been conducted for this effect. In a high-level study of the effect of olanzapine for this condition, a complete response on the delay phase was observed in 84% of the individual and control of emesis of over 80% despite the phase. As opposed to this, its impact on the serotonin 5HT2A receptor delays the onset of anhedonia, flat affect, alogia, avolition, and poor attention. According to reports, olanzapine acts on the D2 receptor to produce the drug's beneficial effects, which include a reduction in hallucinations, delusions, disorganized speech, disorganized thought, and disorganized behavior. Olanzapine's impact on dopamine and serotonin receptors has been theorized to lessen chemotherapy-related nausea and vomiting because those receptors are thought to be involved in the process. This quality greatly reduces the likelihood of side effects.

Dosage

Daily dosage may subsequently be adjusted on the basis of individual clinical status within the range of 5-20 mg daily. Dosage greater than 10 mg daily only after reassessment. only after reevaluation, doses greater than 15 mg. 20 mg per day is the maximum dose. Initial 15 mg once daily monotherapy for mania. Schizophrenia, combination therapy for mania, and bipolar disorder: The starting dose is 5–10 mg once daily.

Missed dose

If you miss a dose, don't take a second one to make up for it. Skip the missed dose and carry on with your regular dosing schedule, though, if it is almost time for the subsequent dose. When you remember, immediately take the missed dose.

Overdose

Overdose symptoms may include drowsiness, agitation, aggression, slurred speech, confusion, increased heart rate, jerky or uncontrolled muscle movements, trouble breathing, or fainting. Call 1-800-222-1222 for poison help if you need immediate medical attention.

Storage

Speak with your pharmacy or the regional waste management firm. Unless specifically instructed to do so, never flush or pour medications down the drain. Do not store in the bathroom. Keep kids and pets away from all medications. When it is no longer needed or has expired, properly dispose of this product. Store at room temperature away from light and moisture.

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Side effects

If you experience any strange side effects while taking this medicine, contact your doctor right away. You or your doctor can submit a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online at http://www.fda.gov/Safety/MedWatch or by phone at 1-800-332-1088 if you experience a serious side effect. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section or the SPECIAL PRECAUTIONS section, call your doctor immediately: dizziness, feeling unsteady, or having trouble keeping your balance restlessness unusual behavior depression difficulty falling asleep or staying asleep weakness difficulty walking constipation weight gain dry mouth pain in arms, legs, back, or joints breast enlargement or discharge late or missed menstrual periods decreased sexual ability seizures changes in vision swelling of the arms, hands, feet, ankles, or lower legs unusual movements of your face or body that you cannot control falling sore throat, fever, chills, and other signs of infection very stiff muscles excess sweating fast or irregular heartbeat rash that may occur with fever, swollen glands, or swelling of the face skin redness or peeling hives difficulty breathing or swallowing Olanzapine may cause other side effects. Olanzapine might have adverse effects. The amount of fat in your blood may rise if you take olanzapine. The risks of treating your child with olanzapine should be discussed with your child's physician. The risks of taking olanzapine should be discussed with your doctor. Teenagers taking olanzapine are more likely than adults to gain weight, have higher blood fat levels, experience liver issues, and have side effects like sleepiness, breast enlargement, and discharge from the breasts. Tell your doctor if any of these symptoms are severe or persistent, including dizziness, unsteadiness, or trouble maintaining balance, restlessness, unusual behavior, depression, difficulty falling or staying asleep, weakness while moving around, constipation, weight gain, dry mouth, late or missed periods, decreased sexual ability, seizures, changes in vision, swelling of the hands, feet, arms, or breasts. A different drug without these risks might be suggested as a first step by your child's doctor.

Interactions

Injurious CNS effects and orthostatic hypotension may be amplified by alcohol. Don't drink. Take with or without food. Food has no impact on how well olanzapine is absorbed.

Contraindications

Also tell your doctor if you have ever had to stop taking a medication for mental illness because of severe side effects. tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breastfeeding. Be sure to mention any of the following: antidepressants; antihistamines; carbamazepine (Tegretol); dopamine agonists such as bromocriptine (Parlodel), cabergoline (Dostinex), levodopa (Dopar, Larodopa), pergolide (Permax), and ropinirole (Requip); fluoroquinolone antibiotics including ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the United States), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), others; fluvoxamine (Luvox); ipratropium (Atrovent); medications for anxiety, high blood pressure, irritable bowel disease, mental illness, motion sickness, Parkinson's disease, seizures, ulcers, or urinary problems; omeprazole (Prilosec); rifampin (Rifadin); sedatives; sleeping pills; ticlopidine (Ticlid); and tranquilizers. Inform your doctor and pharmacist what prescription and nonprescription drugs, vitamins, dietary supplements, and herbal products you are taking or plan to take before beginning olanzapine, if you have any allergies to it or any other medications. You should be aware that you may experience hyperglycemia (increases in your blood sugar) while taking this medication, even if you do not already have diabetes, and that smoking cigarettes may reduce the effectiveness of this medication. While taking olanzapine, refrain from consuming alcohol, and let your doctor know if you smoke. You should be aware that alcohol can increase the drowsiness brought on by this medication, so you should not drive a car or operate machinery until you know how it affects you. Call your doctor right away if you get pregnant while taking olanzapine. You are more likely to develop diabetes if you have schizophrenia than you are if you don't, and taking olanzapine or other similar drugs may make you more likely to develop diabetes if you already have the disorder. Calling your doctor as soon as you experience any of these symptoms is crucial because high blood sugar can result in the serious condition known as ketoacidosis. If ketoacidosis is not treated right away, it could become life-threatening. Ensure that your child complies with all directions from the therapist or doctor. If olanzapine is taken during the final months of pregnancy, it may cause problems for newborns after delivery. If you are having surgery, including dental surgery, let your doctor or dentist know that you are taking olanzapine. You should be aware that olanzapine may cause fast or slow heartbeat, dizziness, lightheadedness, and fainting when you get up quickly from a lying position. Symptoms of ketoacidosis include dry mouth, nausea, vomiting, shortness of breath, breath that smells fruity, and decreased consciousness. Inform your doctor right away if you have constipation, severe vomiting or diarrhea, or any other symptoms of dehydration, or if these symptoms start to appear at any point while you are receiving treatment. If you have phenylketonuria (PKU, an inherited condition requiring a special diet to prevent damage to your brain that can cause severe intellectual disability), you should be aware that the orally disintegrating tablets contain aspartame, which converts to phenylalanine. you should also be aware that olanzapine must be used as part of a comprehensive treatment program when treating teenagers. While taking olanzapine, if you experience any of the following symptoms, contact your doctor right away: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. This is more common when you first start taking olanzapine. You should be aware that olanzapine may make it harder for your body to cool down when it gets very hot, so get out of bed slowly and rest your feet on the floor for a few minutes before standing up to prevent this issue. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you use or have ever used street drugs or have overused prescription medications and if you have or have ever had a stroke, a mini-stroke, heart disease or a heart attack, an irregular heartbeat, heart failure, urinary problems, seizures, breast cancer, any condition that makes it difficult for you to swallow, trouble keeping your balance, high or low blood pressure, a high level of fats (cholesterol and triglycerides) in your blood, a low number of white blood cells, liver or prostate disease, paralytic ileus (condition in which food cannot move through the intestine); glaucoma (an eye condition), or high blood sugar, or if you or anyone in your family has or has ever had diabetes.

What is olanzapine used for?

Olanzapine is used to treat schizophrenia. It may also be used alone or with other medicines (eg, lithium or valproate) to treat mania or mixed episodes that is part of bipolar disorder (manic-depressive illness).

Can I drink alcohol with it?

It’s best not to drink alcohol for the first few days of treatment, until you see how the medicine affects you. If you drink alcohol while taking olanzapine it may make you feel sleepy and unsteady on your feet. Drinking alcohol every day or in large amounts can make your symptoms worse. It also makes it harder for olanzapine to work properly.

What is the major side effect of olanzapine?

Common side effects of olanzapine may include: tremors or shaking, numbness or tingly feeling; changes in personality; dry mouth, or increased salivation; stomach pain, constipation; or.

Is olanzapine a sleeping pill?

3. Is olanzapine a sleeping pill? Olanzapine is not a sleeping pill and should not be prescribed for sleep disturbances. The medicine is a potent antipsychotic drug that is used for the treatment of schizophrenia and bipolar disorder.

What is olanzapine 10 mg tablet used for?

Olanzapine is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in adults and teenagers 13 years of age and older.

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Testimonials
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Tawhid Qurishe Apr 6, 2019, 10:23:00 PM

Since the orodispersible tablet is fragile, it should be taken immediately on opening the blister. The recommended starting dose for olanzapine is 10 mg/day. A greater magnitude of weight gain, lipid and prolactin alterations has been reported in short term studies of adolescent patients than in studies of adult patients (see sections 4.4, 4.8, 5.1 and 5.2). Olanzapine orodispersible tablet should be placed in the mouth, where it will rapidly disperse in saliva, so it can be easily swallowed. In cases where dose increments of 2.5 mg are considered necessary, other olanzapine pharmaceutical forms should be used.

Loris Brandimarte Sep 12, 2019, 1:55:35 PM

Do not start or stop any medicine while taking olanzapine tablets without talking to your doctor first. Teenagers (13 to 17 years old) are more likely to gain weight and to gain more weight than adults. High fat levels may happen in people treated with olanzapine tablets, especially in teenagers (13 to 17 years old).

Karinka325 Apr 13, 2019, 7:13:28 AM

It functions by assisting in the restoration of the equilibrium of certain natural chemicals in the brain. Constipation Dizziness Blurred vision Nervousness Sedation Weight gain Contact for Olanzapine and Fluoxetine Tablets Manufacturing and Supply Neurocon is a well known pharma company that deals with the quality of neuro products. Olanzapine and Fluoxetine Tablets should be taken after taking a meal and before going to bed as it causes sleepiness so taking in day time may divert one’s mind from usual tasks. It is also used to treat depression in patients who have not responded to other medicines. We provide a large selection of DCGI and FSSAI certified goods at extremely low rates.

Nurla Dec 15, 2016, 10:00:03 AM

The starting dose is 15mg as a single daily dose in monotherapy or 10mg daily in combination therapy (see section 5.1). A greater magnitude of weight gain, lipid and prolactin alterations has been reported in short-term studies of adolescent patients than in studies of adult patients (see sections 4.4, 4.8, 5.1 and 5.2). The starting dose and dose range need not be routinely altered for non- smokers relative to smokers.The metabolism of olanzapine may be induced by smoking. A lower starting dose (5mg/day) is not routinely indicated but should be considered for those 65 and over when clinical factors warrant (see section 4.4).

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