Side effects
A medication may also have some unintended side effects in addition to its desired effects. Even though not all of these side effects are likely to occur, if they do, medical attention may be required. Immediately consult your doctor or a nurse if any of the following side effects manifest themselves: Skin cracks, heat loss from the body, red, swollen skin, and scaly skin Incidence not known Rare
Interactions
When combined with amodiaquine or quinine for the treatment of multi-drug resistant Plasmodium falciporum infections. When used to treat infections brought on by susceptible anaerobic bacteria or susceptible strains of gram positive bacteria like Streptococci, Staphylococci, and Pneumococci, clindamycin has been shown to be effective: upper respiratory infections, lower respiratory infections, skin and soft tissue infections, bone and joint infections, pelvic infections, intra-abdominal infections, septicemia and endocarditis, and dental infections.
Contraindications
Ask your pharmacist for a list of the ingredients. Make sure to list the following medications: erythromycin (E.E.S., E-Mycin, Erythrocin, others), indinavir (Crixivan), itraconazole (Sporanox), ketoconazole (Nizoral), nefazodone, nelfinavir (Viracept), rifampin (Rifadin, in Rifamate, in Rifater, Rimactane), Before taking clindamycin, tell your doctor and pharmacist if you are allergic to clindamycin, lincomycin (Lincocin), any other medications, or any of the ingredients in clindamycin capsules or solution. Call your doctor if you become pregnant while taking clindamycin, and let them know if you're having surgery, including dental work, if you're taking clindamycin. If you will be taking clindamycin capsules, tell your doctor if you are allergic to aspirin or tartrazine (a yellow dye found in some medications). tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Many other medications may also interact with clindamycin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. tell your doctor if you have or have ever had asthma, allergies, eczema (sensitive skin that often becomes itchy or irritated) or kidney or liver disease. tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. The dosage of your medications may need to be adjusted, and your health may need to be closely watched for any side effects.
Avoid exposing the treated areas of skin to excessive sunlight, or to sunbeds or sunlamps. It should be used with caution during pregnancy, and only if the benefits to the mother outweigh any potential risks to the developing baby. Rita Ghelani (BPharm, MRPharmS) Pharmacist A UK registered practising pharmacist with over 20 years' experience, Rita is a member of the medical journalists’ association (MJA) and has a wealth of experience in community pharmacy. Duac gel should not be used for longer than 12 weeks at a time.
Clindamycin is systemically administered as capsules or injections for most infections, but topical formulations and vaginal preparations can be used for intravaginal or local applications on the skin. Oxygen is toxic to anaerobic bacteria, while aerobic bacteria can grow in the presence of oxygen because they produce enzymes that detoxify oxygen. Gram-negative bacteria have an additional membrane outside the cell wall that gram-positive bacteria lack.
Many drugs are commonly prescribed for off label use in veterinary medicine. Are there any drug interactions I should be aware of? What if I miss giving my pet the medication or my shipment is late? Its use to treat certain infections, such as toxoplasmosis, is ‘off label’ or ‘extra-label’.
It reduces growth of bacteria by interfering with their ability to make proteins. The FDA approved clindamycin vaginal suppositories in November, 2004. Clindamycin vaginal cream is indicated for the treatment of bacterial vaginosis (formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, Corynebacterium vaginitis, or anaerobic vaginosis) in non-pregnant women. Clindamycin in general is an antibiotic used for treating several other infections as well.
If you have been told to use clindamycin injection at home, it is very important that you use the medication exactly as directed. It is usually given two to four times a day. The length of your treatment depends on the type of infection you have and how well you respond to the medication. Use clindamycin injection until you finish the prescription, even if you feel better.