Information on nimodipine that has been reviewed by a doctor, including its description, dosage, and instructions.
Other names for this medication:
Nymalize, Nimotop
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Hydrochlorothiazide, Lisinopril, Cordarone, Warfarin, Amiodarone, Digoxin
Nimodipine's high lipophilicity causes it to act more strongly on the cerebral vessels. Nimodipine relaxes the smooth muscle of the vascular system and the myocardium during depolarization by preventing the entry of calcium ions into cells by blocking calcium channels or specific voltage-sensitive areas.
For more information, speak to your doctor or pharmacist. If your doctor or pharmacist says it's safe for you to do so, avoid consuming grapefruit or grapefruit juice while taking this medication. Consult your doctor or pharmacist for details. Do not crush. This medication should not be injected. After taking this medication, avoid lying down for at least 10 minutes. The capsule's contents should not be combined with other liquids. Without first consulting your physician, don't stop taking this medication abruptly. Do not use a household spoon because you may not get the correct dose. Thus, the medication might stop working. Follow your doctor's directions carefully. The risk of this medication's side effects can increase when grapefruit is consumed. Inquire with your healthcare provider for specific directions on how to administer this medication if you're using a nasogastric or gastric tube. If you are taking the capsule form of this medication, take it by mouth as directed by your doctor. Unless your doctor instructs you otherwise, take this medication by mouth with a full glass of water (8 ounces/240 milliliters) if you are taking the tablet form. When using this medication's liquid form (oral solution), measure the dosage precisely using a specialized measuring tool or spoon. If you can't swallow a capsule whole, you can pierce it, syringe the liquid out, and then administer it orally or through a nasogastric tube. If you have any questions, ask your doctor or pharmacist. Even if you feel fine and even if you don't notice a change in your symptoms, keep taking this medication. Nimodipine should be taken as prescribed by your doctor, typically every 4 hours, one hour prior to or two hours following a meal. Read the Patient Information Leaflet if available from your pharmacist before you start taking nimodipine and each time you get a refill. See also Warning section. Some brands of this medication may come in a prefilled oral syringe with the exact dose. Wholeheartedly ingest the capsule. Take the tablet whole. Tell your doctor if your condition worsens. The dosage is determined by your health status and treatment response. The liquid form can also be administered via gastric or nasogastric tube into the stomach. This medication is started as soon as possible, usually four days after the first signs of brain bleeding. Usually, 2 to 4 weeks are needed to finish this medication. Take it at the same times every day to help yourself remember. Use this medication regularly to get the most benefit from it. If the medication is stopped too soon, your condition might get worse.
To catch up, don't double the dose. You should skip the missed dose if it is almost time for your next dose. Take the missed dose as soon as you remember if you forget. At the scheduled time, take your subsequent dose.
If you take too much nimodipine, call your doctor or the nearest poison control center right away, or go to the hospital for emergency care.
Protect from light. Keep things at 15 to 30 °C.
For more information, speak with your doctor or pharmacist. For medical guidance on side effects, call your doctor. Refer to the "Drug Precautions" section. Nimodipine has been linked to severe side effects. The following are some of the side effects of nimodipine that have been most frequently reported in clinical trials: rash decreased blood pressure headache nausea dizziness Call 1-800-FDA-1088 to report side effects to the FDA.
Many medications can interact with nimodipine, and some medications shouldn't be taken at the same time. More information on nimodipine Adverse reactions Drug interactions Dosage guidance Pregnancy and breastfeeding information Reviews (3) Drug images Comparative pricing & coupons Spanish Drug class: calcium channel blocking agents Patient resources Advanced Reading Nimodipine Capsules Nimodipine Oral Solution Other brands Nimotop, Nymalize Professional resources Prescribing Information Related treatment manuals Subarachnoid Hemorrhage Ischemic Stroke Migraine Prevention Nimodipine drug interactions (more detail) The interactions here are not all possible interactions. Other medications you take may have their blood levels affected by some drugs, which could increase their side effects or reduce their efficacy. It is occasionally dangerous to take certain medications at the same time. In addition to any new or discontinued medications, make sure your doctor is aware of all of your current medications. This covers both prescription and non-prescription drugs, vitamins, and herbal products.
Call your doctor right away if you have cirrhosis (liver scarring). Until you know how nimodipine affects you, do not operate machinery or drive a car. Hypotension, or low blood pressure, may cause you to feel faint or dizzy. Additionally, an excessive drop in blood pressure can be brought on by inadequate hydration, excessive perspiration, diarrhea, or vomiting. If you feel faint or lightheaded, lie down. Nimodipine has the potential to make you feel lightheaded. Serious side effects are more likely to affect people who have already been diagnosed with cirrhosis. In addition to hypotension, nimodipine has been linked to serious side effects. A smaller dose of nimodipine may be prescribed by your doctor while closely monitoring blood pressure and pulse rate.
When should nimodipine be given?
Nimodipine comes as a capsule and an oral solution (liquid) to take by mouth or be given through a feeding tube. It is usually taken every 4 hours for 21 days in a row. Treatment with nimodipine should be started as soon as possible, no later than 96 hours after a subarachnoid hemorrhage occurs.
When should you hold nimodipine?
medications counts if nimodipine (i.e., Nimotop, Nymalize) was on order at the time of the notation. EXCEPTION: Documentation of a conditional hold or discontinuation of nimodipine (e.g., “Hold nimodipine if SBP < 100 mm/Hg”, “Stop nimodipine if AST > 50 IU/L”.
When do you administer nimodipine?
Nimodipine comes as a capsule and an oral solution (liquid) to take by mouth or be given through a feeding tube. It is usually taken every 4 hours for 21 days in a row. Treatment with nimodipine should be started as soon as possible, no later than 96 hours after a subarachnoid hemorrhage occurs.
Why nimodipine is used in subarachnoid hemorrhage?
Nimodipine is used to decrease problems due to a certain type of bleeding in the brain (subarachnoid hemorrhage-SAH). Nimodipine is called a calcium channel blocker. The body naturally responds to bleeding by narrowing the blood vessel to slow blood flow.
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Monitor therapy Tocilizumab: May decrease the serum concentration of CYP3A4 Substrates (High risk with Inducers). Monitor therapy Simeprevir: May increase the serum concentration of CYP3A4 Substrates (High risk with Inhibitors). Management: The maximum recommended dosage of lemborexant is 5 mg, no more than once per night, when coadministered with weak CYP3A4 inhibitors. Monitor therapy Methylphenidate: May diminish the antihypertensive effect of Antihypertensive Agents.
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OBJECTIVES The primary objective was to determine the prescribing incidence of a nonstandard nimodipine dosing regimen (30 mg every 2 h) after… However, hypotension is an adverse effect of nimodipine and is believed to prompt clinicians to prescribe an unproven, nonstandard nimodipine dosing regimen. BACKGROUND Aneurysmal subarachnoid hemorrhage is a significant cause of death and disability. Nimodipine 60 mg administered enterally every 4 h improves neurologic outcomes in these patients.
Cortisone acetate (brand names Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others) is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed in many countries throughout the world, including in the United States, the United Kingdom, and various other European countries. It is the C21 acetate ester of cortisone, and acts as a prodrug of cortisone in the body.