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Headaches and nausea are frequent side effects of Nexium. It belongs to a class of drugs called proton pump inhibitors. Nexium (esomeprazole) is a medication available only by prescription that is used to treat GERD, ulcers, and other conditions linked to stomach acid. Nexium can cause serious side effects like kidney damage and bone fractures.

Other names for this medication:
Vimovo, Esomeprazole

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Additionally, it is used to speed up the recovery from erosive esophagitis, which is esophageal damage brought on by stomach acid. Proton pump inhibitors like Nexium reduce how much acid is produced in the stomach. The immediate relief of heartburn symptoms is not a goal of Nexium. The symptoms of Zollinger-Ellison syndrome and other conditions involving excessive stomach acid are treated with Nexium. GERD is one of these conditions. Nexium may also be given to prevent gastric ulcer caused by infection with Helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).


Ask your doctor or pharmacist if you do not understand these instructions. If, while taking this medication, your symptoms do not disappear or worsen, contact your doctor right away. Specific dosage details for Nexium A delayed-release capsule should not be chewed or crushed. Do not save the mixture for later use. Typically, esomeprazole is only prescribed for 4 to 8 weeks. Open the capsule, however, and add the medication to a spoonful of pudding or applesauce to make swallowing easier. At least an hour before a meal is recommended for taking Nexium. Read and carefully follow any Instructions for Use provided with your medicine. Esomeprazole and antibiotics are used together to treat some conditions. Store at room temperature away from moisture and heat. Without chewing, immediately swallow. Take each dose with a full glass (8 ounces) of water. Mention that you take esomeprazole to any medical professional who treats you. The capsule can be given through a nasogastric (NG) feeding tube. This medicine can affect the results of certain medical tests. Follow the instructions on the Nexium label exactly, or use it as your doctor has advised. Use all medications as directed. Even if your symptoms disappear quickly, take this medication for the full recommended period of time. In the event that you require more time for healing, your doctor might suggest a second round of therapy.

Missed dose

Do not use two doses at one time. If it is almost time for your next dose, skip the missed dose and use the medication as soon as you can.


However, seek immediate medical attention if overdose is thought to have occurred. An overdose is unlikely to happen if Nexium is administered by a healthcare professional in a hospital setting. If you take too much Nexium, call your neighborhood poison control center or get immediate medical help.

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Side effects

If you experience any of the following: Call your physician for advice on possible side effects. Typical adverse effects of Nexium include: If you experience any of the following symptoms of an allergic reaction to Nexium: hives, difficulty breathing, swelling of your face, lips, tongue, or throat, seek emergency medical attention. A vitamin B-12 deficiency might occur if you take esomeprazole for more than three years. Nexium side effects (more detail) Fundic gland polyps are stomach growths that can appear after taking esomeprazole for a long time. If you experience this condition, discuss treatment options with your doctor. Consult your doctor about this risk. Other side effects could occur; this is not a comprehensive list. Call 1-800-FDA-1088 to report side effects to the FDA. diarrhea; stomach pain; nausea; constipation; or dry mouth. severe stomach pain, watery or bloody diarrhea, seizure (convulsions), kidney problems (fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, weight gain), low magnesium (dizziness, fast or irregular heartbeat, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling), or


To learn more, consult your physician or pharmacist. Especially tell your doctor if you take: warfarin (Coumadin, Jantoven) ketoconazole (Nizoral) voriconazole (Vfend) atazanavir (Reyataz) nelfinavir (Viracept) saquinavir (Fortovase) products that contain iron digoxin (Lanoxin, Lanoxicaps) St.John’s Wort (Hypericum perforatum) Rifampin (Rimactane, Rifater, Rifamate) cilostazol (Pletal) diazepam (Valium) tacrolimus (Prograf) Erlotinib (Tarceva) Methotrexate clopidogrel (Plavix) This is not a complete list of Nexium drug interactions. Both the effects of Nexium and the effects of other medications are possible. Tell your doctor about all of the medicines you take including prescription and non-prescription drugs, vitamins and herbal supplements.


Fractures in bones. If you have diarrhea, stomach pain, or a fever that won't go away, call your doctor right away. If you are allergic to any of the ingredients in Nexium or to any other Proton Pump Inhibitor (PPI) medications, you should not take Nexium. If low magnesium levels do occur, it usually does so a year into treatment. Some people who take a proton pump inhibitor for at least three months may experience low magnesium levels. Nexium can cause serious allergic reactions. Nexium may increase your risk of getting severe diarrhea. Proton Pump Inhibitor users who take multiple daily doses for a long time (a year or more) may be at higher risk for hip, wrist, or spine fractures. Diarrhea is one of the serious side effects of Nexium that have been reported. Discuss with your doctor the possibility of a bone fracture if you take Nexium. Tell your doctor if you get any of the following symptoms: Low magnesium levels in your body. Tell your doctor right away if you experience any of the following symptoms: rash face swelling throat tightness difficulty breathing seizures dizziness abnormally fast heartbeat jitteriness jerking movements or shaking (tremors) muscle weakness spasms of the hands and feet cramps or muscle aches spasm of the voice box Your doctor may check the level of magnesium in your body before you start taking Nexium or during treatment if you will be taking Nexium for a long time. Your intestines' Clostridium difficile infection could be the source of this diarrhea. This issue could be very serious. There's a chance that you don't have low magnesium symptoms. You should take Nexium exactly as prescribed, at the lowest dose possible for your treatment and for the shortest time needed.

Are zoton and Nexium the same?

Proton pump inhibitors (known in Australia by names such as Nexium, Pariet, Losec, Somac and Zoton) work by preventing key pumps in the cells of the stomach that produce stomach acid from working. In stopping the production of stomach acid they help to reduce the inflammation and heal ulcers caused by the stomach acid.

Why should you not take Nexium?

FDA Warnings About Nexium Past warnings have included: Bone fractures, low magnesium levels, clostridium difficile-associated diarrhea, vitamin B12 deficiency, acute interstitial nephritis, potential fetal harm, and the risk of new or worsening lupus.

What is the difference between Nexium and esomeprazole?

Esomeprazole (Nexium) and esomeprazole strontium are both used to treat similar stomach conditions, but they are not the same medication. The two medications contain different chemicals; esomeprazole (Nexium) contains magnesium, whereas esomeprazole strontium contains strontium.

What exactly does Nexium do?

It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Esomeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).

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Prerna Jain Feb 24, 2013, 7:52:53 PM

Concerns over long-term exposure of Nexium surfaced once again when a study published in May 2016 in the Circulation Research raised questions about faster aging of blood vessels due to PPIs like Nexium. In one study, medical records of over 173,000 subjects who were prescribed a PPI drug were compared to more than 20,000 who were given a different class of heartburn drugs, known as H2-blockers. Nexium and other PPIs have been reported to have a high risk of kidney injuries, including acute interstitial nephritis, kidney/renal failure, and chronic kidney disease (CSK).

flyx Jun 29, 2011, 12:49:26 PM

JAMA report In January of 2016 the Journal of the American Medical Association found that the risk of chronic kidney disease increased anywhere from 20-50 percent when taking Nexium. Continued litigation While there has been Nexium lawsuit settlement in several individual and class action suits, others are being initiated on practically a daily basis. While the litigation filed against AstraZeneca has been dismissed by some as being without merit, the typical Nexium lawsuit is anything but frivolous.

Aaron Thoma Apr 9, 2018, 3:04:09 PM

NastLaw is investigating claims of people that took brand name Nexium, Prilosec or Prevacid products and developed Chronic Kidney Disease or other serious kidney injuries. After the studies were published about the potential for serious kidney injuries from Nexium, Prilosec and Prevacid, our team of dangerous drug lawyers began investigating whether there were legal consequences for the manufacturers of these drugs. If you took one of these drugs and suffered a serious kidney injury you may be able to seek financial compensation through a Nexium Lawsuit, Prilosec Lawsuit, or Prevacid Lawsuit.

user2820800 Feb 18, 2012, 3:33:34 AM

Non devono essere usati altri liquidi in quanto il rivestimento gastroresistente si potrebbe dissolvere. La co-somministrazione di esomeprazolo e atazanavir non è raccomandata (vedere paragrafo 4.5). Risultati provenienti da studi in volontari sani hanno mostrato un'interazione farmacocinetica (PK)/farmacodinamica (PD) tra clopidogrel (dose di carico 300 mg/dose di mantenimento giornaliera 75 mg) e esomeprazolo (40 mg per via orale al giorno) risultando in una diminuita esposizione al metabolita attivo di clopidogrel pari mediamente al 40%, e risultando in una diminuzione della inibizione massima dell'aggregazione piastrinica (ADP indotta) pari mediamente al 14%.

user22106 Sep 4, 2022, 7:45:19 AM

If any medication remains in the container, add more water, stir, and drink immediately to make sure you take the entire dose.Do not crush or chew the medication granules. GENERIC NAME: ESOMEPRAZOLE DELAYED-RELEASE SUSPENSION - ORAL (ES-oh-MEP-ra-zole) BRAND NAME(S): Nexium Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage USES: Esomeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. This medication may also be given through a tube into the stomach (nasogastric or gastric tube). Stir again and drink all of the mixture within 30 minutes.

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