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Oral therapy is primarily used for patients with severe, drug-resistant HTN due to high potency and significant adverse reactions. Topical therapy is used for alopecia.

Other names for this medication:
Rogaine, Loniten

Similar Products:
Nitroglycerin, Zebeta, Nebivolol, Beloc, Verapamil, Tritace, Diovan, Prinivil, Isoptin, Aldactone, Vasotec, Procardia, Lozol, Calan, Arpamyl


Approximately 95% of the drug that was systemically absorbed is eliminated within 4 days after topical dosing is stopped. Following topical application, the normal, intact scalp absorbs 1.4% of the total dose applied. The main method of excretion for minoxidil and its metabolites is urine. When blood vessels are widened and androgen hormone is inhibited to affect hair follicles, minoxidil promotes hair growth by increasing the supply of oxygen, blood, and nutrients to the hair follicle. The rate at which a drug is absorbed through the skin determines serum levels of Minoxidil and the systemic effects that follow topical Minoxidil administration. Topical Minoxidil absorption is increased by increasing the dose applied, increasing the frequency of dosing and decreasing the barrier function of the stratum corneum.


Without first consulting your doctor, do not stop taking this medication. Observe your doctor's instructions exactly. Ask your doctor or pharmacist any questions you may have. Also based on weight is the dosage for children. It may take several days to a couple of weeks before you get the full benefit of this drug. Keep taking your medications even if you feel well. Most people with high blood pressure do not feel sick. When you first start taking this medication and each time you get a refill, read the Patient Information Leaflet, if one is provided by your pharmacist. Some conditions may become worse when this drug is suddenly stopped. To get the most benefit from this medication and your other blood pressure medications, take them regularly. As prescribed by your doctor, usually once or twice a day, take this medication by mouth with or without food. If your condition does not improve or if it worsens (your blood pressure readings remain high or rise), let your doctor know. Your medical condition and treatment response will determine the appropriate dosage. Take them every day at the same time(s) to help you remember. Your physician might advise you to begin taking this medication at a low dose and gradually increase it. Perhaps you should gradually cut back on your dosage.

Missed dose

In order to catch up, do not double the dose. Skip the missed dose if it is almost time for the next dose. If you forget to take a dose, do so right away. At the scheduled time, take your next dose.


Call emergency services at 911 right away if the victim has fallen, experienced a seizure, is having trouble breathing, or cannot be roused. Dial 1-800-222-1222 to reach the poison control hotline in the event of an overdose. Additionally, information can be found online at


Ensure that children cannot access it. Store away from light in a cool, dry environment.

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Side effects

Call your doctor right away if you notice any of the following side effects, or any of those detailed in the IMPORTANT WARNING section. Breast tenderness, an increase in the size or darkness of fine body hair, a headache, nausea, vomiting, rash, a rapid heartbeat, swollen ankles or feet, an unexplained increase in weight, difficulty breathing, dizziness, or fainting. If you experience a serious side effect, you or your doctor may report it to the Possible negative effects of minoxidil. Tell your doctor if any of these symptoms are severe or do not go away: increase in size or darkness of fine body hair breast tenderness headache nausea vomiting rash fast heartbeat swollen ankles or feet unexplained weight gain difficulty breathing dizziness fainting Some side effects can be serious.


Minoxidil drug interactions (more information) More about minoxidil Side effects Drug interactions Dosage information During pregnancy or Breastfeeding Reviews (4) Drug images Pricing & coupons En español Drug class: vasodilators Patient resources Advanced Reading Minoxidil (Systemic) Other brands Loniten Professional resources Prescribing Information Related treatment guides High Blood Pressure Other medications, including prescription and over-the-counter drugs, vitamins, and herbal products, may interact with minoxidil. Give a list of all the medications you are currently taking, as well as any that you start or stop taking, to each of your healthcare providers.


The adverse effects of minoxidil may worsen if alcohol is consumed. Inform your doctor and pharmacist about all prescription and non-prescription drugs, vitamins, dietary supplements, and herbal products you are currently taking or plan to take. Be sure to mention any of the following: diuretics ('water pills'), guanethidine, and other medications for high blood pressure. tell your doctor if you have pheochromocytoma (adrenal gland tumor). Inform your doctor and pharmacist if you have any allergies prior to taking minoxidil, whether it be to the drug, any other medications, or any of the ingredients in the tablet form. Ask your doctor whether drinking alcohol is safe while taking minoxidil; until you know how it affects you, do not operate machinery or drive a car. If you become pregnant while taking minoxidil, call your doctor. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking minoxidil. you should know that this medication may make you drowsy. If you have recently experienced a heart attack, have heart or kidney disease, are pregnant, plan to become pregnant, or are nursing, your doctor will likely advise against taking minoxidil.

Can women use 5% minoxidil?

Abstract. Minoxidil is a Health Canada and US FDA-approved medication for hair loss in men and women. While 5% minoxidil foam has been approved for men since 2006, Health Canada and the FDA only approved 5% minoxidil foam for female pattern hair loss (FPHL) in 2014.

Is Rogaine and minoxidil the same?

Minoxidil is the generic form of Rogaine, so the active ingredient in the generic or name brand of Rogaine is the same.

Is minoxidil different for women?

Men's and women's Rogaine are marketed differently but contain the same ingredients. “I thought, maybe this is just a fluke,” says Lipoff, assistant professor of dermatology at the University of Pennsylvania Perelman School of Medicine. “But I went to a couple different stores and saw it was pretty consistent.”

Can minoxidil damage hair?

There is a lack of any benefit from topical Minoxidil after 6 months of diligent use. Topical Minoxidil causes poor hair texture – sometimes Minoxidil can cause dry, tangled hair that is prone to breakage. There are other difficulties using topical Minoxidil – and this causes compliance problems.

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Saranga Vimukthi Dec 7, 2017, 5:56:01 AM

As a consequence, in the 1960s and ’70s, it was developed as a treatment for high blood pressure (hypertension) (1). These may include hives, rash, difficulty breathing, and swelling of the lips, mouth, tongue, or throat. An Unexpected Side Effect Another unexpected use of the drug – discovered during initial trials – was its effectiveness in the treatment of hair loss.

Denchik1612 Jan 16, 2010, 6:47:54 PM

There are now also countless online forum testimonials with photos from men who have had success with this Rogaine beard growth experiment. Also see my 2013 post on Rogaine beard experiment. Side effects of using Minoxidil on the Face It should be noted that prolonged use of Minoxidil on Beards can cause a number of side effects, including: Skin irritation, including itchiness, rashes, dryness and inflammation. In such cases, we do not know which of the treatments is causing the most hair growth.

Eqbal Oct 1, 2010, 5:16:14 AM

The most popular of these are Walmart’s Equate brand and Costco’s Kirkland brand. To date, the main theories about how Minoxidil works to grow hair are: Due to its proliferative and vasodilatory actions. Rogaine Shedding Some people will shed a lot of hair after changing their Rogaine (Minoxidil) dosage. Minoxidil was first approved by the US FDA to treat male pattern baldness (MPB) in 1988. I regularly update this post with newer studies discussing this topical drug’s mechanism of action in stimulating hair growth.

Stefanski13 May 29, 2022, 6:32:58 AM

For better control and less dripping while applying, go mild and consider foam-based solutions. Peppermint Oil Menthol is one of the active elements in peppermint oil, encouraging hair regrowth. The potassium channels in vascular smooth muscle cells, sensitive to adenosine triphosphate (ATP), open when Minoxidil is administered as a vasodilator. Hence, it is also necessary to keep the face, beard area, and beard hair follicles hydrated. It signifies that a large number of people are affected.

410011091199309 Feb 18, 2021, 1:14:26 PM

It’s possible that new research could come out in the future showing that a stronger or weaker type of minoxidil may be more effective at preventing hair loss and promoting hair growth. Most minoxidil products use either a 5% minoxidil formula or a lower-strength formula that only contains 2% minoxidil. When used together, men saw better results in clinical trials compared to using either alone. After 12 months of treatment, 59 percent of the men treated with 5% minoxidil and 80.5 percent of the men treated with finasteride showed improvements. Biotin is a vitamin that plays an important role in the growth of your hair, skin and nails.

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