Side effects
For more information, speak with your doctor or pharmacist. Serious side effects from minocycline are possible. See "Drug Precautions" section. The most frequent side effects of minocycline are: nausea, fever, diarrhea, vomiting, exhaustion, headache, dizziness or spinning sensation, itching, and so on. Call your doctor if you experience any side effects that bother you or do not go away. Not all of minocycline's side effects are listed here. Your doctor may order tests to see if you are experiencing any side effects from your minocycline treatment.
Interactions
If you are unsure whether your medication is one of those listed above, consult your doctor or pharmacist. Especially tell your doctor if you take: birth control pills. Keep a list of them to show your doctor and pharmacist. Know the medicines you take. Use of isotretinoin and minocycline should not be combined. An anti-acne medication that contains isotretinoin (Amnesteem, Claravis, Sotret) that contains aluminum, calcium, magnesium, or iron should not be used in conjunction with minocycline. Minocycline may affect the way other medicines work, and other medicines may affect how minocycline works. Your birth control pills may be less effective if you take minocycline. Inform your doctor of every other medication you take, including vitamins, herbal supplements, prescription and over-the-counter drugs, and prescription and non-prescription medications. Possibility of getting pregnant. While taking minocycline, a blood thinner, or a penicillin antibiotic, you should use a second method of birth control.
Contraindications
Additionally, let your doctor or pharmacist know if you've recently stopped taking isotretinoin (Absorica, Amnesteem, Clavaris, and other brands). Inform your doctor and pharmacist about all other prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are currently taking or intend to take, and ask for a list of the ingredients from your pharmacist. Warfarin (Coumadin, Jantoven) and other anticoagulants (also known as "blood thinners") should be mentioned, as should any ergot-type drugs like bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine ( Before taking minocycline, let your doctor and pharmacist know if you have any allergies to it, to tetracycline, to doxycycline, to demeclocycline, to any other drugs, or to any of the ingredients in minocycline capsules, pellet-filled capsules, or extended-release tablets. Plan to avoid unnecessary or prolonged exposure to sunlight, and to wear protective clothing, sunglasses, and sunscreen. Do not drive a car or operate machinery until you know how this medication affects you. Please call your doctor right away if you find out you're pregnant while taking minocycline. Minocycline can harm the fetus. you should know that minocycline may make you lightheaded or dizzy. Minocycline decreases the effectiveness of some oral contraceptives; talk to your doctor about selecting another form of birth control to use while taking this medication. be aware that antacids containing magnesium, aluminum, or calcium, calcium supplements, zinc products, iron products, and laxatives containing magnesium interfere with minocycline, making it less effective. You should be aware that taking minocycline while pregnant, in young children up to the age of 8, or in infants can result in teeth that are permanently stained. Minocycline may also make your skin more sensitive to sunlight. Minocycline should not be administered to children under the age of 8 unless they have inhaled anthrax or if your doctor deems it necessary. Minocycline should be taken 2 hours before or 4 hours after iron preparations and iron-containing vitamins. Tell your doctor if you have or have ever had asthma, lupus (a condition in which the immune system attacks many tissues and organs including the skin, joints, blood, and kidneys), intracranial hypertension (pseudotumor cerebri; high pressure in the skull that may cause headaches, blurry or double vision, vision loss, and other symptoms), kidney, or liver disease. you should know that minocycline may decrease your ability to absorb zinc. Minocycline should be taken 2 hours before or 6 hours after taking antacids, calcium supplements, or laxatives that contain magnesium. Talk to your doctor about using another form of birth control. tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Your doctor might need to adjust the dosage of your medications or keep a close eye on you for side effects.
Adults and children 12 years of age and older (extended-release tablets): The recommended dose for minocycline is: Approximately 1 mg/kg by mouth once daily for up to 12 weeks for the treatment of inflammatory lesions of non-nodular acne vulgaris. Safe and effective use of minocycline is not established for children under the age of 8. Adults (immediate-release tablets and capsules): The recommended dose for minocycline is: 200 mg initially, followed by 100 mg every 12 hours.
The avai labi l i ty of gener ic formulat ions of minocycline has created confusion regarding the clinical signif icance of brand versus… In the United States, Propionibacterium acnes resistance is lowest with minocycline compared with other tetracyclines and with erythromycin. VOLUME 77, MARCH 2006 153 Minocycline is an oral antibiotic widely prescribed throughout the world, primarily for the treatment of acne vulgaris; other uses include the treatment of rosacea and perioral dermatitis.
Limitations of Use XIMINO did not demonstrate any effect on non-inflammatory acne lesions. Superinfection: XIMINO may result in overgrowth of nonsusceptible organisms, including fungi. Safety of XIMINO has not been established beyond 12 weeks of use. This formulation of minocycline has not been evaluated in the treatment of infections.
It is effective in reducing inflammation and killing acne-causing bacteria. Minocycline is a prescription oral antibiotic that treats inflammatory acne.
The long-term safety profile after 52 weeks of daily application was similar to that seen after the 12 weeks of use in the double-blind Phase 3 studies. This is good news for rosacea sufferers as very few Zilxi User Reviews are available online. Together, the positive efficacy outcomes, favorable 52-week safety profile, and patient satisfaction with FMX103 1.5% may foster patients’ adherence to therapy.
CAS number 13614-98-7 • Molecular weight CHNO.HCl = 493.9 • Assay > 96 % Minocycline is a bacteriostatic antibioticum with activity against gram-positive and gram-negative bacteria. Within the cell minocycline binds reversible to the 30S subunit of the ribosome, preventing the binding of aminoacyl transfer RNA and inhibiting protein synthesis and hence cell growth. Minocycline has a spectrum of activity the same as tetracycline but witha better microbial activity against many species.
Minocycline is contraindicated in children of less than 12 years of age. Cross-resistance between tetracyclines may develop in micro-organisms and cross-sensitisation in patients. Cross-hypersensitivity between tetracyclines may occur in patients (see section 4.3). If a photosensitivity reaction occurs (see section 4.8), patients should be warned to avoid direct exposure to natural or artificial light and to discontinue therapy at the first signs of skin discomfort.