Description
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release., The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. US Pharmaceutical Holdings I began developing metoprolol in 1969, and the FDA gave its approval in 1978. It continues to be one of the preferred beta-blockers in general clinical guidelines, and it is frequently prescribed in the US, New Zealand, and the Netherlands.
Dosage
Information about Metoprolol dosage in detail Initial dose: -Metoprolol tartrate immediate release tablets: 50 mg orally twice a day -Metoprolol succinate extended release tablets: 100 mg orally once a day Maintenance dose: 100 to 400 mg per day. Metoprolol Succinate Extended Release Tablets: Take 25 mg orally once daily (12.5 mg orally once daily in patients with more severe heart failure); double dose every 2 weeks to the highest tolerated dose or up to 200 mg orally once daily. Metoprolol Succinate Extended Release Tablets: 6 Years or Older: Initial dose: 1 mg/kg orally once a day (not to exceed 50 mg orally once a day) Maximum dose: 2 mg/kg (or 200 mg) orally once a day. Metoprolol Succinate Extended Release Tablets: Maintenance dose: 100 to 400 mg orally once daily; Initial dose: 25 to 100 mg orally once daily. Metoprolol Tartrate: Early Treatment: Initial dose: 5 mg intravenously every two minutes as tolerated for three doses -Patients tolerant of full IV dose (15 mg): 50 mg orally every six hours starting 15 minutes after the last IV dose and continued for 48 hours -Patients intolerant of full IV dose (15 mg): 25 or 50 mg orally every six hours depending on the degree of intolerance starting 15 minutes after the last IV dose or as soon as their clinical Initially, take 100 mg of metoprolol tartrate orally, either all at once or in two doses, per day. Afterward, take 100 to 450 mg orally, as needed. Usual Adult Dose for Angina Pectoris: For congestive heart failure, the typical adult dosage is: Usual Adult Dose for Hypertension: The typical adult dosage for myocardial infarction is: Standard pediatric dosage for hypertension
Missed dose
Never take two doses at once to make up for missed ones. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. As soon as you realize you missed a dose, take it.
Overdose
Get immediate medical help or dial 1-800-222-1222 for poison help.
Storage
This medication should not, however, be flushed down the toilet. A medicine take-back program is the preferable method for getting rid of your medication. All medications should be kept out of the sight and reach of children, as many containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for small children to open. Keep this medication tightly closed in its original container away from the reach of children. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. It should not be kept in the bathroom. Store it at room temperature, away from sources of extreme heat and moisture. To find out about take-back programs in your neighborhood, speak with your pharmacist or get in touch with your city's waste/recycling department. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
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Toprol XL (Metoprolol) works by blocking the action of certain natural chemicals in body (such as epinephrine ) that affect the heart and blood vessels. Postponing the visit to doctor in case of bad feeling is a risk for your life. Toprol XL (Metoprolol) is a beta-blocker used to treat chest pain ( angina ), heart failure , and high blood pressure . Almost always taking of Toprol XL (Metoprolol) goes without any side effects but at least there can be some cases: very slow heartbeat; shortness of breath; dizziness; tiredness; confusion; memory problems; nightmares, trouble sleeping; diarrhea; mild itching or rash. Before taking this medication consult with your attending physician.
Toprol XL (Metoprolol) works by blocking the action of certain natural chemicals in body (such as epinephrine ) that affect the heart and blood vessels. The standard initial dose is 25-50 mg / day. Toprol XL (Metoprolol) is taken orally in the morning, taken down with water.
If you stop taking metoprolol, it will take 1 to 2 days for it to be completely out of your body. If you do not feel dizzy after the first dose, take metoprolol in the morning. Taking too much metoprolol can slow down your heart rate and make it difficult to breathe. If you're bothered by any side effects, your doctor may be able to prescribe a different medicine for your heart problems. high blood pressure – 50mg to 100mg, taken twice a day chest pain – 50mg to 100mg, taken 2 to 3 times a day an irregular heartbeat – 50mg, taken 2 to 3 times a day preventing migraine – 50mg to 100mg, taken twice a day too much thyroid hormone (thyrotoxicosis) – 50mg, taken 4 times a day Some tablets have a score line to help you break them in half and make it easier to swallow.
So with long term Merool therapy, when discontinuing, if needed, it must be tapered off because with long term use, there tends to be receptor changes. This is an oral medication, as you can see here. Hey guys, let’s talk about Metoprolol also known as Topal XL or low pressure. Metoprolol is cardio selective, which means it does not usually affect beta two receptors. The therapeutic class of MEO is an antianginal and also an anti-hypertensive medication while the pharmacologic class or the chemical effect of the drug is a beta blocker.
It is important to note that Seniors may need a smaller dosage of metoprolol at first then continue to increase dosage slowly and gradually under the instruction of a doctor. This blog answered the question “Can metoprolol be used for anxiety?” The blog also briefly touched upon what Metoprolol is, it’s use, side effects, and precautions to be taken related to use. The study also suggested that it could be possible that beta-blockers could be a better form of treatment than Benzodiazepines because Benzodiazepines has a wide range of side effects, and puts some groups of individuals at a higher risk of addiction or dependency to the drug.
Headache, somnolence, nightmares, and insomnia have also been reported. Nausea, dry mouth, gastric pain, constipation, flatulence, digestive tract disorders, and heartburn have been reported in about 1 of 100 patients. Central Nervous System Tiredness and dizziness have occurred in about 10 of 100 patients. Mental confusion and short-term memory loss have been reported.
Atenolol vs Metoprolol – Which Is Better For Hypertension? The maintenance dosage is 50 to 100 mg orally once per day. The maintenance dosage is 100 to 450 mg per day. Side Effects And Precaution Of Lopressor nausea; stomach pain; dizziness; depression; a runny nose; tiredness; cold hands and feet; dry mouth; itching; constipation; heartburn; bloating; vomiting. Although these medicines have similar effects on blood pressure reduction, they have different effects on vascular function.