Shopping Cart: USD 0.00 (0 items) Shopping Cart
FREE
SHIPPING!

on all orders above $300.00

FREE Pills!

via4gra pills

for free with every order

OUR DRUG PRICES are

70%

Less than in your
local pharmacy

  Insurance Delivery   15 years Worldwide Supplier   100% Satisfaction Guarantee   High Quality Medications

Search by letter:

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Methotrexate
+ BONUS

Rating of sales:          

 
methotrexate injection sites

Antimetabolite of folic acid Use is contraindicated in patients with a nonmalignant diagnosis who are pregnant; due to the potential for serious or fatal adverse reactions, treatment with methotrexate requires an experienced physician Used for both malignant and nonmalignant conditions, including rheumatoid arthritis, juvenile idiopathic arthritis, psoriasis, breast cancer, non-Hodgkin lymphoma, and ALL. Intrathecal methotrexate is also used to prevent and treat meningeal leukemia.

Other names for this medication:
Metoject, Rasuvo, Reditrex, Xatmep, Trexall, Nordimet, Otrexup

Similar Products:
Leukeran, Cyclophosphamide, Letrozole, Xeloda, Hydroxyurea, Cytoxan, Ondansetron, Nolvadex, Zofran, Capecitabine, Femara, Chlorambucil, Hydrea

Description

Due to these side effects, methotrexate is frequently used to treat arthritic inflammation or to regulate cell division in neoplastic diseases like breast cancer and non-Hodgkin's lymphoma.,,,, Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients are intolerant of those treatments. A folate derivative called methotrexate blocks several nucleotide-synthesising enzymes. The FDA approved methotrexate on December 7, 1953. Due to this inhibition, cell division is stopped as well as inflammation.

Dosage

In a hospital or cancer treatment facility, methotrexate will be administered by a nurse or other qualified healthcare provider. The medical issue for which you are using the medication will also determine how many doses you take each day, how long you wait between doses, and how long you take it for. If you have any inquiries, speak to your doctor. Children—Your doctor must determine the dosage for you based on your child's body weight. Children—Your doctor must determine the use and dosage. Observe your doctor's orders or the instructions on the product's label. Adults—At first, 10 to 25 milligrams (mg) once per week for psoriasis in the form of an injection. Adults—7.5 mg once a week at first for rheumatoid arthritis or pediatric arthritis. The dose is typically no higher than 30 mg administered once weekly. Use caution if the medication in the syringe has changed color or has visible particles. If you inject Otrexup, Rasuvo, or Reditrex at home: If your dose is different, don't adjust it unless your doctor instructs you to do so. Make sure to rotate the body parts by keeping track of where you administer each shot. Shots of methotrexate can be administered subcutaneously, intravenously, intramuscularly, or into the spine (back or neck). Carefully read and adhere to the instructions. Depending on the medication's potency, you should take a different amount. For various patients, a different dose of methotrexate will be prescribed. The following information includes only the average doses of methotrexate. A patient information leaflet is included with the medication. Typically on the stomach or thigh, the medication is injected under your skin. The starting dose is 10 milligrams (mg) per square meter (m(2)) of body size once per week. This will lessen the chance of skin complications from the injection. Use a different body area each time you give yourself a shot. Your doctor may adjust your dose as needed.

Missed dose

If you forget to take your methotrexate dose, call your doctor for directions.

Overdose

Methotrexate taken in excess can be fatal. Overdose symptoms can include unusual bleeding, mouth sores, vomiting, little to no urination, bloody or tarry stools, or coughing up blood or vomit that resembles coffee grounds. Call the Poison Help hotline at 1-800-222-1222 or seek immediate medical attention.

Storage

Store at room temperature (15-25°C).

Keywords
  • antibiotics and methotrexate
  • apremilast vs methotrexate
  • arava vs methotrexate
  • augmentin methotrexate interaction
  • calcium folinate methotrexate
  • emc methotrexate injection
  • injectable methotrexate brands
  • injection de methotrexate
  • leflunomide vs methotrexate
  • liquid methotrexate
  • low dose methotrexate
  • methotrexate administration guidelines
  • methotrexate adverse effects
  • methotrexate amoxicillin interaction
  • methotrexate bnf children
  • methotrexate bnf dose
  • methotrexate bnf interactions
  • methotrexate bnf online
  • methotrexate booklet uk
  • methotrexate brand name
  • methotrexate contraindications
  • methotrexate cost
  • methotrexate dental implants
  • methotrexate dosage
  • methotrexate dosage calculator
  • methotrexate dosage chart
  • methotrexate dosage forms
  • methotrexate dose
  • methotrexate dose calculator
  • methotrexate drug class
  • methotrexate drug classification
  • methotrexate drug interaction
  • methotrexate drug interactions
  • methotrexate ectopic pregnancy
  • methotrexate for injection
  • methotrexate im injection
Side effects

If you experience any unusual issues while taking this medication, contact your doctor right away. You or your doctor can submit a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online at http://www.fda.gov/Safety/MedWatch or by phone at 1-800-332-1088 if you experience a serious side effect. Call your doctor right away if you experience any of the following symptoms or any of those mentioned in the IMPORTANT WARNING section: dizziness, drowsiness, headache, swollen, tender gums, decreased appetite, reddened eyes, hair loss, seizures, confusion, weakness, or difficulty moving one or both sides of the body, loss of consciousness. Methotrexate may also have other side effects. There may be side effects from methotrexate. If any of these side effects persist or are severe, consult your doctor right away: dizziness, drowsiness, headache, swollen, tender gums, decreased appetite, reddened eyes, hair loss, confusion, weakness, or difficulty moving one or both sides of the body, loss of consciousness.

Interactions

Ask your doctor or pharmacist for more information. Inform your doctor right away if you take any of the following medications: nonsteroidal anti-inflammatory drugs (NSAIDS), such as aspirin, choline magnesium trisalicylate (Tricosal, Trilisate), ibuprofen (Advil, Motrin), magnesium salicylate (Doan's), naproxen (Aleve, Naprosyn), or salsalate; acitretin (Soriatane), azathioprine ( Inform your doctor about all of the medications you take, including vitamins, herbal supplements, prescription and non-prescription drugs.

Contraindications

Elderly people, newborns, people with kidney or liver disease, and bone marrow depression. Monitor haematological, renal and hepatic function, and GI toxicity regularly. Ulcerative disorders of the GI tract.

How methotrexate works?

How Methotrexate Works to Help Fight Inflammation. Methotrexate is thought to work by causing cells to release a molecule that block chemicals that promote inflammation, according to the Arthritis Foundation. Reducing inflammation helps prevent pain and joint damage otherwise experienced by people with the disease.

Does methotrexate increase the risk of cervical cancer?

There is no evidence that methotrexate increases the risk of developing cervical cancer.

Is 25mg of methotrexate a lot?

The correct dose of methotrexate (commonly between 7.5mg to 25mg per week) will reduce inflammation and alleviate the condition it's prescribed for, whether that's rheumatoid arthritis, psoriasis, inflammatory bowel disease, and so on.

How long does it take to work?

Methotrexate can start working for rheumatoid arthritis within 3 to 6 weeks and symptoms continue to improve over 3 months. For other people it might take a few months before they notice any improvement in their rheumatoid arthritis symptoms.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide shipping

Worldwide shipping

Registered Mail  Not trackable 14-21 business days USD 20.00 per order
EMS  Trackable, where available 5-9 business days USD 30.00 per order

Delivery time is:

Registered Mail - 14-21 business days, prices - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, prices - USD 30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

front back side

This is exactly how your parcel will look like (pictures of a real shipping item). It has a look of a regular private letter and does not disclose its contents. Size - 9.4x4.3x0.3 inches (24x11x0.7cm).

Testimonials
Best
 Show Hide 
Jayden Hartley Oct 18, 2022, 10:20:38 PM

The cyclophosphamide dose was either a 500 mg/minjection every month or a 1-2 mg pill every day. This causes high levels of inflammation that lead to scar tissue building up in the skin. Sixty-five patients received 20 to 25 mg of methotrexate a week, while 118 received up to 1 g of CellCept (mycophenolate mofetil) twice a day, and 87 received cyclophosphamide. Another group of 56 patients did not receive any immunosuppressants for their scleroderma, although some were on steroid treatments.

jayiitb May 23, 2019, 2:10:06 PM

Mechanistically, histidine catabolism drains the cellular pool of tetrahydrofolate, which is particularly detrimental to methotrexate-treated cells. Although methotrexate is widely used as an anticancer agent and is the subject of over a thousand ongoing clinical trials, its high toxicity often leads to the premature termination of its use, which reduces its potential efficacy. The histidine degradation pathway markedly influences the sensitivity of cancer cells to methotrexate and may be exploited to improve methotrexate efficacy through a simple dietary intervention. This screen yielded FTCD, which encodes an enzyme—formimidoyltransferase cyclodeaminase—that is required for the catabolism of the amino acid histidine, a process that has not previously been linked to methotrexate sensitivity.

Ben Hummel Apr 15, 2010, 6:42:07 AM

These drugs are often used to treat similar conditions. This helps to treat the symptoms of psoriasis, which include dry, itchy patches of skin. Methotrexate self-injectable solution may be used as part of a combination therapy. It’s believed that methotrexate weakens your immune system, which may help reduce pain, swelling, and stiffness from RA. For psoriasis, methotrexate slows down how fast your body produces the top layer of your skin.

Rochelle Eskue Dec 26, 2012, 8:05:16 AM

Methotrexate continues to remain a highly effective drug in the treatment of cancer and autoimmune disorders. Clinical Pharmacology When we talk about the clinical pharmacology of methotrexate, we need to think about the following factors: Methotrexate must be taken once weekly. Methotrexate should be avoided in patients with hepatic dysfunction. Folinic acid is used to reverse the effects of methotrexate in overdose.

Rayyan Tomali Jun 30, 2022, 1:25:12 PM

This increases the risk of severe infections and other blood disorders. Typically, folic acid is given alongside methotrexate treatment – taken on a different day of the week (often recommended the day after methotrexate treatment). There are two primary modes of action with methotrexate: First, methotrexate inhibits dihydrofolate reductase (DHFR), an enzyme that plays a role in converting dihydrofolate to the active tetrahydrofolate (THF).

  Insurance Delivery   15 years WorldWide Supplier   100% Satisfaction Guarantee   High Quality Medications