A very serious allergic reaction to this drug is rare. There's a chance you'll feel sleepy, queasy, sick to your stomach, and dizzy. Get medical attention right away if any of these serious side effects manifest themselves: a severe headache, a fast, slow, irregular, or pounding heartbeat, chest pain, neck stiffness or soreness, severe nausea or vomiting, sweating or clammy skin (sometimes accompanied by fever), widened pupils, vision changes (such as double or blurred vision), or an abrupt sensitivity to light (photophobia). If you experience any of the following symptoms, seek medical attention right away: rapid heartbeat, hallucinations, loss of coordination, extreme dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness. However, seek immediate medical attention if you experience any serious allergic reaction symptoms, such as a rash, itching or swelling (especially of the face, tongue, or throat), extreme dizziness, or difficulty breathing. Inform your doctor or pharmacist right away if any of these side effects persist or get worse. Contact your doctor or pharmacist if you experience any additional effects not covered above. For medical guidance on side effects in Canada, contact your doctor. Call your doctor in the US for medical advice regarding side effects. This risk may be increased by a number of drug and food interactions (see the sections on how to use and drug interactions). The side effects of this medication are generally not severe in users. Keep in mind that your doctor has prescribed this medication because they believe it will benefit you more than it will harm you. Inform your doctor right away if you experience any severe side effects, such as: mental/mood changes (such as nervousness, irritability, confusion), signs of infection (such as sore throat that won't go away, fever), yellowing eyes/skin, unusual tiredness, or dark urine. Tell your doctor or pharmacist about all the medications you take (see the Drug Interactions section) because the risk increases if you also take other medications that raise serotonin. Rarely, this medication may result in a hypertensive crisis, a potentially fatal attack of extremely high blood pressure. The list of potential negative effects is not exhaustive. Serotonin syndrome/toxicity, a very serious condition, is a rare but severe side effect of this medication that may increase serotonin. You can contact the FDA to report side effects by calling 1-800-FDA-1088 or visiting www.fda.gov/medwatch. Health Canada can be contacted at 1-866-234-2345 if you wish to report side effects.
Additionally, let them know if you took fluoxetine within five weeks prior to starting metaxalone. Find out from your doctor how long you should wait before taking metaxalone after beginning or stopping any of these medications. Before beginning or stopping this medication, consult your doctor. Inquire with your pharmacist about the safe use of those products. The use of herbal products (such as ephedra/ma huang), nasal decongestants (such as phenylephrine, pseudoephedrine), and stimulants (such as amphetamines, ephedrine, epinephrine, phenylalanine) should be disclosed before taking metaxalone. These medications may increase the risk of extremely high blood pressure (hypertensive crisis) when combined with metax All of your medications, including those for allergies or colds and flu, should have their labels read carefully because they might contain drowsiness-inducing ingredients. Without your doctor's permission, you should never start, stop, or modify the dosage of any medications. Other MAO inhibitors, such as isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine, should not be taken while taking this medication. Drug interactions could alter how your medications function or raise the possibility of serious negative side effects. Examples include illegal substances like MDMA/"ecstasy," St. John's wort, some antidepressants, such as mirtazapine, SSRIs like fluoxetine/paroxetine, and SNRIs like duloxetine/venlafaxine, tramadol, and some "triptans" used to treat migraines, like rizatriptan, sumatriptan, and zolmitriptan, among others. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Make sure all of your doctors and the lab staff are aware that you use this medication. Any of these medicines shouldn't be taken with metroxalone. For two weeks prior to and following treatment with this medication, most MAO inhibitors should also be avoided. View the How to Use section as well. When taken concurrently, or even weeks before or after metaxalone administration, certain products may interact with one another. Diethylpropion, apraclonidine, bupropion, buspirone, carbamazepine, cyclobenzaprine, deutetrabenazine, a specific combination product (dextromethorphan/quinidine), levodopa, maprotiline, methyldopa, metoclopramide, certain opioid pain relievers (such as fentanyl, meperidine, methadone, tap This medication may interact negatively (and even fatally) with other MAO inhibitors when taken together. For more information, consult your doctor or pharmacist. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), other muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine). If you take anything on the list of products that could interact with this medication or any products that boost serotonin within 2 weeks of taking metaxalone, let your doctor or pharmacist know. If you also take other medications that raise serotonin, the risk of serotonin syndrome or toxicity rises. When you begin taking these medications or up the dose, the risk of serotonin syndrome/toxicity may increase. All possible drug interactions are not covered in this document. This medication may interfere with certain laboratory tests (including certain urine glucose tests), possibly causing false test results.
You might feel more groggy or faint if you drink alcohol or use marijuana (cannabis). Steer clear of alcohol. Inform your surgeon or dentist of everything you use, including prescription, over-the-counter, and herbal products. If you have any allergies, including to metaxalone or any other medications, let your doctor or pharmacist know before taking metaxalone. Inform your doctor or pharmacist about your medical history before taking this medication, particularly if it includes any history of liver disease, kidney disease, anemia, or seizures. Before breastfeeding, talk to your doctor. Describe the advantages and disadvantages to your doctor. Until you can do something safely, avoid operating machinery, driving, or doing anything else that requires alertness. Only use this medication during pregnancy if absolutely necessary. It is unknown if this drug passes into breast milk. Especially dizziness, drowsiness, or confusion, this medication's side effects may be more noticeable in older adults. If you use cannabis (marijuana), speak with your doctor. For more information, speak to your pharmacist. The risk of falling can rise as a result of these side effects. You might feel lightheaded or sleepy after taking this medication. Inactive ingredients in this product could result in allergic reactions or other issues.