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mellaril medication discontinued

Physician reviewed Mellaril patient information - includes Mellaril description, dosage and directions.

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Clozaril, Loxapine, Thorazine, Skelaxin, Thioridazine, Atomoxetine, Prochlorperazine, Buspar, Clozapine, Chlorpromazine, Loxitane, Anafranil, Compazine, Metaxalone


Mellaril should not be taken in two doses at once. Skip the missed dose and take your next dose at the scheduled time if it is almost time for your next dose. Take the missed dose right away if you forget to do so. Take Mellaril exactly as prescribed. Usually taken two to four times daily, with or without food, this medication comes in tablet form.


Information on the exact Mellaril dosage. Read all medication guides or instruction sheets and adhere to all directions on your prescription label. Inform the surgeon in advance that you are using Mellaril if you require surgery. Store at room temperature away from moisture, heat, and light. Follow the medication's instructions exactly. Regular medical exams are required. On occasion, your doctor might adjust your dosage. An electrocardiograph, also known as an ECG or EKG, may be used to examine your heart's functionality.

Missed dose

Taking two doses at once is not advised. If it is almost time for your next dose, skip the missed dose and take the medication as soon as you remember.


However, if overdose is thought to have occurred, get emergency medical help. It is unlikely that an overdose will happen if Mellaril is given by a healthcare professional in a hospital setting. If you take too much Mellaril, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

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Side effects

In the event that you experience: For medical guidance on side effects, call your doctor. The following are examples of frequent side effects: If you experience any of the following symptoms of an allergic reaction: hives, trouble breathing, swelling of your face, lips, tongue, or throat, seek emergency medical attention. Thioridazine use over an extended period of time or at high doses can result in serious movement disorders that may not be treatable. Effects of Mellaril (more information) The longer you use Mellaril, the more likely you are to develop this disorder, especially if you are a woman or an older adult. This is not a complete list of side effects and others may occur. Contact the FDA at 1-800-FDA-1088 to report side effects. Drowsiness, a dry mouth, blurred vision, nausea, vomiting, constipation, diarrhea, breast discharge, changes in your menstrual cycle, or swelling in your hands or feet are all signs that you may be taking birth control. uncontrolled muscle movements in your arms, legs, or face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); agitation, confusion; seizure (convulsions); decreased night vision, tunnel vision, watery eyes, increased sensitivity to light; little or no urinating; low white blood cell counts--fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing, feeling light-headed; or severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.


Inform your doctor of all the drugs you take, including vitamins, herbal supplements, prescription and non-prescription medications.


Do not drive or operate heavy machinery until you know how Mellaril affects you. If you have an allergy to Mellaril or any of its ingredients, are taking a medication that can cause Torsades des Pointes, quinidine (Qualaquin), fluoxetine (Prozac, Sarafem), amitriptyline (Elavil, Amitril), or paroxetine (Paxil), are taking a medication that significantly impairs alertness, are in a coma, have extremely high blood pressure, or have extremely low The mouth and lower portion of the face are typically affected. Drugs that act on the brain can have side effects that can lead to NMS, a condition that is potentially fatal. QT prolongation is one of the serious side effects of Mellaril that has been reported. Before beginning to take thioridazine, discuss the other medications you are currently taking with your healthcare provider. If you experience any of the following NMS signs or symptoms, contact your doctor right away: high fever, sweating, fluctuating blood pressure, confusion, rigid or stiff muscles, or a low white blood cell count. If you experience any of the following QT prolongation symptoms or signs, you should contact your doctor right away: feeling faint, lightheaded, dizzy, or having a rapid or irregular heartbeat (Tardive Dyskinesia). If you experience any of the following signs or symptoms of a low white blood cell count: frequent infections Fever Sore throat Severe chills Seizures Mellaril can make you feel sleepy. Tell your healthcare provider right away if you have any signs or symptoms of tardive dyskinesia: finger movements or twitching involuntary movements, or twitching of the mouth constantly sticking out the tongue, or tongue thrusting repetitive chewing swinging of the jaw Neuroleptic Malignant Syndrome (NMS). This illness results in the body twitching (moving against its will). This is a condition where your heart's electrical activity changes, leading to irregular heartbeats that could be fatal. Your white blood cells are responsible for protecting the body from infections.

Is Mellaril the same as Thorazine?

Thorazine, a brand name for chlorpromazine, and thioridazine, the generic name of Mellaril, represent such a pair. Chlorpromazine, brand name Thorazine, is a first-generation antipsychotic. It is a phenothiazine that blocks dopamine receptors in the post-synaptic membrane in the meso-limbic pathway.

What is Mellaril used for?

This medication is used to treat certain mental/mood disorders (such as schizophrenia). This medication helps you to think more clearly, feel less nervous, and take part in everyday life. It can also help prevent suicide in people likely to harm themselves and reduce aggression and the desire to hurt others.

What kind of drug is Mellaril?

Mellaril (thioridazine HCl) is an anti-psychotic medication in the phenothiazine class used to treat psychotic disorders such as schizophrenia, and is usually given after other medications have been tried without successful treatment of schizophrenia.

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Thioridazine, chlorpromazine, perphenazine, haloperidol, and risperidone have been noted to inhibit CYP2D6 and could increase the plasma concentration of metoclopramide. Pharmacokinetic interaction between fluoxetine and metoclopramide in healthy volunteers. Genetic variations in CYP2D6 or P-gp may alter the risk of movement disorders in patients taking metoclopramide. Concurrent administration of metoclopramide with CYP2D6 inhibitors (eg, amiodarone [Cordarone], diphenhydramine [Benadryl], propafenone [Rythmol], quinidine, ritonavir [Norvir], terbinafine [Lamisil], dronedarone [Multaq], bupropion [Wellbutrin]) or P-gp inhibitors (eg, clarithromycin [Biaxin], cyclosporine [Neoral], verapamil [Calan], ketoconazole [Nizoral], tacrolimus [Prograf], itraconazole [Sporanox], nelfinavir [Viracept]) should probably be avoided pending further data.

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