A very serious allergic reaction to this drug is rare. Furthermore, thrombotic thrombocytopenic purpura, or TTP, is a very serious blood disorder that can be very rarely brought on by clopidogrel. Although unlikely, serious bleeding in the stomach, gut, eyes, or brain may occur. Constipation, diarrhea, easy bruising/bleeding, and stomach discomfort/pain may also appear. Get medical help right away if any of these symptoms occur: severe stomach/abdominal pain, uncontrolled bleeding from gums or nose, bloody/black stools, confusion, fever, extreme skin paleness, purple skin patches, fainting, fast heartbeat, sudden severe headache, unusual weakness/tiredness, vomit with blood or that looks like coffee grounds, trouble speaking, vision changes, seizures, yellowing eyes/skin, bloody/red/pink/dark urine, signs of kidney problems (such as change in the amount of urine). However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Inform your doctor or pharmacist right away if any of these side effects last longer or get worse. Contact your doctor or pharmacist if you experience any additional effects that aren't covered above. For medical advice about side effects in Canada, contact your doctor. Call your doctor for medical advice about side effects if you're in the US. Several users report no significant side effects from this medication. Keep in mind that your doctor has prescribed this medicine because they believe it will benefit you more than it will harm you. Symptoms may appear any time after starting this medication. The list of potential side effects presented here is not exhaustive. You can contact the FDA to report side effects at 1-800-FDA-1088 or online at www.fda.gov/medwatch. Call 1-866-234-2345 to report side effects to Health Canada.
Drug interactions with clopidogrel (more information) Not all possible drug interactions are listed here. Prescription, over-the-counter, and herbal medications, as well as vitamins, may all have an impact on clopidogrel. Some medications can change the levels of other medications you take in your blood, which could increase side effects or reduce the effectiveness of the medication. Utilizing certain medications concurrently is occasionally not advised. Tell your doctor about all of your current medications, in particular: This isn't a comprehensive list. rifampin; a blood thinner like warfarin, Coumadin, or Jantoven; a stomach acid-reducing medication like omeprazole, Nexium, or Prilosec; an antidepressant like citalopram, fluoxetine, sertraline, Cymbalta, Effexor, Lexapro, Pristiq, or Prozac; or NSAIDs (nonsteroidal anti-inflammatory drugs) like aspirin, ibupro
Inform your doctor and pharmacist about all other prescription and non-prescription drugs, vitamins, dietary supplements, and herbal products you are taking or intend to take, and be sure to get a list of the ingredients by asking your pharmacist or looking it up in the Medication Guide. If you have an allergy to clopidogrel, prasugrel (Effient), ticlopidine, any other medications, any ingredient in clopidogrel tablets, or any other substance, let your doctor and pharmacist know before you start taking clopidogrel.