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Clopidogrel
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dipyridamole vs clopidogrel

Patients who have experienced a heart attack or stroke are protected from blood clot formation by clopidogrel. Any unusual bleeding should be reported to your doctor.

Other names for this medication:
Plavix, Zyllt, Duoplavin

Similar Products:
Lanoxin, Ramipril, Altace, Coumadin

Description

For more information, speak with your doctor or pharmacist. A prescription drug called clopidogrel is given to people who have recently been admitted to the hospital for chest pains, a heart attack, or a stroke to keep their blood vessels from clotting. It is also used in people with certain heart and blood vessel disorders. Other prescriptions for this medicine might be given.

Dosage

Clopidogrel should be taken once daily, with or without food, in doses of 75 mg.

Missed dose

To catch up, do not double the dose. Skip the missed dose if it is almost time for the next dose. As soon as you remember, take the missed dose. Take your next dose at the regular time.

Overdose

A provincial poison control center is accessible to Canadian citizens. For further information, talk to your doctor. Consult your pharmacist or the neighborhood waste management company. Do not double the dose to catch up. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Don't give anyone else this medication. Do not keep items in the bathroom. Skip the missed dose if the time for the subsequent dose is approaching. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Take the missed dose as soon as you remember it if you miss it. Pets and children should not have access to any medications. Periodically, laboratory and/or medical tests (like a complete blood count) may be carried out to track your development or look for side effects. In any other case, immediately dial a poison control number. When the product has run its course or is no longer required, dispose of it properly. Store at room temperature away from light and moisture. Take your next dose at the regular time. The local poison control center can be reached by calling 1-800-222-1222 for US citizens.

Storage

Consult your pharmacist or the neighborhood waste management company. Unless specifically instructed to do so, avoid flushing or pouring medications down the drain. Do not store in the bathroom. Keep children and pets away from all medications. When the product has run its course or is no longer required, properly dispose of it. Away from light and moisture, keep items at room temperature.

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Side effects

A very serious allergic reaction to this drug is rare. Furthermore, thrombotic thrombocytopenic purpura, or TTP, is a very serious blood disorder that can be very rarely brought on by clopidogrel. Although unlikely, serious bleeding in the stomach, gut, eyes, or brain may occur. Constipation, diarrhea, easy bruising/bleeding, and stomach discomfort/pain may also appear. Get medical help right away if any of these symptoms occur: severe stomach/abdominal pain, uncontrolled bleeding from gums or nose, bloody/black stools, confusion, fever, extreme skin paleness, purple skin patches, fainting, fast heartbeat, sudden severe headache, unusual weakness/tiredness, vomit with blood or that looks like coffee grounds, trouble speaking, vision changes, seizures, yellowing eyes/skin, bloody/red/pink/dark urine, signs of kidney problems (such as change in the amount of urine). However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Inform your doctor or pharmacist right away if any of these side effects last longer or get worse. Contact your doctor or pharmacist if you experience any additional effects that aren't covered above. For medical advice about side effects in Canada, contact your doctor. Call your doctor for medical advice about side effects if you're in the US. Several users report no significant side effects from this medication. Keep in mind that your doctor has prescribed this medicine because they believe it will benefit you more than it will harm you. Symptoms may appear any time after starting this medication. The list of potential side effects presented here is not exhaustive. You can contact the FDA to report side effects at 1-800-FDA-1088 or online at www.fda.gov/medwatch. Call 1-866-234-2345 to report side effects to Health Canada.

Interactions

Drug interactions with clopidogrel (more information) Not all possible drug interactions are listed here. Prescription, over-the-counter, and herbal medications, as well as vitamins, may all have an impact on clopidogrel. Some medications can change the levels of other medications you take in your blood, which could increase side effects or reduce the effectiveness of the medication. Utilizing certain medications concurrently is occasionally not advised. Tell your doctor about all of your current medications, in particular: This isn't a comprehensive list. rifampin; a blood thinner like warfarin, Coumadin, or Jantoven; a stomach acid-reducing medication like omeprazole, Nexium, or Prilosec; an antidepressant like citalopram, fluoxetine, sertraline, Cymbalta, Effexor, Lexapro, Pristiq, or Prozac; or NSAIDs (nonsteroidal anti-inflammatory drugs) like aspirin, ibupro

Contraindications

Inform your doctor and pharmacist about all other prescription and non-prescription drugs, vitamins, dietary supplements, and herbal products you are taking or intend to take, and be sure to get a list of the ingredients by asking your pharmacist or looking it up in the Medication Guide. If you have an allergy to clopidogrel, prasugrel (Effient), ticlopidine, any other medications, any ingredient in clopidogrel tablets, or any other substance, let your doctor and pharmacist know before you start taking clopidogrel.

When will I feel better?

You may not feel any different after you start taking clopidogrel. However, this does not mean that the medicine is not working. Carry on taking clopidogrel even if you feel well, as you'll still be getting the benefits.

Is clopidogrel bisulfate a blood thinner?

Plavix (clopidogrel bisulfate) and Coumadin (warfarin) are anticoagulants (blood thinners) used to treat patients with acute coronary syndrome, heart attack (myocardial infarction), peripheral vascular disease, and ischemic strokes.

What is the difference between aspirin and clopidogrel?

What is the difference between aspirin and Plavix (clopidogrel)? Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID).

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Testimonials
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Garnetta Jackson Sep 9, 2022, 11:56:38 PM

And there are some food and interactions that increase the risk of bleeding, things like garlic, Ginko, and ginger. Finally, you must teach your patient they have to discontinue Clopidogrel five to seven days before surgery. And as a result, their surgery is most definitely canceled. Well, it works by inhibiting platelet aggregation, and we use Clopidogrel for atherosclerotic events, MI myocardial infarction, CVA, peripheral vascular disease, and acute coronary syndrome.

Radu Stefan Oct 10, 2011, 11:35:33 AM

Methods and Results: We conducted a population-based observational study to determine whether generic clopidogrel was noninferior to Plavix. Our study included 24 530 patients with ACS, 12 643 were prescribed Plavix and 11  887 were prescribed generic clopidogrel at hospital discharge. After patent protection expired for Plavix in 2012, many healthcare systems adopted generic clopidogrel as a strategy to reduce healthcare costs.

user1279887 Jan 20, 2017, 9:28:18 PM

Thời gian bán thải của dạng chuyển hoá chính (không có hoạt tính) là 8 giờ khi sử dụng liều đơn và liều nhắc lại. Do dạng chuyển hoá có hoạt tính của clopidogrel được tạo ra nhờ xúc tác của enzym CYP450 nên một số bệnh nhân mang đa hình di truyền hoặc có hệ CYP450 bị ức chế bởi các thuốc khác có thể không đạt được tác dụng ức chế tiểu cầu thỏa đáng. Hội chứng mạch vành cấp không có đoạn ST chênh lên (đau thắt ngực không ổn định hoặc nhồi máu cơ tim không có sóng Q), kể cả những bệnh nhân đang được đặt stent sau khi can thiệp mạch vành qua da, sử dụng phối hợp với acid acetylsalicylic (ASA).

Joeran Preller Mar 17, 2012, 8:12:46 AM

• Heparin: Tương tác dược lực học giữa Clopidogrel và Heparin có thể dẫn đến tăng nguy cơ xuất huyết. Cho nên nó có thể ảnh hưởng đến quá trình chuyển hóa của phenytoin, tamoxifen, tolbutamid, warfarin, torsemid, fluvastatin và nhiều chất kháng viêm không steroid khác, nhưng không có dữ liệu về mức nghiêm trọng của các tương tác trên. Tuy nhiên, Clopidogrel và Aspirin có thể được phối hợp trong thời gian kéo dài đến 1 năm.

leakey Feb 9, 2010, 4:39:10 PM

The recalled product ― lot number 117099A of clopidogrel tablets (USP 75 mg) packaged in bottles of 30 tablets ― may contain clopidogrel 75 mg tablets or it could contain simvastatin tablets (USP 10 mg), according to a company announcement posted on the US Food and Drug Administration (FDA) website. Follow Medscape on Facebook, Twitter, Instagram, and YouTube. For questions regarding this recall, contact Inmar by phone 855-258-7280 (weekdays between 9:00 AM and 5:00 PM EST) or by email at [email protected] Additionally, unintentional consumption of simvastatin could include the common side effects associated with its use and may cause fetal harm when administered to a pregnant woman," the company cautions. International Laboratories is notifying distributors and customers by letter and is arranging for the return of all recalled products.

JJ Medina Jul 12, 2015, 7:40:17 PM

Avoid driving or operating heavy machinery while taking this drug, because it may lead o dizziness Patients suffering from any bleeding disorder or peptic ulcer disease this medicine is not recommended. RosoGenic CV 10/75 – Rosuvastatin 10mg, Clopidogrel 75mg capsules for oral use. Patients should avoid consuming alcohol during treatment with this drug, because of increased risk of hepatic problems. Irritability Headache Nausea and Vomiting Stuffy nose Shortens breath Stomach pain Dyspepsia Hepatic problems Muscle pain Diarrhea Weakness Pregnant and lactating women should avoid the drug and consult physician before taking it.

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