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Levofloxacin
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levofloxacin uses

Linked to incapacitating and possibly irreversible adverse reactions, such as tendonitis, tendon rupture, peripheral neuropathy, and effects on the central nervous system quinolone antibiotics administered intravenously, topically, and orally used to treat bacterial conjunctivitis, sinusitis, chronic bronchitis, pneumonia, infections of the skin and skin structures, urinary tract infections, prostatitis, inhalation anthrax, and plague

Other names for this medication:
Quinsair, Levaquin

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Description

Local antibiograms should be consulted to ensure sufficient coverage of pertinent pathogens prior to use because antimicrobial susceptibility patterns vary geographically. In comparison to other antibiotics, it has an action that lasts for a relatively long time, allowing once or twice daily dosing. Levofloxacin has demonstrated in vitro activity against a number of aerobic gram-positive and gram-negative bacteria and may carry some activity against certain species of anaerobic bacteria and other pathogens such as Chlamydia and Legionella. Levofloxacin should only be used with caution in patients who have additional QTc-interval prolongation risk factors (such as hypokalemia or concurrent medications). This is because levofloxacin is linked to QTc-interval prolongation. Levofloxacin is bactericidal and inhibits bacterial DNA replication to produce its antimicrobial effects. Cross-resistance between levofloxacin and other fluoroquinolones may occur, but is unlikely to develop between levofloxacin and other antibiotic classes (e.g. macrolides) due to significant differences in chemical structure and mechanism of action. Resistance to levofloxacin may develop and is typically caused by mutations in DNA gyrase or topoisomerase IV, or via alterations to drug efflux.

Dosage

Information on the dosage of Levofloxacin in detail Levofloxacin should not be given to a third party. While taking levofloxacin, increase your fluid intake to keep your kidneys functioning normally. Read all medication guides or instructions before using any of the products listed on your prescription label. When not in use, keep the bottle securely closed. Levofloxacin will not treat a viral infection such as the flu or a common cold. Carefully measure liquid medications. Your risk of developing an infection that is drug-resistant rises if you miss doses. Store at room temperature away from moisture and heat. At least one hour before or two hours after a meal, take levofloxacin oral solution (liquid) on an empty stomach. Levofloxacin should be taken every day at the same time with water. Inform the lab staff that you use levofloxacin. You might receive inaccurate results from a urine drug test if this medication is used. Use a medicine dose measuring device (not a kitchen spoon) or the dosing syringe that is provided. Use the medicine exactly as directed. Even if your symptoms disappear quickly, take this medication for the entire recommended period of time. You may take levofloxacin tablets with or without food.

Missed dose

To make up for a missed dose, do not take a second one. To continue with your regular dosing schedule, skip the missed dose if it is almost time for the next one. If you miss a dose, take it as soon as you remember.

Overdose

Get immediate medical help or dial 1-800-222-1222 for poison help.

Storage

This medication should not, however, be flushed down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. All medications should be kept out of the sight and reach of children, as many containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for toddlers to open. Keep this medication tightly closed in its original container away from the reach of children. If you do not have access to a take-back program, visit the FDA's Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for more information. Keep it at room temperature and out of the bathroom and other places with excessive heat and moisture. To find out about take-back programs in your neighborhood, speak with your pharmacist or get in touch with your city's waste/recycling department. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.

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Side effects

For medical advice about side effects, contact your doctor. Typical negative effects may include: Get emergency medical help if you have severe and constant pain in your chest, stomach, or back. Get immediate medical attention if you experience symptoms of an allergic reaction (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, or a red or purple skin rash that spreads and results in blistering and peeling). Your aorta, the body's main blood vessel, may in rare circumstances become damaged as a result of levofloxacin use. Levofloxacin may have harmful side effects that require medical attention, such as tendon problems, nerve problems that could result in permanent nerve damage, severe mood or behavioral changes that occur even after just one dose, and low blood sugar that can result in a coma. Effects of levofloxacin (more information) If you experience: If you experience any of the following: The result could be fatal bleeding or serious injury. There may be other side effects; this is not a comprehensive list. You may report side effects to FDA at 1-800-FDA-1088. Low blood sugar symptoms include headache, hunger, sweating, irritability, dizziness, nausea, or feeling jittery or woozy; nerve symptoms include numbness, weakness, tingling, or burning pain in your hands, arms, legs, or feet; serious mood or behavior changes include nervousness, confusion, agitation, paranoia, hallucinations, memory issues, difficulty concentrating, or suicidal thoughts; or tendon rupture symptoms include sudden pain, swelling, bru headache, dizziness, nausea, constipation, or difficulty sleeping. the first sign of any skin rash, no matter how mild; muscle weakness; breathing issues; seizures; increased pressure inside the skull--severe headaches, ringing in the ears, nausea, vision issues, pain behind the eyes; or liver problems--upper stomach pain, loss of appetite.

Interactions

Kinetics are slightly changed by food, but not significantly enough to have clinical effects. Take with or without food.

Contraindications

Marijuana (cannabis) and alcohol both increase your feeling of vertigo. Be on the lookout for low blood sugar symptoms like trembling, shakiness, hunger, blurred vision, dizziness, or tingling in the hands or feet. Avoid tanning booths and sunlamps. Inform your surgeon or dentist of everything you use, including prescription, over-the-counter, and herbal products. Tell your doctor or pharmacist if you have any allergies before taking levofloxacin, as well as any other quinolone antibiotics (such as ciprofloxacin, moxifloxacin, or ofloxacin). Tell your doctor or pharmacist before using levofloxacin if you are taking any other medications, have any of the following medical conditions, or have had a family history of any of these conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), or slow heartbeat, QT prolongation, or sudden cardiac death. Before taking this medication, consult your doctor or pharmacist about your medical history, especially of: diabetes, joint/tendon issues (such as tendonitis, bursitis), kidney issues, mental/mood disorders (such as depression), a specific muscle condition (myasthenia gravis), nerve issues (such as peripheral neuropathy), seizure disorder, blood vessel issues (such as aneurysm or blockage of the aorta or other blood vessels, hardening of the As directed, check your blood sugar frequently, and inform your doctor of the results. Children may be at greater risk for joint/tendon problems while using this drug. Before breastfeeding, consult a doctor. With your doctor, go over the advantages and risks. With your doctor, go over the advantages and disadvantages. Until you can do something safely, avoid driving, operating machinery, and performing other tasks that call for alertness. This medication should only be taken during pregnancy if absolutely necessary. If you don't have access to these safe sources of glucose, quickly raise your blood sugar levels by consuming fruit juice or regular soda, or by eating a quick source of sugar like candy, honey, or table sugar. It is a good habit to always have glucose gel or tablets on hand to treat low blood sugar. The heart rhythm disorder QT prolongation may be brought on by levofloxacin. Typhoid vaccine and other live bacterial vaccines may not function properly when taken with levofloxacin. Particularly if you have diabetes, levofloxacin may infrequently result in serious changes in blood sugar. Limit alcoholic beverages. Keep sun exposure to a minimum. Your risk of QT prolongation could also be impacted by low blood potassium or magnesium levels. The risk of tendon issues, QT prolongation, and a sudden tear or break in the main blood vessel (aorta) may be higher in older adults, especially if they are also taking corticosteroids like prednisone or hydrocortisone. Rarely, QT prolongation can result in fast/irregular heartbeat that is serious (rarely fatal) and other symptoms like severe dizziness and fainting that require immediate medical attention. Ask your doctor for advice on how to use levofloxacin safely. If you use marijuana (cannabis), speak with your doctor. For more information, speak to your pharmacist. Inform your doctor of the reaction as soon as possible. If you experience skin blisters or redness, or if you get a sunburn, contact your doctor right away. Before receiving any vaccinations or immunizations, inform your healthcare provider that you are using levofloxacin. If you take other medications or have certain medical conditions that can lead to QT prolongation, your risk of experiencing it may increase. You might feel faint or woozy after taking this medication. This medication enters breast milk. You might become more sun-sensitive as a result of this medication. This product might include inactive components that could lead to allergic reactions or other issues. This risk could rise if you take specific medications (like diuretics or "water pills") or experience certain health issues, like excessive sweating, diarrhea, or vomiting. Eat meals regularly and don't skip them to help prevent low blood sugar. When outdoors, wear protective clothing and sunscreen. Keep an eye out for signs of high blood sugar, such as increased thirst and urination. In the event that a reaction occurs, your doctor might need to change your antibiotic or modify your diabetes medication.

What is the drug levofloxacin used for?

Levofloxacin is used to treat bacterial infections in many different parts of the body. It is also used to treat anthrax infection after inhalational exposure. Levofloxacin is also used to treat and prevent plague (including pneumonic and septicemic plague).

What is levofloxacin hemihydrate?

Description. Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.

What is levofloxacin infusion used for?

Levofloxacin injection is used to treat bacterial infections in many different parts of the body. It is also used to prevent an anthrax infection after inhalational exposure. This medicine is also used to treat and prevent plague (including pneumonic and septicemic plague).

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Testimonials
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Oleh Berehovskyi Aug 27, 2018, 2:52:02 PM

Chinese Guideline recommends quinolones as monotherapy or combined therapy drug, and emphasizes the use of quinolones with anti-P. aeruginosa effect (only levofloxacin and ciprofloxacin), but does not recommend aminoglycosides for monotherapy. In addition, levofloxacin has a favorable anti-Pseudomonas effect. With a resistance rate of 19%, levofloxacin is a preferred drug for P. aeruginosa .

Peter Molnar Jun 22, 2016, 4:39:13 AM

Fluoroquinolones worsen low blood glucose levels when combined with sulfonylureas (for example, glyburide [Micronase, Diabeta, Glynase, Prestab]). Difficulty sleeping Dizziness Abdominal pain Rash Abdominal gas Itching Possible serious side effects of levofloxacin include: Peripheral neuropathy Central nervous system effects Hypoglycemia Hyperglycemia Clostridium difficile-associated diarrhea Abnormal heart beats Liver dysfunction Sun sensitivity Other serious side effects and adverse events of levofloxacin include: Levofloxacin should be used with caution in patients with central nervous system diseases such as seizures, because rare seizures have been reported in patients receiving Levaquin. Many antibiotics, including levofloxacin, can alter the normal bacteria in the colon and encourage overgrowth of a bacterium responsible for the development of inflammation of the colon, (C. difficile or pseudomembranous colitis). Many antibiotics, including ofloxacin, can alter the normal bacteria in the colon and encourage overgrowth of a bacterium responsible for the development of inflammation of the colon (Clostridium difficile, pseudomembranous colitis). Pseudomembranous colitis can cause fever, abdominal pain, diarrhea, and sometimes even shock.

Corey Gouker Sep 24, 2017, 5:28:26 PM

Either the medication should be taken with food or without food also but it should be taken at a fixed time. For viral infections including the common cold, flu this medication is not beneficial as this antibiotic treats only bacterial infections. Even if you are feeling better then also the medication should be taken as long as the doctor has prescribed you so that the bacteria are killed and doesn’t persist again. This medication should be used under the guidance of doctors or Pharmacists.

Shao Line Dragons Dec 22, 2018, 5:15:30 AM

Levofloxacin Tablets belongs to a class of medicine also known as quinolone antibiotics which works by preventing the growth of bacteria as this medicine only treat infection related to bacterial problems. The company has established itself as the quality-oriented manufacturing firm producing GMP-DCGI & WHO approved products for PCD Pharma Franchise & third party manufacturing in India. The mild symptoms that may be there can be; CONTACT FOR LEVOFLOXACIN TABLETS MANUFACTURING AND SUPPLY Lifepure Labs is a famous Manufacturers & Trader of Levofloxacin Tablets in India. We have well-qualified workers who are working with us constantly.

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