Call your doctor if you have any unusual problems while taking this medication. You or your doctor can report a serious side effect to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online at http://www.fda.gov/Safety/MedWatch or by phone at 1-800-332-1088. Call your doctor right away if you experience any of the following symptoms, or seek emergency medical attention: hot flushes, night sweats, nausea, vomiting, loss of appetite, constipation, diarrhea, changes in weight, muscle, joint, or bone pain, excessive fatigue, headache, dizziness, weakness, swelling of the hands, feet, ankles, or lower legs, difficulty falling asleep or staying asleep, vaginal bleeding or irritation, breast pain, hair loss, blurry vision, chest pain. It can decrease the density of your bones and increase the chance of broken bones and fractures. Other adverse effects of letrozole could exist. There could be negative effects from letrozole. Discuss the dangers of using this medication with your doctor. The following symptoms should be reported to your doctor if they are severe or persistent: hot flushes, night sweats, nausea, vomiting, loss of appetite, constipation, diarrhea, changes in weight, muscle, joint, or bone pain, excessive fatigue, headache, dizziness, weakness, swelling of the hands, feet, ankles, or lower legs, difficulty falling or staying asleep, vaginal bleeding or irritation, breast pain, hair loss, chest pain, rash, hives, itching difficulty falling or staying asleep
For more information, consult your physician or pharmacist. If you use hormonal contraceptives (birth control pills, implants, patches, rings, and/or injections), hormone replacement therapy (HRT), or medications like raloxifene (Evista) or tamoxifen (Nolvadex), be sure to let your doctor know. This is not a comprehensive list of letrozole drug interactions. Inform your doctor about all of the medications you take, including vitamins, herbal supplements, prescription and non-prescription drugs.
As soon as you are taking letrozole, avoid operating heavy machinery or driving. If any of the following apply to you: you have not reached menopause; you are allergic to any letrozole ingredient. Osteoporosis may result from taking letrozole or other drugs that reduce the body's estrogen levels. A dose reduction may be necessary for patients with cirrhosis or severe liver disease who also have high blood cholesterol. Letrozole has been linked to serious side effects, such as decreased bone mineral density. if you are a woman over 55 or already have osteoporosis, talk to your doctor about this. elevated blood levels of letrozole in patients with liver disease. This medication is not intended for women who have not gone through menopause are pregnant Letrozole may also cause dizziness and/or blurred vision. Your blood cholesterol levels may be checked by your doctor, and you might need to take cholesterol-lowering medication.