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kaletra drug

Take Kaletra as directed every time. Unless your doctor advises you otherwise, do not stop taking Kaletra. With Kaletra, HIV infection is treated.

Other names for this medication:
Ritonavir, Norvir, Viekira Pak

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Description

A group of medications known as HIV protease inhibitors includes both lopinavir and ritonavir. For additional information, speak with your physician or pharmacist. Do not share personal items (such as needles/syringes, toothbrushes, and razors) that may have contacted blood or other body fluids. HIV levels should be lowered to improve the efficiency of your immune system. Ritonavir increases ("boosts") the levels of lopinavir. Two drugs—lopinavir and ritonavir—are included in this combination product. This helps lopinavir work better.Lopinavir/ritonavir is not a cure for HIV infection. This enhances your quality of life and decreases your risk of developing HIV complications, such as new infections or cancer. Together with other HIV medications, this product aids in the management of HIV infection. Continue taking all HIV medications as directed by your doctor to reduce your risk of passing the disease to others. Use an effective barrier method (latex or polyurethane condoms/dental dams) during sexual activity as directed by your doctor.

Dosage

Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Never chew, break, or crush the tablets. Do not skip any doses. If not instructed to do so by your doctor, do not take more or less of this medication than prescribed, stop taking it (or other HIV medications), even for a brief period of time. Doing so may cause the amount of virus to increase, make the infection more difficult to treat (resistant), or worsen side effects. For children, the dosage is also based on age, weight, and height. This medication should be taken at regular intervals for the best results. Didanosine can be taken concurrently with this medication if you are doing so, but you must take both of them without food. If you have any questions, ask your doctor or pharmacist. It is crucial to keep taking this medication—as well as other HIV medications—exactly as directed by your doctor. Children under the age of 18 should not take this medication once daily. Before beginning to take lopinavir/ritonavir and each time you receive a refill, read the Medication Guide and, if available, the Patient Information Leaflet that was given to you by your pharmacist. Completely swallow the tablets. Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. The dosage is determined by your health, how you respond to treatment, and any additional medications you might be taking. Take this medication at the same time(s) every day to aid in memory.

Missed dose

Do not take extra medicine to make up the missed dose. If your next scheduled dose is approaching, skip the missed dose. As soon as you remember, take the missed dose.

Overdose

Avoid keeping this product outside of the container for more than two weeks, especially in humid environments. A provincial poison control center is accessible to Canadian citizens. For further information, talk to your doctor. Consult your pharmacist or the neighborhood waste management business. To catch up, do not double the dose. Unless otherwise instructed, avoid flushing or pouring medications down the drain. Do not share this medication with others. Do not store in the bathroom. Do not switch types of this medication without instructions on how to do so by your doctor. Skip the missed dose if it is almost time for the subsequent dose. Call 911 if someone has overdosed and is exhibiting serious symptoms like fainting or difficulty breathing. If you miss a dose, take it as soon as you remember. Keep all medical and laboratory appointments. Keep children and pets away from all medications. Laboratory and/or medical tests (such as liver function, blood count, blood cholesterol/triglyceride levels, blood sugar) should be performed periodically to monitor your progress or check for side effects. Tablets, capsules, and an oral solution are all forms in which lopinavir/ritonavir is sold. Otherwise, make an immediate call to a poison control center. When the product has run its course or is no longer required, dispose of it properly. Away from light and moisture, keep the product in its original container at room temperature. Numbness or tingling in the arms, hands, legs, or feet are examples of overdose symptoms, as well as a change in the amount of urine. When the time comes, take your next dose. The local poison control center can be reached by calling 1-800-222-1222 for US citizens.

Storage

In humid environments, especially, don't keep this product outside of the container for more than two weeks. Speak with your pharmacy or the neighborhood waste removal service. Unless specifically instructed to do so, never flush or pour medications down the drain. Keep out of the bathroom. Away from children and pets, keep all medications. When the product has run its course or is no longer required, dispose of it properly. Store in the original container at room temperature away from light and moisture.

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Side effects

Rarely does this medication cause an extremely severe allergic reaction. As your immune system gets stronger, it can begin to fight off infections you already had, possibly causing disease symptoms to come back. While you are taking this medication, changes in body fat may occur (for example, more fat in the upper back and stomach regions, less fat in the arms and legs). Testing for cholesterol and triglycerides should be done beforehand and occasionally while taking this medication. To learn more, speak with your physician or pharmacist. There may be gastrointestinal upset, nausea, vomiting, headaches, diarrhoea, gas, and sleep disturbances. Discuss the risks and benefits of treatment with your doctor, as well as the possible use of exercise to reduce this side effect. Seek immediate medical attention if you experience any severe symptoms, such as unexplained weight loss, extreme fatigue, muscle or joint pain, severe or persistent headaches, numbness or tingling in the hands, feet, arms, or legs, changes in vision, signs of infection (such as fever, chills, swollen lymph nodes, difficulty breathing, cough, or non-healing skin sores), or symptoms of an overactive thyroid (such as irritability, nervousness, If you experience any extremely serious side effects, such as signs of a heart attack (such as pain in the left arm, jaw, or chest), severe dizziness, fainting, or a slow, fast, or irregular heartbeat, seek immediate medical attention. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Inform your doctor or pharmacist right away if any of these effects persist or get worse. Contact your doctor or pharmacist if you experience any additional side effects not covered above. For medical advice about side effects in Canada, contact your doctor. For medical advice about side effects in the US, call your doctor. The side effects of this medication are generally not severe in users. You should keep in mind that your doctor prescribed this medication because she or he thought it would benefit you more than it would harm you. If you experience any severe side effects, such as persistent nausea or vomiting, increased thirst or urination, confusion, stomach or abdominal pain, yellowing of the skin or eyes, or dark urine, call your doctor right away. These changes have an unknown origin and potential long-term consequences. Possible side effects are not covered in this list in full. This medication may cause an increase in blood fat levels (cholesterol and triglycerides). Anytime—soon after beginning HIV treatment or months later—this reaction could occur. Your immune system becoming overactive may also cause symptoms. You can contact the FDA to report side effects by calling 1-800-FDA-1088 or visiting www.fda.gov/medwatch. Call 1-866-234-2345 to report side effects to Health Canada.

Interactions

Without your doctor's approval, never start, stop, or change the dosage of any medications. Your risk of experiencing serious side effects may increase or your medication's effectiveness may change due to drug interactions. For instance, rifampin, apalutamide, and St. Drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), ergot drugs (such as ergotamine, dihydroergotamine), pimozide, rivaroxaban, certain sedatives (such as midazolam, triazolam), and certain statins (such as lovastatin, simvastatin), among others, are examples of affected drugs. John's wort is one of many. Keep a list of everything you use and give it to your doctor and pharmacist. This list should include both prescription and over-the-counter medications as well as herbal products. Lopinavir/ritonavir can speed up or slow down the removal of other medications from your body, which may affect how they work. Numerous medications interact with lopinavir/ritonavir. Other medications can affect the removal of lopinavir/ritonavir from your body, which may affect how lopinavir/ritonavir works. Additionally, refer to the How to Use section. Cobicistat, orlistat, and a few HIV medications (such as fosamprenavir and tipranavir) are a few examples of products that could interact with this medication. Use an effective barrier method (such as latex or polyurethane condoms or dental dams) during sexual activity to reduce the risk of HIV transmission to others, and discuss additional or alternative reliable methods of birth control with your doctor. Tell your doctor if you notice any new spotting or breakthrough bleeding as these could be indicators that your hormonal birth control isn't working as intended. A pregnancy might result from this. Not all possible drug interactions are listed in this document. This drug may reduce the efficiency of hormonal birth control methods like pills, patches, or rings.

Contraindications

Alterations in the electrical activity and rhythm of your heart. If you are allergic to Kaletra or any of its ingredients, avoid taking it. For more information about medicines you should not take with Kaletra, and consult with your doctor about all other medicines you take. Kaletra may have detrimental side effects, such as: Drug interactions. Check out the section on drug interactions. When taking Kaletra, report any of the following symptoms to your doctor right away: lightheadedness, dizziness, fainting, or a feeling that your heart is beating abnormally. If you are also taking any of the following medications, avoid taking Kaletra. These alterations could be detected on an electrocardiogram (EKG) and could cause life-threatening heart issues. If you already have a history of heart rhythm disorders or other forms of heart disease, or if you take other medications that may affect your heart rhythm while taking Kaletra, your risk for these issues may be higher.

Who manufacturers ritonavir?

Ritonavir is manufactured as Norvir by AbbVie, Inc. The US Food and Drug Administration (FDA) approved ritonavir on March 1, 1996, making it the seventh U.S.-approved antiretroviral drug and the second U.S.-approved protease inhibitor (after saquinavir four months earlier).

Who should not take Kaletra?

KALETRA should not be administered once daily in combination with carbamazepine, phenobarbital, or phenytoin [see Drug Interactions (7)].

What are the side effects of KALETRA?

Diarrhea, nausea, vomiting, stomach upset, gas, headache, and trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.

Does KALETRA have a generic?

Kaletra is FDA approved for the treatment of HIV-1 infection in adult and pediatric patients. Kaletra is a combination of two medications, lopinavir and ritonavir, and is now available in generic. The generic formulations are being manufactured by Lannett and Camber Pharmaceuticals.

How much does ritonavir cost?

The cost for ritonavir oral tablet 100 mg is around $100 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

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Testimonials
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FunctionalDefect Nov 28, 2022, 10:50:36 AM

Telaprevir (Incivek) is not combined with carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, and St. John's wort because they can increase the breakdown of telaprevir and decrease the effectiveness. Telaprevir should not be combined with alfuzosin (Uroxatral), sildenafil (Viagra), and tadalafil (Cialis) because it can increase their blood levels, leading to increased side effects from these drugs. Telaprevir should be used with caution with warfarin (Coumadin) because telaprevir can increase or decrease warfarin (Coumadin) breakdown, increasing or decreasing the effect of warfarin. Telaprevir should be used with caution with arrhythmia medications because the combination can increase the risk of irregular heart rate and rhythm.

user327215 Feb 22, 2016, 3:44:19 AM

Bill Woodard Jan 27, 2019, 5:22:07 PM

AbbVie on March 31 announced a $35 million donation to support COVID-19 relief efforts by healthcare systems and other groups. There was no significant difference in the primary endpoint of 28-day mortality (22.1% lopinavir-ritonavir vs. 21.3% usual care), RECOVERY trial investigators said. AbbVie confirmed it was collaborating with health agencies and institutions globally to determine antiviral activity as well as efficacy and safety of Kaletra against COVID-19. COVID-19: 200 Candidates and Counting To navigate through the >200 potential therapeutic and vaccine options for COVID-19, GEN has grouped the candidates into four broad categories based on their developmental and (where applicable) clinical progress: ● FRONT RUNNER – the most promising therapeutics/vaccines based on clinical progress, favorable data or both. Nucleic acid testing of more than 20 confirmed cases of patients infected with new coronavirus, admitted to hospitals in Zhejiang Province turned negative after taking Kaletra, according to Ascletis Pharma, which is evaluating a combination therapy of its own candidates ASC09 and ritonavir (See below).

jenzz Jul 4, 2021, 2:19:58 AM

The generic formulations are being manufactured by Lannett and Camber Pharmaceuticals. Lopinavir/ritonavir is available in 100/25mg and 200/50mg tablets and a 80/200mg per ml solution. If you have any questions or if we may assist you with your pharmacy needs, please contact us at 800-553-1783 or at [email protected]

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