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nesina vs januvia

Type 2 diabetes is managed with Januvia. Discover the indications, interactions, and side effects.

Other names for this medication:
Steglujan, Velmetia, Janumet, Xelevia, Sitagliptin, Tesavel, Ristaben

Similar Products:
Glimepiride, Saxagliptin, Pioglitazone, Actos, Acarbose, Repaglinide, Onglyza, Micronase, Precose, Glucotrol, Metformin, Glucovance, Glipizide, Prandin


As directed by your doctor, check your blood sugar levels. Do not take two doses of Januvia at the same time. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. If you forget to take a dose, do so right away. Call your doctor or your neighborhood Poison Control Center right away if you take too much Januvia. When Januvia is taken in conjunction with specific other diabetes medications, low blood sugar events may occur more frequently. While taking Januvia, stick to the diet and exercise regimen that have been prescribed. Januvia should only be taken once daily, or as prescribed by your doctor. Talk to your doctor about how to prevent, recognize and manage low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), and problems you have because of your diabetes.
 If you have any of these conditions, tell your doctor as soon as possible. Also, make sure to follow all of your doctor's instructions. The quantity of diabetes medication you require may change when your body is experiencing certain types of stress, such as a fever, trauma (like a car accident), infection, or surgery. You can take Januvia with or without food. Based on the results of your blood tests, your doctor may adjust the dose of Januvia you are taking. To check on the health of your kidneys, your doctor may conduct blood tests periodically. In addition to other diabetes medications, your doctor might advise you to take Januvia. Your doctor will perform routine blood tests to monitor your diabetes, including measuring your hemoglobin A1C and blood sugar levels.


Pay close attention to the meal plan, exercise routine, and medication regimen that your doctor has advised. According to your doctor's instructions, check your blood sugar frequently. Consult your doctor or pharmacist if you have any questions. Keep track of the outcomes and give your doctor a copy. Prior to beginning sitagliptin therapy and each time you receive a refill, read the medication guide that your pharmacist has provided. According to your doctor's instructions, typically once daily, take this medication by mouth with or without food. To reap the greatest benefits from this medication, take it frequently. If your blood sugar readings are excessively high or excessively low, let your doctor know. Your health, kidney function, and treatment response all factor into the dosage. Take it at the same time every day to help you remember to take it. There might be a need to alter your dosage or course of treatment.

Missed dose

Taking two doses at once is not advised. If it is almost time for your next dose, skip the missed dose and take the medication as soon as you remember.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Extreme weakness, hazy vision, perspiration, difficulty speaking, trembling, stomach pain, confusion, and convulsions are a few symptoms of low blood sugar that you might experience.


Consult your pharmacist or local waste disposal company. Unless otherwise instructed, avoid flushing or pouring medications down the drain. Keep out of the bathroom. Pets and children should not have access to any medications. When the product has run its course or is no longer required, dispose of it properly. Place items in a dark, dry place at room temperature.

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Side effects

Rarely will this medication cause a very serious allergic reaction. Although sitagliptin by itself usually does not cause low blood sugar (hypoglycemia), low blood sugar may occur if this drug is prescribed with other diabetes medications. To find out what to do if you miss a meal, speak to your doctor or pharmacist. If you experience any extremely serious side effects, such as signs of pancreatitis (such as nausea/vomiting that won't stop, loss of appetite, or excruciating stomach/abdominal/back pain), seek medical attention right away. However, if you experience any of the following signs of a serious allergic reaction, seek medical attention right away: rash, itching or swelling (especially of the face, tongue, or throat), extreme dizziness, or difficulty breathing. Inform your doctor right away if any of these symptoms appear. If you are lacking these dependable sources of glucose, quickly raise your blood sugar levels by consuming fruit juice or regular soda, or by eating a quick source of sugar like table sugar, honey, or candy. Contact your doctor or pharmacist if you experience any other effects that aren't covered above. For medical advice about side effects in Canada, call your doctor. For medical advice about side effects in the US, call your doctor. It is a good practice to always have glucose gel or tablets on hand to treat low blood sugar. If you consume a lot of alcohol, engage in unusually strenuous exercise, or don't get enough calories from food, your risk of developing low blood sugar increases. Many people using this medication do not have serious side effects. Keep in mind that your doctor has prescribed this medication because they believe it will benefit you more than it will harm you. Hyperglycemia, also known as high blood sugar, causes symptoms such as increased urination, thirst, confusion, drowsiness, flushing, rapid breathing, and a fruity breath odor. Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. If the dosage of your other diabetes medication(s) needs to be lowered, discuss this with your physician or pharmacist. As soon as possible, inform your doctor of the reaction. Tell your doctor right away of any serious side effects, including: signs of kidney problems (such as change in the amount of urine), joint pain, unusual skin blisters, signs of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain). This is not a complete list of possible side effects. Eat meals on a regular schedule and avoid skipping them to help prevent low blood sugar. You can contact the FDA to report side effects at 1-800-FDA-1088 or online at Health Canada can be contacted at 1-866-234-2345 if you wish to report side effects. The diabetes medication(s) you're taking may need to be changed by your doctor.


Drug interactions for Januvia (more information) If you take other medications at the same time as Januvia, it might not work as well. The management of blood sugar can also be impacted by many other medications. Not all possible interactions are covered here. Prescription, over-the-counter, vitamin, and herbal medications as well as other drugs may have an impact on sitagliptin. Tell your doctor about all medicines you start or stop using. Tell your doctor about all of the medications you are taking now as well as any new or discontinued ones. This includes vitamins, herbal products, prescription and over-the-counter medications. If you also use insulin, you might be more prone to low blood sugar.


Do not stop taking your medication. If you have a reaction to any of the ingredients in Januvia, avoid taking the medication. Contact your doctor right away if you experience severe or persistent joint pain. Swelling of the face, lips, tongue, and throat that may make it difficult to breathe or swallow are signs of a serious allergic reaction to Januvia. Tell your doctor if you have or have ever had pancreatitis, an inflammation of the pancreas. Tell your doctor if you have kidney problems or any other medical conditions. If your medication is thought to be the probable cause of excruciating joint pain, your doctor will decide whether to stop taking it.

What is the difference between Januvia and Nesina?

Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine. Lowers your blood sugar. Nesina (alogliptin) is a good add-on treatment for diabetes if your blood sugars are still not controlled, but it doesn't work as well as insulin.

What are the side effects of Januvia?

The most common side effects of JANUVIA include upper respiratory infection, stuffy or runny nose and sore throat, and headache. JANUVIA may have other side effects, including stomach upset and diarrhea, swelling of the hands or legs, when JANUVIA is used with metformin and rosiglitazone (Avandia ®).

Is Nesina the same as JANUVIA?

Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine. Lowers your blood sugar. Nesina (alogliptin) is a good add-on treatment for diabetes if your blood sugars are still not controlled, but it doesn't work as well as insulin.

Is Steglatro the same as Januvia?

What is STEGLUJAN? STEGLUJAN® is a prescription medicine that contains ertugliflozin (STEGLATRO®) and sitagliptin (JANUVIA®). STEGLUJAN is used in adults with type 2 diabetes to improve blood sugar (glucose) along with diet and exercise. STEGLUJAN is not for people with type 1 diabetes.

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nosferatu020289 Feb 24, 2012, 4:33:50 PM

Insulin is a hormone that is necessary to carry glucose from the blood into the cells of the body, where it can be used. This prescription medication contains the active ingredient sitagliptin and belongs to a class of drugs called dipeptidyl peptidase-4 inhibitors. There are several alternative medications for treating type 2 diabetes. Metformin is sometimes prescribed in combination with other diabetes medications or insulin 2.

Luiz Votto Sep 22, 2022, 1:34:37 AM

• You should avoid drinking alcohol while using this medicine because Kaletra liquid already contains alcohol. You should take care of unprotected sex or sharing razors and toothbrushes. Minimum age limit to take Kaletre is 14 days. Ritonavir and Lopniavirboth are antiviral medications that prevent human immunodeficiency virus (HIV) cells from multiplying in human body. Follow your medical expert's directions about any restrictions on beverages, food or activity.

Yasan C Apr 9, 2013, 3:17:53 PM

These findings were based on examination of a small number of pancreatic tissue specimens taken from patients after they died from unspecified causes. They are used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. "At present, the GLP-1 class of drugs is heavily promoted (and prescribed) as having purported advantages that outweigh its risks. Writing in an accompanying commentary, Belinda Gier, PhD, and Peter Butler, MD, from the Larry L. Hillblom Islet Research Center, University of California, Los Angeles, agree, calling the issue of pancreatic cancer "the real crux of the controversy with regard to the safety of GLP-1–based treatment." • And our last report about Victoza was in November 2012: "The Drug-Induced Pancreatitis Safety Problem That Hangs Around Victoza Gets Another Look".

Martijn Vissers Mar 23, 2019, 1:19:59 PM

The use of such products, irrespective of indication, is prohibited and will require a TUE. This is now listed as permitted and a TUE is not required. {openx:269} Diabetic athletes should note that the (World Antidoping Agency) WADA have recently clarified the status of Sitagliptin (Januvia). An athlete wishing to become a bone marrow donor, for which the procedure involves the administration of Filgrastim (Neupogen), Pegfilgrastim (Neulasta), Lenograstim (Granocyte), Molgramsatim (Leucomax) or other granulocyte colony stimulating factor will be required to apply for a standard Therapeutic Use Exemption (TUE).

Eden Whartman Nov 9, 2013, 4:52:45 AM

Other DPP-4 inhibitors such as omarigliptin (Marizev), sitagliptin (Januvia), vildagliptin (Galvus), and saxagliptin (Onglyza) were also associated with a higher risk of fractures compared to placebo. This review included 117 studies with 221,364 patients that had T2D. Voglibose (Voglib), an α-glucosidase inhibitor, significantly decreased the risk of fracture compared to placebo by 97%.

Stefano Bider Apr 10, 2015, 8:35:56 AM

In summary, this recent study found that the DPP-4 inhibitor class of drugs is not associated with IBD; however, DPP-4 inhibitor diabetes drugs, such as Januvia and Onglyza, increase the risk of Crohn's disease (CD). Now, about a year later, the medical journal Annals of Pharmacotherapy has published an article, "Dipeptidyl Peptidase-4 Inhibitors and Inflammatory Bowel Disease Risk: A Meta-analysis", which concludes that DPP-4 inhibitors do not appear to increase the risk of developing IBD -- but goes on to point out that these drugs, such as Januvia and Onglyza, increase the risk of Crohn's disease (CD). In the primary random-effects analysis, DPP-4 inhibitor exposure resulted in a nonsignificant increase in the risk of [inflammatory bowel disease (IBD)] (RR = 1.52; 95% CI = 0.72 to 3.24; I2 = 54.2%).... DPP-4 inhibitor use significantly increased the risk of [Crohn's disease (CD)] (RR = 2.47; 95% CI = 1.36 to 4.48)....

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