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itraconazole side effect

Itraconazole is used to treat several different fungus infections. Talk to your doctor or pharmacist before starting any new medications while taking intraconazole.

Other names for this medication:
Sporanox, Tolsura

Similar Products:
Diflucan, Fluconazole, Grifulvin, Griseofulvin, Ketoconazole, Lamisil, Terbinafine, Nizoral


After you finish the PulsePak, do not take any itraconazole for the next 3 weeks. Always take itraconazole during or right after a full meal. All of the capsules in the PulsePak box will have been consumed after seven days. As directed by your doctor, make sure to finish the entire course of itraconazole. You may take itraconazole twice a day for one week in "pulses," depending on the severity of your infection, or once daily for 12 weeks. Never miss a dose. Itraconazole continues to work inside your nails to help fight the fungal infection even though you are not taking any capsules at this time. Ask your doctor what to do with the missed doses of itraconazole if you forget to take them or miss a dose. If you have ever had liver problems, your doctor should do a blood test to check your condition. Your doctor might advise blood tests to check the health of your liver even if you have never experienced liver issues because itraconazole users have a higher risk of developing liver issues. There is a card with 4 capsules inside each pouch. Each pouch represents a day of treatment, making a total of 7 pouches. Itraconazole PulsePak If you use the PulsePak, you will take itraconazole for one week, go without itraconazole for three weeks, and then repeat the one-week treatment. Fold the card back along the dotted line while keeping an eye on the card's reverse, then peel off the backing to reveal two capsules. Take 2 capsules in the morning and 2 capsules in the evening. Special instructions are provided with the itraconazole PulsePak. One "pulse" (one week of treatment) of itraconazole is provided by the itraconazole PulsePak. "Pulse dosing" is the term for this. For a period of seven days, this entails taking four capsules daily. When your doctor prescribes another pulse treatment, be sure to get your refill before the end of week 4. To effectively treat your fungal nail infection, more than one "pulse" will be required. Either a PulsePak or a bottle of capsules will be delivered to you. The appropriate dose for you will be chosen by your doctor.


In addition, if you have achlorhydria, a condition in which there is little or no stomach acid, or if you take medications that do the same (such as H2 blockers like ranitidine and proton pump inhibitors like omeprazole), you should take this medication with an acidic beverage (such as cola). Antacids may decrease the absorption of this medication. For more information, speak with your physician or pharmacist. Even if symptoms go away after a few days, keep taking this medicine until the entire prescribed amount is gone. Without your doctor's approval, never change this medication's forms or brands. Take this antifungal at regular intervals for the best results. Ask your physician or pharmacist if you have any questions. If you take this medication in cycles, put a reminder on your calendar. Before starting to take itraconazole and each time you get a refill, read the Patient Information Leaflet if one is provided by your pharmacist. You might have to cycle through taking this medication (twice daily for one week, followed by a three-week break) in order to treat certain conditions. If you stop the medication too soon, the infection might come back. As a whole, swallow the capsules. Take itraconazole two hours prior to or one hour following antacid use. As prescribed by your doctor, usually once or twice daily, take this medication by mouth with a full meal. Exactly as directed by your doctor, take this medication. If your condition does not improve or if it worsens, let your doctor know. This medication is available in three different dosage forms that can be taken orally, orally disintegrating tablets, and orally disintegrating capsules. Your medical condition and treatment response will determine the dosage and duration of the course of action. Take this medication at the same time(s) every day to make it easier for you to remember.

Missed dose

To make up for a missed dose, do not take a second one. Skip the missed dose and carry on with your regular dosing schedule, though, if it is almost time for the subsequent dose. When you remember, immediately take the missed dose.


If you think you took too much itraconazole, call your doctor or local poison control center, or go to the nearest hospital emergency room right away.


You should not, however, dispose of this medication in the toilet. The best way to get rid of your medication is instead through a medication take-back program. All medications should be kept out of the sight and reach of children, as many of the containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for small children to open. Store this medication out of children's reach in the tightly closed, original container. If you do not have access to a take-back program, visit the FDA's Safe Disposal of Medicines website at for more information. It should not be kept in the bathroom. Store it at room temperature and away from excessive heat, light, and moisture. For information on take-back programs in your neighborhood, speak with your pharmacist or get in touch with the waste/recycling department of your city. Always lock safety caps and immediately store medications up and away and out of young children's sight and reach. Unused medications should be disposed of in special ways to ensure that pets, children, and other people cannot ingest them.

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Side effects

It is extremely unlikely that this medication will cause a severe allergic reaction. If any rash appears, seek medical attention right away. But if you experience any serious allergic reaction symptoms, such as a rash, itching or swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek medical attention right away. However, you might not be able to distinguish it from a rare rash that could be an indication of a serious allergic reaction. Inform your doctor or pharmacist right away if any of these effects persist or get worse. Contact your doctor or pharmacist if you experience any additional side effects not covered above. For medical advice about side effects in Canada, call your doctor. Call your doctor for medical advice about side effects if you're in the US. Itraconazole can commonly cause a mild rash that is usually not serious. Itraconazole has rarely caused very serious (possibly fatal) liver disease. Many users of this medication report no significant side effects. Nausea/vomiting, diarrhea, headache, stomach upset, or dizziness may occur. Keep in mind that your doctor prescribed this medication because she felt the benefit to you outweighed the risk of side effects. See also Warning section. If you experience any liver disease symptoms, including persistent nausea and vomiting, appetite loss, stomach or abdominal pain, yellowing of the skin or eyes, or dark urine, call your doctor right away. If you experience any severe side effects, such as tingling or numbness in your arms or legs, hearing loss, or mental/mood changes (such as depression), call your doctor right away. This is not a complete list of possible side effects. You can contact the FDA to report side effects at 1-800-FDA-1088 or online at You may report side effects to Health Canada at 1-866-234-2345.


Do not start, stop, or change the dosage of any medicines without your doctor's approval. Drug interactions may alter how your medications function or raise your risk for serious side effects. Examples include, among others, the following: efavirenz, isoniazid, nevirapine, rifamycins (such as rifabutin), and some medications used to treat seizures (such as phenytoin). Itraconazole interacts with many medications. Keep a list of everything you use and give it to your doctor and pharmacist. This list should include both prescription and over-the-counter medications as well as herbal products. Itraconazole removal from your body can be impacted by other medications, which could change how itraconazole functions. Additionally, refer to the Warning and How to Use sections. Also see the Warning section. All possible drug interactions are not covered in this document.


Alcohol may also increase the risk of serious liver problems. Alcohol or marijuana (cannabis) can make you more dizzy. Steer clear of alcohol. Inform your surgeon or dentist of everything you use, including prescription, over-the-counter, and herbal products. If you have allergies to itraconazole, other azole antifungals (like ketoconazole), or any other substances, let your doctor or pharmacist know before you take it. Inform your doctor or pharmacist of your medical history before taking this medication, especially of: liver disease, kidney disease, heart disease (such as heart failure, coronary artery disease, heart valve disease), lung disease (such as chronic obstructive pulmonary disease-COPD), decreased or absent stomach acid (achlorhydria). Before breastfeeding, consult a doctor. With your doctor, go over the advantages and disadvantages. Discuss the use of reliable forms of birth control while taking this medication and for 2 months after stopping treatment. Before you can do it safely, avoid operating machinery, driving, or doing anything else that requires alertness. Only use this medication during pregnancy if absolutely necessary. A developing child could be harmed. Itraconazole passes into breast milk. When taking this medication, older adults may be more susceptible to hearing loss. See also the Warning section. If you use cannabis (marijuana), speak with your doctor. For more information, consult your pharmacist. You may feel lightheaded after taking this medication. This medication should not be used to treat fungal nail infections if you are pregnant or could become pregnant during treatment. Inactive ingredients in this product have the potential to cause allergic reactions or other issues. In order to ensure that they are not pregnant, women of childbearing age should begin taking this medication two to three days after the beginning of their period.

Does itraconazole come in liquid?

Itraconazole capsules and tablets should be taken with a full meal. The oral liquid is best taken on an empty stomach. Take the tablets at the same time each day.

Is itraconazole is a steroid?

Itraconazole is not a steroid. It is an antifungal, which belongs to the group of medicines known as triazoles. It has an excellent efficacy against common fungal infections.

Is itraconazole used for skin infection?

Together with terbinafine and fluconazole, itraconazole belongs to the modern highly effective systemic antifungal drugs with a favorable risk-benefit ratio and for this reason is a preferred therapy option for fungal infections of skin, nails and mucous membranes.

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serkhe Oct 9, 2010, 8:49:25 PM

Description It’s a metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It inhibits the fungal-mediated synthesis of ergosterol, via inhibition of lanosterol 14α-demethylase.

Neomag Jun 6, 2010, 9:14:23 AM Precautions for patients as Itraconazole has the following adverse impacts: [] Cross-hypersensitivity Cardiac effects Hepatic effects Reduced gastric acidity Hepatic impairment Matins Pharma, one of the best PCD Pharma Franchise Company which provides the best of pharmaceutical products including Itraconazole hard gel capsules in franchise on monopoly basis. Itraconazole is an azole antifungal medicine used to treat a variety of fungal infections. ITRACONAZOLE 100 mg is available as ITRO 100 in PCD Franchise by Matins Pharma. Under the PCD Pharma franchise for Itraconazole in India, you will have exclusive rights to sell your products in the agreed territory without any infiltration. Itraconazole was approved in the Unites States of America in 1992, and was also added to the WHO’s list of essential medicines which are needed in a basic health system.

pintu Jan 31, 2019, 9:02:35 AM

Discontinue treatment if hearing loss occurs Most common adverse reactions (incidence ≥ 1%) are nausea, rash, vomiting, edema, headache, diarrhea, fatigue, fever, pruritus, hypertension, abnormal hepatic function, abdominal pain, dizziness, hypokalemia, anorexia, malaise, decreased libido, somnolence, albuminuria, and impotence. » DRUG INTERACTIONS Co-administration of certain drugs that are metabolized by human CYP3A4 enzymes are contraindicated with TOLSURA because plasma concentrations of such drugs are increased, which may also increase or prolong both the pharmacologic effects and/or adverse reactions to these drugs. To report SUSPECTED ADVERSE REACTIONS, contact Mayne Pharma at 1-844-825-8500 or the FDA at 1-800-FDA-1088 or When itraconazole was administered intravenously to healthy human volunteers and dogs, negative inotropic effects were seen. BOXED WARNING • WARNING: CONGESTIVE HEART FAILURE and DRUG INTERACTIONS » CONGESTIVE HEART FAILURE TOLSURA can cause or exacerbate congestive heart failure (CHF).

janis verdi Dec 15, 2010, 6:21:29 AM

For more information, you can mail us at [email protected] Product Details: RAVITRA DS BRAND NAME: RAVITRA DS CONTENT: Itraconazole 200mg Capsules DESCRIPTION Itraconazole is used to treat a variety of fungal infections. tinea pedis, tinea cruris, tinea corporis, tinea manuum, - Pityriasis versicolor, - Onychomycoses caused by dermatophytes and/or yeasts, - Systemic candidiasis, - Cryptococcal infections (including cryptococcal meningitis). It belongs to a class of drugs known as azole antifungals.

andreasw Apr 12, 2020, 11:39:51 PM

Broad spectrum of action with efficacy against Candidiasis, Aspergillosis, Histoplasmosis as well as fungal infectons of toe, nails & onycomycosis. Itraconazole-100 Itraconazole caps are used to treat fungal infection. Itracoanzole is a useful & safe agent in empirical & anti fungal therapy.

wdanford Aug 11, 2021, 4:20:37 AM

In addition, it is significantly less expensive than other methodologies- increasing treatment cost-efficiency. The bioassay offered by MiraVista measures itraconazole blood levels based on the inhibition of fungal growth in the laboratory. Collectively, this supports individualized patient care with therapeutic drug monitoring. Itraconazole is one of the most effective oral antifungals used in veterinary medicine. MiraVista Veterinary Diagnostics offers a bioassay to measure itraconazole blood levels.

Snita Apr 10, 2011, 1:53:40 AM

Itraconazole can be used to treat patients suffering from invasive aspergillosis who were found to be refractory or intolerant to Amphotericin B - Maintenance therapy in AIDS patients to prevent relapse of underlying fungal infection who were found to be refractory or intolerant to first-line systemic anti-fungal therapy is inappropriate or has proved ineffective. It belongs to a class of drugs known as azole antifungals. In immunosuppressed patients suffering from cryptococcosis and in patients with cryptococcosis of the CNS Itraconazole is indicated only if the usually recommended initial therapy seems to be inappropriate or ineffective - Histoplasmosis. For more information, you can mail us at [email protected] Product Details: RAVITRA BRAND NAME: RAVITRA CONTENT: Itraconazole 100mg Capsules DESCRIPTION Itraconazole is used to treat a variety of fungal infections.

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