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indocin suppository

Indomethacin is used to treat a variety of conditions that cause pain, tenderness, and swelling. Serious cardiovascular and digestive issues could result from taking indomethacin.

Other names for this medication:
Indomethacin, Tivorbex

Similar Products:
Zyloprim, Arcoxia, Etoricoxib, Feldene, Colchicine, Naproxen, Allopurinol, Cyclosporine, Motrin, Piroxicam, Naprosyn, Neoral


The medication Indocin SR (extended-release Indocin) shouldn't be used to treat gouty arthritis. Indocin is a nonsteroidal anti-inflammatory drug (NSAID). Indocin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. Indocin may also be used for other conditions not covered in this medication guide. Additionally, bursitis or tendinitis-related shoulder pain can be treated with this medication.


Utilize only the medication form and dosage that your doctor has advised. Information about Indocin dosage in detail The liquid medication must not freeze. Reading the medication guides and adhering to all instructions on the prescription label are essential. If you need surgery, tell your surgeon you currently use this medicine. If you use this medicine long-term, you may need frequent medical tests. The oral suspension (liquid) should be shaken before each dose is taken. Keep your items at room temperature away from heat and moisture. Swallow the extended-release capsule whole and do not crush, chew, break, or open it. Use a medicine dose measuring device (not a kitchen spoon) or the dosing syringe that is provided. Use the smallest dosage necessary to effectively treat your condition. You might have to take a brief break. If you change the brand, strength, or form of Indocin, your dosage requirements might alter.

Missed dose

Never take two doses at once. If it's almost time for your next dose, skip the missed dose and take the medication as soon as you remember.


Canada residents can call a provincial poison control center. Consult your doctor for more details. For specific advice, talk to your doctor. Consult your pharmacist or local waste disposal company. To catch up, do not double the dose. Unless specifically instructed to do so, avoid flushing medications down the toilet or pouring them into drains. Avoid freezing. Don't give this medication to anyone else. Do not keep items in the bathroom. You should skip the missed dose if it is almost time for your next dose. Call 911 if someone has overdosed and is exhibiting serious symptoms like fainting or difficulty breathing. Take the missed dose as soon as you remember if you are prescribed this medication on a regular schedule (not just "as needed"). Keep all medications away from children and pets. Laboratory and/or medical tests (such as blood pressure, complete blood count, liver and kidney function tests) may be performed periodically to monitor your progress or check for side effects. Your flexibility, range of motion, and joint function may all be improved with non-drug arthritis treatment that has been authorized by your doctor, such as weight loss if necessary and strengthening and conditioning exercises. If not, immediately dial a poison control number. When the product has run its course or is no longer required, properly dispose of it. Store at room temperature away from light and moisture. Severe stomach pain, coffee-ground-looking vomit, extreme drowsiness, shallow or slow breathing, confusion, and seizures are all possible overdose symptoms. At the scheduled time, take your next dose. Call 1-800-222-1222 to reach your local poison control center if you're a resident of the US.


Consult your pharmacist or the neighborhood waste management company. Unless otherwise instructed, avoid flushing or pouring medications down the drain. Never freeze. Keep out of the bathroom. Away from children and pets, keep all medications. When the product has run its course or is no longer required, dispose of it properly. Away from light and moisture, keep items at room temperature.

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Side effects

For more details, consult your physician or pharmacist. For medical advice about side effects, contact your doctor. Oral: Common side effects of indomethacin suspension and capsules include the following: headache dizziness vomiting diarrhea constipation ringing in the ears Topical: Common side effects of indomethacin suppositories include the following: headache dizziness vomiting diarrhea constipation irritation of the rectum constant feeling of the need to empty the bowel ringing in the ears Injectable: Side effects of indomethacin injection in infants are uncommon, but may include: bleeding coagulation problems renal failure This is not a complete list of indomethacin side effects. See the "Indomethacin Precautions" section. Indomethacin has been linked to serious side effects. If any side effect bothers you or does not go away, let your doctor know right away. Call the FDA at 1-800-FDA-1088 to report side effects.


Before combining Indocin with any other medications, particularly: If you use an antidepressant, check with your doctor before taking Indocin. Drug interactions with indocin (more information) Not all possible drug interactions are covered in this list. Prescription, over-the-counter, vitamin, and herbal medications as well as Indocin itself may have an impact on other medications. You may bruise or bleed more easily if you take certain antidepressants along with an NSAID. This is not an exhaustive list. cyclosporine, lithium, methotrexate, probenecid, blood thinners like warfarin, coumadin, or jantoven, as well as other NSAIDs like aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, meloxicam, and others.


You may become more groggy or lightheaded if you consume alcohol or marijuana (cannabis). Avoid tanning booths and sunlamps. Inform your surgeon or dentist of everything you use, including prescription, over-the-counter, and herbal products. Inform your doctor or pharmacist if you have any allergies before taking indomethacin, aspirin, or other NSAIDs (such as naproxen, ibuprofen, or celecoxib). Tell your doctor or pharmacist about all of your medical conditions before taking this medication, especially if you have: asthma (including a history of breathing problems getting worse after taking aspirin or other NSAIDs), bleeding or clotting issues, nasal polyps, heart disease (including a history of heart attacks), high blood pressure, liver disease, stomach/intestinal/esophageal problems (including bleeding, ulcers, and recurrent heartburn), and stroke. Women of childbearing age should discuss the benefits and risks of using this medication with their doctor(s) before beginning. Children using this medication should exercise caution. Children may be more sensitive to the side effects of this drug, especially serious liver problems. Consult your doctor before breast-feeding. To learn more, speak with your physician or pharmacist. Your risk of stomach bleeding may increase if you regularly use alcohol and/or tobacco, especially when taking this medication. With your doctor, go over the advantages and disadvantages of the proposed course of action. Until you can do something safely, avoid operating machinery, driving, or doing anything else that requires alertness. Drink plenty of fluids as prescribed by your doctor to avoid dehydration, and inform them right away if you notice a change in the volume of your urine. Between 20 and 30 weeks of pregnancy, if your doctor decides you need to take this medication, you should take it in the shortest amount of time possible at the lowest effective dose. It is not recommended for use in pregnancy from 20 weeks until delivery. When taking NSAIDs, including indomethacin, kidney issues can occasionally arise. Limit alcohol and stop smoking. Don't spend too much time outside. While taking this medication, older adults may be more susceptible to mental/mood changes, kidney issues, heart attacks, strokes, stomach/intestinal bleeding, and kidney problems. Dehydration, heart failure, kidney disease, being an older adult, taking certain medications, and having any of these conditions increase your risk of complications (see also the Drug Interactions section). Talk to your doctor if you are using marijuana (cannabis). Get more information by speaking with your pharmacist. If you are expecting a child or plan to have a child, let your doctor know. If you experience skin blisters or redness, or if you get a sunburn, call your doctor right away. You might feel groggy or lightheaded after taking this medication. This medication enters breast milk and could have negative effects on a nursing infant. This medication has the potential to harm an unborn child and interfere with a normal labor and delivery. You might become more sensitive to the sun as a result of this medication. This medicine may cause stomach bleeding. This product might include inactive components that could lead to allergic reactions or other issues. When outdoors, apply sunscreen and don protective gear. Using this medication after 30 weeks of pregnancy is not advised.

What are the contraindications of indomethacin?

Indomethacin is contraindicated in patients with salicylate hypersensitivity or NSAID hypersensitivity who have experienced asthma, urticaria, or other allergic reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactoid reactions to indomethacin have been reported in such patients.

How is Indocin given?

Indomethacin comes as a capsule, an extended-release (long-acting) capsule, and a suspension to take by mouth. Indomethacin capsules and liquid usually are taken two to four times a day. Extended-release capsules are usually taken one or two times a day.

What are the side effects of Indocid?

Upset stomach, heartburn, headache, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.

What is Indocin suppositories used for?

INDOCIN Suppository is indicated for: Moderate to severe rheumatoid arthritis including acute flares of chronic disease - Moderate to severe ankylosing spondylitis - Moderate to severe ... INDOCIN Suppository is indicated for: Moderate to severe rheumatoid arthritis including acute flares of chronic disease.

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Vadim Ya Jul 4, 2011, 2:51:40 AM

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Jose roberto flore gerardo Feb 6, 2017, 6:50:26 AM

indomethacin (Indocin, Indocin-SR) naproxen (Anaprox, Naprelan, Naprosyn, Aleve) Combining ARBs, ACE inhibitors, or aliskiren (Tekturna) increases risk of hypotension (low blood pressure), hyperkalemia, and reduces kidney function compared to each drug used alone, and there is no additional benefit on preventing end stage kidney disease or death. Metoprolol can mask the early warning symptoms of low blood sugar (hypoglycemia) and should be used with caution in patients receiving treatment for diabetes. Aliskiren and losartan should not be combined in patients with diabetes or with renal impairment.

Omar Bahir Jan 9, 2011, 7:19:32 AM

Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) used for treating fever, pain, and inflammation. Reduction of prostaglandins also diminishes the function of platelets and the ability of the blood to clot. Aspirin inhibits the function of platelets for prolonged periods of time so it is used to reduce the risk of another stroke or heart attack in patients who have had a previous stroke or heart attack. Xarelto, in combination with aspirin, is indicated to reduce the risk of major cardiovascular events (cardiovascular death, myocardial infarction, and stroke) in patients with chronic coronary artery disease or peripheral artery disease. Xarelto is used to reduce the risk of stroke and blood clots in patients with atrial fibrillation not due to a heart valve problem; to treat and reduce the risk of deep vein thrombosis (DVT, blood clots in the veins of the legs) and pulmonary embolism (PE, blood clots in the lungs); and reduce the risk of blood clots in the legs and lungs of patients who have just had hip or knee replacement surgery.

Bogdanovist Jul 6, 2017, 1:47:41 AM

Calcium carbonate – containing antacids, nexium, and omeprazole: they lower chromium absorption and they should be taken 2 – 4 hours apart. Chromium is found in the body in the organic active form in the trivalent state (as a part of GTF) or bound to beta globulin protein. Brewer`s yeast is the best food source of chromium.

rafe Apr 15, 2012, 9:59:17 AM

Voltaren gel, or diclofenac sodium 1%, has been available as a prescription product in America since 2007. Despite the lower absorption, patients should avoid combining oral and topical NSAIDs. A new over-the-counter medication is now available at Sona Pharmacy! Oral NSAIDs to look for on labels include: OTC Oral NSAIDs: Advil (ibuprofen) Aleve (naproxen) Midol Extended Relief (naproxen) Motrin (ibuprofen) Naprosyn (naproxen) Prescription Oral NSAIDs: Celebrex (celecoxib) Feldene (piroxicam) Indocin (indomethacin) Mobic (meloxicam) Toradol (ketorolac) Ketoprofen Etodolac Diclofenac All NSAIDs, topical or oral, should be avoided in patients with cardiac conditions or renal insufficiency. Voltaren Arthritis Pain has advantages over oral NSAIDs due to a decreased amount of absorption into the body.

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