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imitrex nasal spray

Adults with aura or without an aura can take imitrex (sumatriptan) to relieve their migraines. includes interactions, side effects, and indications for imitrex.

Other names for this medication:
Onzetra, Sumatriptan, Zembrace, Tosymra, Treximet, Sumavel

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Rizatriptan, Celecoxib, Azathioprine, Anaprox, Paracetamol, Voveran, Indomethacin, Naprelan, Ditropan, Imdur, Isosorbide, Decadron, Ecosprin, Maxalt, Tylenol, Imuran, Amitriptyline, Voltarol, Cobix


It has an impact on a particular organic compound (serotonin) that leads to the constriction of blood vessels in the brain. It aids in the reduction of pain, nausea, and sensitivity to light and sound in addition to headache and other migraine-related symptoms. By affecting specific brain nerves, it may also reduce pain. Sumatriptan does not lessen the frequency of migraine attacks or prevent further migraines from occurring. Your ability to resume your normal activities is aided by prompt treatment, which may also reduce your need for additional painkillers. Sumatriptan is a member of the triptan drug subclass. Sumatriptan is used to treat migraines.


-Adverse reactions are more likely to occur at higher doses, which may have a greater effect. -It has not been determined whether treating an average of more than 4 headaches in a 30-day span is safe. Detailed Imitrex dosage information Use only after a definitive diagnosis of migraine has been made Oral: Initial dose: 25 mg, 50 mg, or 100 mg orally, once -If some response to first dose occurs, a second dose may be administered at least 2 hours after first dose, if needed -Oral doses of 50 and 100 mg may provide greater relief than 25 mg; however, a 100 mg dose may not provide greater effect than a 50 mg dose Maximum dose: 200 mg per 24 hours Intranasal: Nasal spray To treat migraines in their acute stages, aura or not. The typical adult dose for migraines is:

Missed dose

If your symptoms persist after taking this medication, consult your doctor right away. Imitrex has no set dosage schedule because it is only taken as needed.


Tremors, skin redness in your arms or legs, weakness, lack of coordination, breathing issues, blue lips or fingernails, vision issues, or a seizure (convulsions) are a few overdose symptoms that you might experience. Call the Poison Help hotline at 1-800-222-1222 or go to the emergency room.


Check the product package for instructions on how to store your brand, or ask your pharmacist. Consult your pharmacist or local waste disposal company. The best way to store this drug varies depending on the brand. Unless specifically instructed to do so, avoid flushing medications down the toilet or pouring them into drains. Keep all medications away from children and pets. When the product has run its course or is no longer required, properly dispose of it.

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Side effects

For more information, ask your healthcare provider or pharmacist. If your headaches get worse, your healthcare provider may decide to stop your treatment with sumatriptan. Check out "Drug Precautions." Some people may experience worse headaches (medication overuse headache) if they use/take too much sumatriptan. A serious side effect of sumatriptan is possible. Symptoms of gastrointestinal and colonic ischemic events include sudden or severe stomach pain, stomach pain after eating, weight loss, nausea, vomiting, constipation, or diarrhea that is bloody, fever, and issues with peripheral vascular ischemia, which affects your legs and feet. Peripheral vascular ischemia can cause cramping and pain in your legs or hips, a feeling of heaviness or tightness in your leg muscles, burning or aching pain in your feet or toes while you're resting, numbness, tingling, or weakness in your legs, hives (itchy bumps), swelling of your tongue, mouth, or throat, and headaches. It can also cause numbness, tingling, or color changes in 1 The most typical side effects of sumatriptan tablets are tingling or numbness in your fingers or toes, dizziness, and a warm, hot, burning feeling on your face (flushing). The most typical side effects of sumatriptan nasal spray are dizziness, a warm, hot, burning feeling on your face (flushing), discomfort in your neck, throat, or nose, and sensitivity to loud noises. These are not all the possible side effects of sumatriptan. These severe side effects include gastrointestinal and colonic ischemic events, changes in color or sensation in your fingers and toes (Raynaud's syndrome), and stomach and intestinal problems.


Drug interactions with Imitrex (more information) Not all possible drug interactions are listed here. Prescription and over-the-counter medications, vitamins, and herbal products, among others, may interact with sumatriptan. Tell your doctor if you also use: This isn't a comprehensive list. High levels of serotonin may accumulate in your body while taking Imitrex, a condition known as "serotonin syndrome," which has the potential to be fatal. Herbal products, stimulant or opioid medications, medications for Parkinson's disease, medications for life-threatening infections, medications for nausea and vomiting, or medications to treat depression or other psychiatric disorders


You may become more groggy or lightheaded if you consume alcohol or marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Before using sumatriptan, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before taking this medication, let your doctor or pharmacist know if you have ever had any heart issues (such as chest pain, an irregular heartbeat, or a previous heart attack), liver disease, seizures, a stroke, or a "mini-stroke" (transient ischemic attack), problems with blood circulation (for instance, in your legs, arms, hands, or stomach), hemiplegic headaches, or basilar migraines. Your risk of developing heart issues may increase under certain circumstances. Before breastfeeding, consult a doctor. Discuss the risks and benefits with your doctor. Before you can do it safely, avoid operating machinery, driving, or doing anything else that requires alertness. During pregnancy, this medication should be used only when clearly needed. Limit your alcohol consumption. The negative effects of this medication, particularly elevated blood pressure and heart issues, may be more noticeable in older adults. If you use marijuana (cannabis), talk to your doctor. Talk to your pharmacist for more details. Inform your doctor if you suffer from any of the following conditions: postmenopausal (for women), high blood pressure, high cholesterol, diabetes, family history of heart disease, obesity, smoking, or age over 40 (for men). The risk of heart disease, liver disease, and high blood pressure increases with age. You might feel light-headed or sleepy after taking this medication. Only a small amount of this medication enters breast milk. This product might include inactive components that could lead to allergic reactions or other issues.

What is imitrex used for?

It helps to relieve headache, pain, and other migraine symptoms (including nausea, vomiting, sensitivity to light/sound). Prompt treatment helps you return to your normal routine and may decrease your need for other pain medications. Sumatriptan belongs to a class of drugs known as triptans.

Is Imitrex injection a narcotic?

Sumatriptan is not a narcotic. It is a type of medication known as a 'triptan'. These are selective serotonin receptor agonists (or 5HT agonists) — painkillers specifically used to relieve migraine attacks.

When should sumatriptan be avoided?

You should not use this medicine if you have used an MAO inhibitor (MAOI) such as phenelzine (Nardil®) or tranylcypromine (Parnate®) within the past 2 weeks. Do not use this medicine if you have taken other triptan migraine medicines or ergot-type medicines within the past 24 hours.

Where do I inject Imitrex?

This medicine is given as a shot under your skin (usually on the stomach, thighs, or upper arms). Sumatriptan injection may sometimes be given at home to patients who do not need to be in a hospital or clinic.

How quickly does Imitrex work?

Imitrex tablets typically start to work within 30 minutes, while the nasal spray can start to work in about 15 minutes. Both forms can take up to 2 hours to have their full effect. The Imitrex injection can start working within 5 to 10 minutes.

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Idall Mar 4, 2013, 9:31:47 AM

This Patient Information guide summarizes the most important information about Imitrex Nasal Spray. General information about the safe and effective use of Imitrex Nasal Spray Medicines are sometimes prescribed for purposes other than those listed in Patient Information leaflets. For more information, go to or call 1-888-825-5249.

annonymously Sep 15, 2021, 1:50:39 AM

Just because the medication does not work at one stage, does not mean it may not give you relief in a new stage of your life. Imitrex (sumatriptan) was the first Migraine medication approved to abort an attack. What symptoms are my most troublesome and will Imitrex help them? Do I need brand name Imitrex or can I get a generic?

Faraz Ahmed Sep 7, 2011, 11:50:50 PM

Serotonin syndrome also can make you feel anxious, disoriented or confused, restless, or even cause hallucinations (Heller, 2018). The Imitrex label advises limiting using migraine medications to 10 times a month (FDA, 2013). Drug interactions Sumatriptan cannot be combined with ergot-containing medications.

bem22 Oct 13, 2014, 12:57:40 PM

Dose is 1 at onset, may repeat at 2 hours. Nasal Oxygen for cluster patients, and some migraine patients with clusters of short, quick headache. Treximet (sumatriptan 85 mg, naproxen 500mg).

Azeez Hammed Okikiola Dec 25, 2011, 10:26:40 PM

Excessive tyramine can elevate blood pressure and cause a hypertensive crisis. MAOIs are not recommended for use with medications like pseudoephedrine, phenylephrine, ephedrine, and phenylpropanolamine. Therefore, warfarin therapy, and patients taking NSAIDs should be monitored more frequently with PT/INR testing in individuals who also are taking SSRIs. Since MAOIs inhibit monoamine oxidase, they decrease the breakdown of tyramine from ingested food, thus increasing the level of tyramine in the body.

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