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uptodate hydroxyzine overdose

As a sedative before and after general anesthesia for surgery, hydroxyzine is also prescribed to adults and children in combination with other medications. The drug hydroxyzine belongs to the antihistamine drug class. Hydroxyzine is used to treat itching brought on by allergic skin reactions in both adults and children. The brain's activity is also lowered as a result of it. It is also used to treat anxiety and tension in both adults and children, either on its own or in combination with other drugs. It works by blocking the action of histamine a substance in the body that causes allergic symptoms.

Other names for this medication:
Atarax, Vistaril

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According to Canadian labeling, hydroxyzine is also recommended for use as a premedication before medical procedures like dental surgery in both adults and children. Hydroxyzine is prescribed to treat the symptoms of anxiety and tension brought on by psychoneuroses, as well as to treat organic disease states where anxiety is present. It is also recommended for the treatment of allergic conditions like chronic urticaria, as well as histamine-mediated and allergic-related pruritus. Aside from pregnancy-related nausea and vomiting, it is also used to control motion sickness.


If your anxiety symptoms do not subside or worsen, contact your doctor right away. Information on the dosage of hydroxyzine in detail Do not use this medicine in larger or smaller amounts or for longer than recommended. Observe every instruction on the prescription drug label. Only use hydroxyzine temporarily. Ask your pharmacist for a dose-measuring device if you don't already have one. Use the provided dosing syringe, a dose-measuring spoon, or medicine cup to measure liquid medications. Just before measuring a dose, thoroughly shake the oral suspension (liquid). Store at room temperature away from heat and moisture. As directed by your doctor, take hydroxyzine exactly as directed. This medication should not be taken for more than four months. Periodically, your doctor might adjust your dosage.

Missed dose

To make up for a missed dose, do not take a second one. If, however, it is almost time for the subsequent dose, skip the missed one and carry on with your regular dosing schedule. Take the missed dose as soon as you remember it if your doctor has prescribed that you take hydroxyzine on a regular basis.


Call 911 right away if the victim has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused. Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Information is also available online at Sedation, vertigo, seizures, nausea, and vomiting are all potential signs of an overdose.


You shouldn't flush this medication down the toilet, though. The best way to get rid of your medication is instead through a medication take-back program. All medications should be kept out of the sight and reach of children, as many containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for toddlers to open. Keep this medication tightly closed in its original container away from the reach of children. See the FDA's Safe Disposal of Medicines website ( for more information if you do not have access to a take-back program. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom). To find out about take-back programs in your neighborhood, speak with your pharmacist or get in touch with your city's waste/recycling department. Always lock safety caps and put medications in a secure location right away that is up and away and out of young children's sight and reach to prevent poisoning. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.

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Side effects

For more information, consult your physician or pharmacist. Call your doctor for medical advice about side effects. Dry mouth, drowsiness, nausea, and dizziness are a few of the more frequent side effects of hydroxyzine. Contact the FDA at 1-800-FDA-1088 to report side effects.


Ask your doctor before taking hydroxyzine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Hydroxyzine can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS. Drug interactions involving hydroxyzine (more information) Not all possible interactions are covered here. Prescription and over-the-counter medications, vitamins, and herbal products, among others, may interact with hydroxyzine. When combined with other sleep-inducing medications, this effect may become worse. Inform each of your healthcare professionals about every medication you are currently taking as well as any that you begin or stop using. While receiving treatment with this medication, be sure to let your doctor know about all medications you are currently taking as well as any you begin or stop using.


Alcohol can exacerbate hydroxyzine's side effects. Ask your doctor or pharmacist for a list of the ingredients. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Mention any of the following: antihistamines; azithromycin (Zithromax, ZMax); certain antidepressants like citalopram (Celexa) and fluoxetine (Prozac, Sarafem, Selfemra); medications for anxiety; specific medications for arrhythmias like amiodarone (Cordarone, Nexterone, Pacerone), procainamide, quinidine (in Nuedexta), and sotalol ( Tell your doctor and pharmacist if you have any allergies before taking hydroxyzine, cetirizine (Zyrtec), levocetirizine (Xyzal), any other medications, or any of the ingredients in hydroxyzine preparations. If you are 65 years of age or older, speak with your doctor about the advantages and disadvantages of taking hydroxyzine. Do not drive a car or operate machinery until you know how this medication affects you. ask your doctor about the safe use of alcohol while you are taking this medication. You should be aware that this medication may cause you to feel sleepy, and that older adults should generally avoid taking it because it is less safe than other drugs that can be used to treat the same condition. Inform your doctor if you have a prolonged QT interval (a rare heart condition that may cause irregular heartbeat, fainting, or sudden death), are planning a pregnancy, or are already pregnant. Your doctor may need to change the dosage of your medications or monitor you closely for side effects. If you have or have ever had a slow or irregular heartbeat, low blood levels of potassium or magnesium, heart failure, a heart attack, or heart disease, tell your doctor. Your doctor will probably advise against taking hydroxyzine. Also tell your doctor if you are breastfeeding.

Is hydroxyzine a sleeping pill?

Hydroxyzine (Atarax, Vistaril) is an antihistamine that crosses the blood-brain barrier, meaning it can cause drowsiness. Because of this, it is often prescribed off-label to help individuals with sleep disorders such as insomnia.

Are hydroxyzine and Xanax the same?

Hydroxyzine and Xanax belong to different drug classes. Hydroxyzine is an antihistamine with anticholinergic (drying) and sedative properties and Xanax is an anti-anxiety medication in the benzodiazepine class. A brand name for hydroxyzine is Vistaril.

Is hydroxyzine and Benadryl the same?

Generally speaking, hydroxyzine is an antihistamine related to over-the-counter (OTC) medications like Benadryl and Zyrtec that are used to treat symptoms of allergies and colds such as runny nose and itchy or watery eyes.

Is hydroxyzine the same thing as Xanax?

Hydroxyzine and Xanax belong to different drug classes. Hydroxyzine is an antihistamine with anticholinergic (drying) and sedative properties and Xanax is an anti-anxiety medication in the benzodiazepine class. A brand name for hydroxyzine is Vistaril.

What is hydroxyzine hydrochloride used for?

Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery.

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Andir Aug 10, 2010, 3:43:00 AM

Prothipendyl (brand names Dominal, Timovan, Tolnate), also known as azaphenothiazine or phrenotropin, is an anxiolytic, antiemetic, and antihistamine of the azaphenothiazine group which is marketed in Europe and is used to treat anxiety and agitation in psychotic syndromes. It differs from promazine only by the replacement of one carbon atom with a nitrogen atom in the tricyclic ring system. Prothipendyl is said to not possess antipsychotic effects, and in accordance, appears to be a weaker dopamine receptor antagonist than other phenothiazines.

aonline1 Jan 12, 2015, 4:33:50 PM

Yestilo contains the composition of Hydroxyzine tablets which are used for treating various types of allergy reactions such as itching, swelling and rashes. Before taking this medication, proper consultation from the doctor is a must. Some patients have allergies from Hydroxyzine or taking other medicine for other illnesses such as asthma, kidney and liver infection. Restlessness Confusion Hallucinations Shaking Difficulty Urinating Irregular Heartbeat Contact For Hydroxyzine Tablets Manufacturing and Supply Neurocon Inc has made a reputable place in the top pharma companies of India. Being a top manufacturer and supplier of Hydroxyzine tablets the company is offering PCD Pharma Franchise for Hydroxyzine tablets on a monopoly basis.

newuser0001 Apr 28, 2015, 2:10:39 AM

Taj Pharmaceuticals is reputed manufacturer and Hydroxyzine hydrochloride 10mg Tablets suppliers in India prefer Taj Pharmaceuticals due to the reliability and purity of products. Taj Pharmaceuticals, one of the leading Hydroxyzine hydrochloride 10mg Tablets Manufacturers India brings the best-quality products. The stringent quality-control ensure that every batch of the drug brings a consistent standard.

hasanovuc Jul 15, 2015, 8:25:50 PM

The primary end point was a patient reported global response assessment. Participants met the National Institutes of Health-National Institute for Diabetes and Digestive and Kidney Diseases criteria for IC and reported at least moderate pain and frequency for a minimum of 6 months before study entry. Conclusions: The low global response rates for PPS and hydroxyzine suggest that neither provided benefit for the majority of patients with IC.

Prajwol Aug 8, 2014, 2:30:36 AM

There have been various positive things said about the use of Hydroxyzine including: • Lower anxiety • • Works very fast• Breathing easier than before The cost of Hydroxyzine isn’t disclosed on their website. The time frame may vary based on the dosage that a person is taking, and the severity of the health condition that they use Hydroxyzine for.This medication may be necessary to use daily for various breathing situations. There isn’t enough evidence to determine if doing so could cause some problems for the baby or the fetus. Many people that have high levels of anxiety or tension are asking their doctor for Hydroxyzine by name. Other possible side effects include headaches and dry mouth.

theboy Jan 31, 2020, 9:48:19 AM

Hydroxyzine also is used to treat anxiety and tension, to induce sedation prior to or after anesthesia, and to treat nausea, vomiting, and alcohol withdrawal. Valium (diazepam) is a benzodiazepine used to treat anxiety. Hydroxyzine is an antihistamine with sedative and anticholinergic (drying) properties used to treat itching caused by allergic reactions. Other benzodiazepines include Xanax (alprazolam), Klonopin (clonazepam), Ativan (lorazepam), and Dalmane (flurazepam). Valium is also used to treat agitation, tremors, delirium, seizures, and hallucinations resulting from alcohol withdrawal, and to treat seizures, for relief of muscle spasms in some neurological diseases, and for sedation during surgery.

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