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tretinoin vs isotretinoin

Naturally occurring retinoid analog; also known as all-trans-retinoic acid (aTRA) Oral form used in acute promyelocytic leukemia; topical form used for cutaneous disorders like acne and photoaging The acute promyelocytic leukemia differentiation syndrome could result from oral medication.

Other names for this medication:
Toctino, Panretin

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APL is a condition characterized by an excess of immature white blood cells. Your doctor will decide on your course of treatment following remission. Such APL symptoms as infections, fatigue, and bleeding are assisted by this medication. This drug is used to lessen this disease's symptoms and severity (induce remission). The drug retinol, which is related to vitamin A, is a member of the retinoids drug class. Tretinoin is used to treat a certain type of cancer of the white blood cells (APL-acute promyelocytic leukemia). Tretinoin works by encouraging the development of healthy, mature cells in the bone marrow and blood.


Complete instructions on Tretinoin dosage Read all instruction sheets or medication guides that come with your prescription and follow them exactly. Follow your doctor's dosing instructions very carefully. Away from moisture, heat, and light, store at room temperature. Typically, you won't stop taking tretinoin until you've experienced remission for 30 days, or for a total of 90 days (whichever comes first). Follow the medication's instructions to the letter. You'll require regular medical exams.

Missed dose

Do not take a double dose to make up for a missed one. To continue with your regular dosing schedule, skip the missed dose if it is almost time for the next one. If you miss a dose, take it as soon as you remember.


Residents of Canada can dial a regional poison control center. For more information, speak to your doctor. Consult your pharmacist or the neighborhood waste management company. In order to catch up, do not double the dose. Unless otherwise instructed, avoid flushing or pouring medications down the drain. Do not share this medication with others. Do not keep items in the bathroom. If it is near the time of the next dose, skip the missed dose. Call 911 if someone has overdosed and is exhibiting serious symptoms like fainting or difficulty breathing. If you miss a dose, take it as soon as you remember. Keep kids and pets away from all medications. To track your progress or look for side effects, laboratory and/or medical tests should be run, including complete blood counts, liver function tests, blood cholesterol and triglyceride levels, and pregnancy tests. Otherwise, call a poison control center right away. Properly discard this product when it is expired or no longer needed. Place items in a dark, dry place at room temperature. At the scheduled time, take your subsequent dose. Call 1-800-222-1222 to reach your local poison control center if you're a resident of the US.


Speak with your pharmacy or the neighborhood waste removal service. Unless specifically instructed to do so, never flush or pour medications down the drain. Place nowhere near a bathroom. Keep all medications away from children and pets. When the product is no longer needed or has expired, dispose of it properly. Store at room temperature away from light and moisture.

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Side effects

If any of the following apply to you: For medical guidance on side effects, call your doctor. Typical negative effects could be: Observe the advice of your doctor to the letter. If you experience any of the following symptoms of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat, seek emergency medical attention. Although RA-APL is treatable, you might need to temporarily stop taking tretinoin. Retinoic acid-APL (RA-APL) syndrome is a potentially fatal condition that some tretinoin users experience. If you experience any of the early signs of RA-APL syndrome, including weight gain, shortness of breath, fever, or lightheadedness, call your doctor right away. There may be additional side effects; this is not a comprehensive list. Numerous organs in your body, such as the lungs, liver, or kidneys, can fail as this syndrome worsens. Side effects of retinoids (more information) You may report side effects to FDA at 1-800-FDA-1088. a feeling of impending dizziness; mouth and throat ulcers; red or swollen gums; burning mouth pain; difficulty swallowing; increased pressure inside the skull; severe headaches; nausea; vision issues; pain behind the eyes; kidney problems; little or no urination; swelling in the feet or ankles; fatigue; liver problems; upper stomach pain; loss of appetite; jaundice (yellowing of the skin or eyes); Bleeding; swelling in your hands or feet; abnormal liver function tests; flushing (sudden warmth, redness, or tingly feeling); dry mouth, nose, or throat; stomach pain, nausea, vomiting, diarrhea; bone pain; rash; or mouth sores.


Without your doctor's approval, never start, stop, or modify the dosage of any medications. Drug interactions could alter how your medications function or raise the possibility of serious negative side effects. Keep a list of everything you use, including prescription, over-the-counter, and herbal products, and give it to your doctor and pharmacist. Some products that may interact with this drug include: drugs that prevent bleeding (anti-fibrinolytic drugs such as aminocaproic acid, aprotinin, tranexamic acid), hydroxyurea, ketoconazole, "mini-pill" (progesterone birth control pills that do not contain estrogen), tetracyclines, sulfisoxazole containing drugs, vitamin A. Not every possible drug interaction is covered in this document.


(See also section titled "Warning"). You may feel more lightheaded after consuming alcohol or marijuana (cannabis). Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Tell your doctor or pharmacist if you have any allergies before taking tretinoin, including those to it, other retinoids like isotretinoin, medications related to vitamin A, or any other allergies you may have. Inform your doctor or pharmacist about your medical history before taking this medication, especially of: liver disease, high cholesterol/triglycerides (blood fats), and mental/mood issues (such as depression). Children may be more sensitive to this medication's side effects, especially if they also take tetracycline medication. Consult your doctor before breast-feeding. Avoid giving blood while taking this medication and for at least one month after stopping it. Till you can do it safely, avoid operating machinery, operating a vehicle, or performing other tasks that call for alertness or sharp vision. Inform your doctor as soon as possible if you find out you are pregnant or suspect you might be. It is unknown whether this medication enters breast milk. Limit alcoholic beverages. Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules. Soy allergies can occur in some individuals with peanut allergies. Consult your doctor about effective birth control methods. If you use marijuana (cannabis), consult your physician. Get more information by speaking with your pharmacist. If your child experiences a severe headache, nausea or vomiting, or vision issues, call your doctor right away. You could experience severe headaches, blurred vision, or dizziness from this medication. Due to the possibility of birth defects and harm to an unborn child, it is not advised to use this medication during pregnancy. These inactive ingredients, which include soybean and paraben preservatives, may be present in this product and may lead to allergic reactions or other issues. This will eliminate the chance of a pregnant person receiving your blood. To avoid getting pregnant, combine two reliable birth control methods.

What does tretinoin do to the skin?

One of the tretinoin creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by the damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and slowing down the way the body removes skin cells that may have been harmed by the sun.

Is Amzeeq a tretinoin?

Amzeeq (minocycline) and Retin-A (tretinoin) Cream and Gel are used for the topical treatment of acne vulgaris. Amzeeq is used to treat inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 9 years of age and older. Amzeeq and Retin-A belong to different drug classes.

Is there A generic brand of tretinoin?

Tretinoin, both in its generic form and as brand name Retin-A, is widely recognized as a potent topical prescription medication (meaning, you apply it to your skin) for fighting acne and signs of aging, such as wrinkles (Yoham, 2020).

Can I use hydroquinone with tretinoin?

You can use Hydroquinone and Retin-A together to brighten your skin. The 2 creams can be used together for 3 months at a time, then you need to take a break.

Is Altreno the same as tretinoin?

Altreno (tretinoin) Lotion, 0.05% is a prescription medicine used on the skin (topical) to treat people with acne (blackheads, whiteheads, and other pimples).

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Karamzik Nov 23, 2011, 4:29:58 AM

Minimize exposure to the sun and use a sunscreen with an SPF of at least 30. Do not get Tretinoin in your mouth, eyes, vagina, or the corners of your nose. Women who are pregnant or breastfeeding cannot use Tretinoin.

KyleMit Mar 18, 2011, 4:27:07 AM

Apply only to the affected areas, not to the surrounding, healthy skin. Make sure to do your research to find the best deal for you. Due to exposure to UV light Skin exposure manifests as freckle-like patches or rough lesions, wrinkles, and dark. Reduces papules, pustules and comedones and is suitable for long term maintenance therapy. It offers considerable improvements in clinical lesion counts, comedones, patient satisfaction, and global assessments when it is applied topically to the skin.

Toppka May 6, 2016, 12:11:20 AM

Spend a few minutes too long in the sun and there’s a real risk of your skin looking red and sunburned by the end of the day. Instead, the best time to apply tretinoin is at nighttime — usually 20 to 30 minutes after cleansing your face before you go to bed. After a few months of tretinoin use, studies show that skin gradually begins to adjust to sunlight and photosensitivity returns to normal. Tretinoin Can Make Your Skin More Sensitive to Sunlight Your skin can become significantly more sensitive to sunlight while using tretinoin, especially during the beginning of treatment.

Casey French Nov 20, 2016, 12:36:10 PM

For consumers who wish to buy A Ret Gel online in the USA, UK, AU and overseas with assurance of safety and reliability, Skinorac is the ideal place. We have been offering complete range of Tretinoin cream with complete advice, guidance and direction of use. We have years of experience dealing with healthcare products and lifestyle products. There are various pharmacy websites who offer to sell tretinoin online but Skinorac stands out among them as it is one of the most trusted suppliers of tretinoin and other healthcare products.

user211571 Mar 7, 2014, 4:28:33 AM

If the degree of local irritation warrants, patients should be directed to use the medication less frequently, discontinue use temporarily, or discontinue use altogether. To report SUSPECTED ADVERSE REACTIONS contact FDA at or call 1-800-FDA-1088. Precautions: Exposure to sunlight, including sunlamps, should be minimized during the use of Tretinoin Cream and Gel, and patients with sunburn should be advised not to use the product until fully recovered. If these effects occur, treatment should be discontinued or adjusted to a level the patient can tolerate. Patients who have considerable sun exposure due to occupation and those with inherent sensitivity to the sun should exercise particular caution.

Dendy Octavian Dec 8, 2013, 5:23:03 AM

If your skin is sensitive, you may want to wait 20-30 minutes after washing your face before you apply this treatment. The formulas may contain some or all of the ingredients listed above. The Acne treatment is free of the following ingredients: Gluten Parabens Phthalates Sulfate Synthetic fragrance What if I am currently using a product containing a retinoid (tretinoin, Retin-A®, Tazorac®, or over-the-counter retinol)? If you are having any treatments such as a facial, electrolysis, or waxing, please inform the individual providing the service that you are using a product with tretinoin. While using the Acne Treatment, please do not use any other treatments on your face that contain a retinoid (including over-the-counter products) What are the most common side effects of this medication: You may experience side effects with this medication.

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