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glycopyrronium vs tiotropium

A long-acting bronchodilator called tiotropium is used to treat chronic obstructive pulmonary disease (COPD).

Other names for this medication:
Inspiolto Respimat, Stiolto, Spiriva Respimat, Spiriva

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A combination tiotropium and metered inhalation spray is indicated for maintenance of COPD. A tiotropium inhalation spray is indicated for the maintenance of bronchospasm in COPD, to prevent exacerbations of COPD, and to treat asthma in patients 12 or more years old. A tiotropium metered inhalation spray is indicated for the maintenance of bronchospasm in COPD, to prevent exacerbations of COPD, and to treat asthma in patients 6 or more years old. For the maintenance of bronchospasm in COPD and to stop COPD exacerbations, tiotropium powder for inhalation is recommended.


Follow the directions on your prescription label carefully. Tiotropium should only be taken as directed. Tiotropium (Spiriva Respimat) should be taken twice a day, as directed. The suggested dosage of tiotropium (Spiriva) is two HandiHaler inhalations of the powder inside one tiotropium capsule, once daily. Treatment for COPD involves two daily inhalations of Spiriva Respimat 2.5 mcg, while treatment for asthma (6 years and older) involves two daily inhalations of Spiriva Respimat 1.25 mcg.

Missed dose

Avoid taking double doses. Tiotropium should only be taken once every 24 hours. If, however, it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Tiotropium should be taken as soon as you recall missing a dose.


However, seek immediate medical attention if overdose is thought to have occurred. If tiotropium is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. If you take too much tiotropium, call your doctor or the nearest poison control center right away, or go to the hospital for emergency care.


The remaining 2 capsules should be taken over the course of the following 2 days after the initial capsule has been taken. When it comes to disposing of any medication you no longer need, consult a healthcare professional. Capsules that are accidently exposed to air and not intended for immediate use should be discarded. Information about the exact dosage of tiotropium Avoid storing unused or outdated medications. prevent freezing. Keep children's reach at a distance. Until you're ready to use the medication, keep the capsules in the blister pack. Use the capsule as soon as you have cracked open a blister. When you're ready to take a capsule out and place it in the HandiHaler® device, only open one blister at a time. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Side effects

Tiotropium may also cause side effects like upper respiratory infections, dry mouth, sinus infections, sore throats, non-specific chest pain, urinary tract infections, indigestion, runny noses, constipation, increased heart rates, and blurred vision. Look at "Drug Precautions." If you experience any side effects that bother you or do not go away, let your doctor know right away. Serious adverse effects from tiotropium are possible.


If you are unsure whether one of your medications is an anticholinergic, consult your doctor or pharmacist. When you receive a new prescription, keep a list of your current medications on you to show your doctor and pharmacist. Be aware of the medications you take. The way in which tiotropium functions may be impacted by some of your other medications or dietary supplements. Inform your doctor of all the medications you take, including prescription and over-the-counter drugs, eye drops, vitamins, and herbal supplements. Anticholinergic medication is tiotropium. While using tiotropium, including ipratropium, you shouldn't take any other anticholinergic medications.


Avoid getting the tiotropium capsule's powder in your eyes. Do not use tiotropium if you are allergic to tiotropium, ipratropium (Atrovent), or any of the ingredients in tiotropium. Make a call to your physician if this occurs. Tiotropium should be stopped immediately if you experience any of these signs of urinary retention. Stop taking tiotropium if you experience any of these symptoms, and contact your physician right away. Tiotropium should be stopped immediately if your breathing suddenly becomes worse. You should also call your doctor or visit the emergency room of the nearest hospital if this happens. increased eye pressure that is either new or worsening (acute narrow-angle glaucoma). urinary retention that has developed or worsened. If you experience these symptoms, you should exercise caution when performing tasks like operating a machine or driving a car. Bronchospasm is the sudden narrowing and obstruction of the lungs' airways. If you experience any of these allergic reaction symptoms, stop taking tiotropium and contact your doctor right away. You can also go to the nearest hospital emergency room if you have difficulty breathing or swallowing. Raised red patches on your skin (hives) itchy rash swelling of the lips, tongue, or throat Eye drops alone may not be effective in treating the symptoms of acute narrow-angle glaucoma, which also include eye pain, blurred vision, and seeing colored or haloed images. You may have trouble passing urine or experience painful urination as signs of a blocked bladder or an enlarged prostate. Dizziness and blurry vision are side effects of tiotropium. Serious side effects of tiotropium can include allergic reaction. Your vision may get blurry and the pupil in your eye may get larger (dilate).

What is the brand-name for tiotropium?

Tiotropium inhalation powder is available as the brand-name drug Spiriva.

Is tiotropium a LAMA or LABA?

In addition, these bronchodilators improve exercise performance [5, 6]. Currently available LAMA comprises tiotropium, glycopyrronium, aclidinium and umeclidinium and LABA includes salmeterol, formoterol, indacaterol, vilanterol and olodaterol.

What is tiotropium used to treat?

Tiotropium is used to treat chronic obstructive pulmonary disease (COPD). COPD is a lung disease that also includes chronic bronchitis (swelling of the tubes leading to the lungs) and emphysema (damage to the air sacs in the lungs).

Can tiotropium be given orally?

Remind patients that the contents of SPIRIVA capsules are for oral inhalation only and must not be swallowed. Instruct patients always to store SPIRIVA capsules in sealed blisters and to remove only one SPIRIVA capsule immediately before use or its effectiveness may be reduced.

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locdev Jan 1, 2019, 9:02:53 AM

COPD is a chronic inflammatory lung disease, in which airways become blocked, leading to wheezing and shortness of breath. Symptoms arise when significant lung damage has already occurred and tend to worsen over time. Due to its bronchodilator properties, tiotropium can ease several COPD symptoms, including shortness of breath, wheezing, coughing, and chest tightness. Now, the company is planning to launch the medicine in Ireland, Sweden, Norway, and Finland as Tiogiva, in Denmark, the Netherlands, and Spain, as Tavulus, and as Tiotropium Glenmark in Germany.

Duncan Morris Feb 2, 2017, 8:56:16 AM

Anoro Ellipta is a combination of a long-acting muscarinic antagonist (LAMA) and a long-acting… GlaxoSmithKline (GSK) and Innoviva presented positive results from a Phase 3b study investigating the efficacy and safety of Anoro Ellipta (umeclidinium/vilanterol, or UMEC/VI) in patients with moderate chronic obstructive pulmonary disease (COPD) who continued to experience symptoms while on tiotropium (bronchodilator) monotherapy.

thomastiger Sep 4, 2010, 2:04:55 AM

It does not provide medical advice, diagnosis or treatment. Tiotropium is a LAMA (long-acting muscarinic antagonist) bronchodilator, and olodaterol is a LABA (long-acting beta2-agonist) bronchodilator. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. ), new COPD symptoms appear or existing ones worsen, or other more severe reactions are evident.

arejaye Aug 25, 2015, 2:33:10 PM

In long-term clinical studies (12 weeks to 1 year) in patients with moderate to severe COPD, OD indacaterol 150 or 300 μg improved lung function (primary endpoint) significantly more than placebo, and improvements were significantly greater than twice-daily formoterol 12 μg or salmeterol 50 μg, and noninferior to OD tiotropium bromide 18 μg. However, in people with COPD who remain symptomatic on treatment with indacaterol, adding a long-acting muscarinic antagonist (LAMA) is the preferable option. Indacaterol was well tolerated at all doses and with a good overall safety profile. It is rapidly acting, with an onset of action in 5 minutes, like salbutamol and formoterol but with a sustained bronchodilator effect, that last for 24 hours, like tiotropium.

pixelscreen Oct 17, 2017, 6:19:25 AM

A first patient has been enrolled in a Phase 4 study of the effectiveness of Yupelri (revefenacin) against Spiriva (tiotropium) in improving lung health in adults with severe chronic obstructive pulmonary disease (COPD). The respective safety of these two approved, once-daily COPD maintenance treatments will also be evaluated.

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