Gemfibrozil is a lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
Other names for this medication:
Lopid
Similar Products:
Zocor, Fenofibrate, Tricor, Lipitor, Ezetimibe, Simvastatin, Zetia, Rosuvastatin, Crestor, Atorvastatin
Never combine two gemfibrozil doses. Gemfibrozil is a pill that must be taken orally twice daily, 30 minutes before breakfast and dinner. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. When you realize you missed a dose, take it right away. Exactly as directed, take gemfibrozil.
Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. Even if you feel good, keep taking the gemfibrozil. Never stop taking gemfibrozil without consulting your doctor first. Never take it in larger or smaller amounts or more frequently than directed by your doctor. Eat a low-fat, low-cholesterol diet. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Gemfibrozil is available as a tablet that needs to be swallowed. However, gemfibrozil does not treat high triglyceride levels or low HDL levels. It is usually taken twice a day, 30 minutes before the morning and evening meals. Take gemfibrozil every day at roughly the same time. Take gemfibrozil exactly as directed. Ask your doctor or pharmacist for more details if you think this medication may be prescribed for other conditions. You can also visit the National Cholesterol Education Program (NCEP) website for additional dietary information at http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.
To catch up, don't double the dose. You should skip the missed dose if it is almost time for your next dose. Take the missed dose as soon as you remember it if you miss it. At the scheduled time, take your next dose.
Call the Poison Help hotline at 1-800-222-1222 or go to the emergency room.
Keep away from light and moisture at a temperature below 30 degrees Celsius. Keep away from children's reach.
Ask your doctor or pharmacist for more information. Call your doctor for medical advice about side effects. Heartburn, stomach pain, nausea, vomiting, diarrhea, and fatigue are typical side effects. Gemfibrozil may also result in drowsiness and blurred vision. Before you know how gemfibrozil affects you, avoid driving or using heavy equipment. The side effects of gemfibrozil are not entirely covered in this list. Contact the FDA at 1-800-FDA-1088 to report side effects.
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Drug interactions could alter how your medications function or raise the possibility of serious negative side effects. Among other medications, elagolix, irinotecan, pioglitazone, selexipag, and a specific combination product used to treat chronic hepatitis C (ombitasvir/paritaprevir/ritonavir/dasabuvir) are examples of those that are affected. Keep a list of everything you use, including herbal products, prescription and over-the-counter medications, and give it to your doctor and pharmacist. Asunaprevir, "blood thinners" (such as warfarin), colchicine, repaglinide, and "statin" drugs (such as atorvastatin, lovastatin, and simvastatin) are a few products that could interact with this medication. Not every possible drug interaction is covered in this document. This medication can slow down the removal of other medications from your body, which may affect how they work.
Tell your doctor if you are taking dasabuvir (in Viekira Pak), simvastatin (in Zocor, in Vytorin), or repaglinide (in Pradin, in Prandimet). Be sure to mention any of the following medications: atorvastatin (Lipitor, in Caduet), bosentan (Tracleer), colchicine (Colcrys, Mitigare, in Col-Probenecid), dabrafenib (Tafinlar), enzalutamide (Xtandi), ezetimibe (Zetia, in Vytorin), fluvastatin (Lescol), glyburide Inform your doctor and pharmacist if you have any drug or ingredient allergies before taking gemfibrozil. Call your doctor if you become pregnant while taking gemfibrozil. Other medications may also interact with gemfibrozil, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. if you are taking colestipol (Colestid), take this medication 2 hours before or 2 hours after gemfibrozil. tell your doctor if you have kidney, liver, or gallbladder disease. Your physician might need to adjust the dosage of your medications or keep a close eye on you for side effects. Inform your doctor if you are pregnant, intend to become pregnant, or are nursing a baby as they may advise against taking gemfibrozil. Tell your doctor and pharmacist what prescription and non-prescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor will probably advise you not to take gemfibrozil while taking any of these medications.
Which of the following is a serious side effect of gemfibrozil therapy?
Serious side effects of gemfibrozil include: Severe stomach/abdominal pain. Persistent nausea or vomiting. Yellowing eyes or skin (jaundice)
Can gemfibrozil be crushed?
This drug should be taken before meals. Take it 30 minutes before your morning and evening meals. Do not cut or crush the tablet.
What is the difference between gemfibrozil and atorvastatin?
Atorvastatin was more effective (P < 0.001) in lowering LDLc, non-HDLc, and apoB and in achieving treatment goals, whereas gemfibrozil lowered triglyceride levels more effectively (P < 0.001) and increased LDL size (from 25.59 +/- 0.06 to 25.69 +/- 0.06 nm; P < 0.05).
Who should not take gemfibrozil?
a patient who is producing milk and breastfeeding. a progressive liver disease called primary biliary cholangitis. chronic kidney disease stage 4 (severe) chronic kidney disease stage 5 (failure)
Can you buy gemfibrozil over the counter?
Can I Buy Gemfibrozil Online? Gemfibrozil is a prescription medication in the United States. Because of this gemfibrozil OTC (over the counter) cannot be dispensed by pharmacies and one cannot just buy gemfibrozil online as the first step is getting a consultation with a medical provider.
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Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. It is not known if Orilissa passes into your breastmilk. Before you take Orilissa, tell your healthcare provider about all of your medical conditions, including if you: have or have had broken bones have other conditions or take medicines that may cause bone problems have or have had depression, mood problems or suicidal thoughts or behavior have liver problems think you may be pregnant. Your healthcare provider may advise you to change the pills you take, or your method of birth control. Especially tell your healthcare provider if you take: birth control pills.
Anaemia, leucopenia, thrombocytopenia, eosinophilia and bone marrow hypoplasia have been reported rarely (see section 4.8). If the response is insufficient after 3 months of therapy at recommended doses treatment should be discontinued and alternative treatment methods considered. Cases of cholelithiasis have been reported with gemfibrozil therapy. This medicinal product contains less than 1 mmol sodium (23 mg) per tablet.
Of patients with Genotype 1 with liver scarring, 93% to 100% of patients achieved SVR. Exviera is an antiviral medicine used in combination with other medicines to treat chronic hepatitis C. It has been approved within the NHS for treatment of people with Genotype 1 in combination with Viekirax, with or without ribavirin. Contraindications include but are not limited to: ethinylestradiol-containing medicinal products such as those contained in most combined oral contraceptives or contraceptive vaginal rings; carbamazepine, phenytoin, phenobarbital, efavirenz, nevirapine, etravirine, enzalutamide, mitotane, rifampicin, St. John’s Wort and gemfibrozil.
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While it is primarily active at the PPARδ receptor, it is considered a pan agonist with activity at PPARα and PPARγ receptors. Sodelglitazar, formerly known as GW 677954, is a thiazole PPARδ receptor agonist developed by GlaxoSmithKline. Phase 2 studies were terminated prior to completion due to safety findings in rodent studies.