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Famotidine
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famotidine medication template

Famotidine is a histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.

Other names for this medication:
Duexis, Pepcid, Pepcid Complete, Fluxid, Duo Fusion, Good Sense Acid Reducer

Similar Products:
Prevacid, Loperamide, Omeprazole, Mesalamine, Pentasa, Lansoprazole, Metoclopramide, Maxolon, Aciphex, Pantoprazole, Motilium, Rabeprazole, Imodium, Reglan, Prilosec, Mebeverine, Colospa

Description

Famotidine completely inhibits the action of histamine on H2- receptors of parietal cell. A histamine H2-receptor antagonist is famotidine. It blocks the secretion of gastric acid at rest and when pentagastrin is present. Since famotidine slowly separates from the H2-receptor, its H2-receptor antagonistic activity is slowly reversible.

Dosage

Take it only as directed by your doctor, and never take more, less, more frequently, or for a longer period of time. Do not take more than two tablets, capsules, or chewable tablets of over-the-counter famotidine in 24 hours and do not take over-the-counter famotidine for longer than 2 weeks unless your doctor tells you that you should. Ask your doctor or pharmacist to explain any instructions you do not understand, and carefully follow any instructions on your prescription label or the package label. Stop using over-the-counter famotidine and make an appointment with a doctor if heartburn, acid indigestion, or sour stomach symptoms persist for more than two weeks. It is usually taken once daily at bedtime or two to four times a day. Typically, it is taken once or twice per day. There are three oral dosage forms of over-the-counter famotidine: tablets, chewable tablets, and capsules. Tablets and liquid suspensions of famotidine are available by prescription for oral consumption. Before using the liquid, shake it vigorously for 5 to 10 seconds to evenly distribute the medication. Swallow the chewed tablet with a full glass of water. With a full glass of water, swallow the pills and tablets. Famotidine must be taken exactly as prescribed. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. The chewable tablets should be thoroughly chewed before being inhaled. It is taken 15 to 60 minutes before consuming foods or beverages that may cause heartburn in order to reduce symptoms. Keep eating normally unless your doctor instructs you otherwise.

Missed dose

To make up for a missed dose, do not take a second one. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Famotidine prescribed by your doctor should be taken as soon as you remember a missed dose. Take the missed dose of over-the-counter famotidine as soon as you remember it if your doctor has prescribed it to you on a regular basis. Over-the-counter famotidine is usually taken as needed.

Overdose

Call emergency services at 911 right away if the victim has fallen, experienced a seizure, is having trouble breathing, or cannot be roused. Dial 1-800-222-1222 to reach the poison control hotline in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help.

Storage

Inactive famotidine liquid should be discarded after 30 days. Avoid letting the liquid freeze. This medication should not, however, be flushed down the toilet. Instead, using a medication take-back program is the best way to get rid of your medication. As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Store this medication out of children's reach in the tightly closed, original container. If you do not have access to a take-back program, visit the FDA's Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for more details. It should not be kept in the bathroom. Store it at room temperature, away from sources of extreme heat and moisture. For information on take-back programs in your neighborhood, speak with your pharmacist or get in touch with the waste/recycling department of your city. Always lock safety caps and put medication in a secure spot right away that is up and out of the way and out of reach of young children to prevent poisoning. http://www.upandaway.org Unused medications must be disposed of carefully to prevent pets, kids, and other people from ingesting them.

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Side effects

Rare side effects include headache, drowsiness, drooling, constipation, diarrhea, dry mouth, nausea, vomiting, tachycardia, high blood pressure, and tachycardia.

Interactions

Additionally, famotidine is prescribed to treat acute gastritis and acute exacerbations of chronic gastritis. It is recommended to take famotidine for Zollinger-Ellison syndrome, acute stress ulcers, anastomotic ulcers, and gastric ulcers.

Contraindications

It's a good idea to not drink alcohol. If your doctor has told you to, you shouldn't take other stomach acid reducers. Milk of Magnesia, Rolaids, and Tums are some of the antacids that you may take. It can increase the risk of damage to your stomach.

What is Famotidine used for?

Famotidine is used to treat stomach ulcers (gastric and duodenal), erosive esophagitis (heartburn or acid indigestion), and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus.

Can PEPCID be given IV push?

IV Push: To prepare famotidine intravenous solutions, aseptically dilute 2mL of famotidine injection (solution containing 10mg/mL) with 0.9% Sodium Chloride Injection or other compatible intravenous solution (see Stability) to a total volume of either 5 mL or 10 mL, and inject over a period of not less than 2 minutes.

Why was famotidine taken off the market?

SUMMARY: The Food and Drug Administration (FDA or Agency) has determined that PEPCID (famotidine) tablet, 20 milligrams (mg) and 40 mg, was not withdrawn from sale for reasons of safety or effectiveness.

Why do you give famotidine at night?

The drug was able to keep intragastric pH above 4 units during almost 50% of the whole 24-hour period. These results confirm that famotidine is a powerful and long-acting H2 blocker that relieves gastric acidity during the night and morning hours when administered as a single bedtime dose of 40 mg.

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Testimonials
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Matt Carron Oct 29, 2015, 12:51:04 PM

The clinical trials primarily enrolled patients less than 65 years of age without a prior history of gastrointestinal ulcer. DUEXIS (IBUPROFEN AND FAMOTIDINE) INDICATIONS AND USAGE DUEXIS (ibuprofen and famotidine), a combination of the NSAID ibuprofen and the histamine H-receptor antagonist famotidine, is indicated for the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk of developing upper gastrointestinal ulcers, which in the clinical trials was defined as a gastric and/or duodenal ulcer, in patients who are taking ibuprofen for those indications.

starskynatasha Aug 3, 2014, 1:34:22 PM

The clinical trials primarily enrolled patients less than 65 years of age without a prior history of gastrointestinal ulcer. DUEXIS (IBUPROFEN AND FAMOTIDINE) INDICATIONS AND USAGE DUEXIS (ibuprofen and famotidine), a combination of the NSAID ibuprofen and the histamine H-receptor antagonist famotidine, is indicated for the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk of developing upper gastrointestinal ulcers, which in the clinical trials was defined as a gastric and/or duodenal ulcer, in patients who are taking ibuprofen for those indications.

Hydrographer Aug 9, 2020, 5:47:08 PM

For treatment of mild symptoms: The recommended dosage is 20 mg twice daily, for 6 to 12 weeks. Famocid may also be used to lower the chance of occurring duodenal ulcers again. Do not take any medicine after the expiry date, which is mentioned on the carton. GERD is a condition where stomach acid leaks out of the stomach and up into the gullet (oesophagus).

user15594 Oct 30, 2011, 6:40:12 AM

It can be the only active ingredient in heartburn medicines that provide long-lasting relief of symptoms, or it can be found in medicines that provide both short- and longer-term symptom relief. That’s why it is always important to read and follow the Drug Facts label. Talk to a healthcare provider before giving an OTC medicine containing famotidine to a child under the age of 12.

FooF0x Feb 23, 2018, 5:07:45 PM

Your medical doctor will decide to treat you with the medicines or change some of the medicines that will be administered to you. In addition, Geriatric studies have also not been performed to date and geriatric specific problems that would limit the usefulness of the combination of Ibuprofen and famotidine in the elderly. Acebutolol Alacepril Alprenolol Amikacin Amiloride Arotinolol Aspirin Atenolol Azosemide Befunolol Bemetizide Benazepril Bendroflumethiazide Benzthiazide Betaxolol Bevantolol Bisoprolol Bopindolol Bucindolol Bumetanide Bupranolol Buthiazide Canrenoate Captopril Carteolol Carvedilol Cefditoren Pivoxil Cefpodoxime Proxetil Celiprolol Chlorothiazide Chlorthalidone Cilazapril Clopamide Cyclopenthiazide Cyclosporine Delapril Dilevalol Enalapril Enalaprilat Esmolol Ethacrynic Acid Fosinopril Furosemide Hydrochlorothiazide Hydroflumethiazide Imidapril Indapamide Labetalol Landiolol Levobunolol Lisinopril Lithium Mepindolol Methyclothiazide Metipranolol Metolazone Metoprolol Moexipril Nadolol Nebivolol Nipradilol Oxprenolol Penbutolol Pentopril Perindopril Pindolol Piretanide Polythiazide Propranolol Quinapril Ramipril Sotalol Spirapril Spironolactone Talinolol Temocapril Tertatolol Timolol Torsemide Trandolapril Triamterene Trichlormethiazide Xipamide Zofenopril There may be other forms of interactions.

wklhuey Mar 6, 2014, 7:39:56 AM

The upper part of your intestine – known as the duodenum – is more vulnerable to the attack of harsh acids. Owing to this, this layer may encounter rupture or holes in the inner walls. Drugs like pantoprazole as well as famotidine are used for the treatment of gastric problems. As famotidine is available as an OTC drug, its price is more affordable than pantoprazole.

metamas May 4, 2018, 10:57:27 PM

DUEXIS (IBUPROFEN AND FAMOTIDINE) INDICATIONS AND USAGE DUEXIS (ibuprofen and famotidine), a combination of the NSAID ibuprofen and the histamine H-receptor antagonist famotidine, is indicated for the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk of developing upper gastrointestinal ulcers, which in the clinical trials was defined as a gastric and/or duodenal ulcer, in patients who are taking ibuprofen for those indications. The clinical trials primarily enrolled patients less than 65 years of age without a prior history of gastrointestinal ulcer.

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