When other therapies have failed to control tuberculosis, ethionamide is used as a last resort.
Other names for this medication:
Trecator
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Janssen plans to initiate Phase III clinical trials on Sirturo in the first quarter of 2013. Multi-drug resistant tuberculosis (MDR-TB) disease details "Sirturo received accelerated approval from the US Food and Drug Administration (FDA) for the treatment of MDR-TB in December 2012." The culture conversation success after 72 weeks of the study was about 70.1% in Sirturo-administered patients, while in the placebo group it was 56.1%.
Other side effects include paralysis resulting in the inability to breathe. Specifically it is a second line treatment used for active drug resistant tuberculosis. It is not recommended during pregnancy as it may cause kidney or hearing problems in the baby. It was removed from the World Health Organization's List of Essential Medicines in 2019.
Target: Antibacterial Ethionamide is a second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. Expression of the ethA gene is controlled by EthR, a transcriptional repressor.
Follow your doctor's instructions carefully.The dosage is based on your age, weight, medical condition, and response to treatment.Antibiotics work best when the amount of medicine in your body is kept at a constant level. HOW TO USE: Take this medication by mouth with or without food, usually once daily or as directed by your doctor. If this medication causes stomach upset or nausea/vomiting, take this medication with meals.
Retrieved from "https://en.wikipedia.org/w/index.php?title=Enviomycin&oldid=964544212" Categories: Polypeptide antibiotics Antiinfective agent stubs Hidden categories: Drugs with non-standard legal status Articles with changed DrugBank identifier Articles with changed ChemSpider identifier Articles with changed EBI identifier Articles with changed InChI identifier Drugboxes which contain changes to verified fields All stub articles US patent 3892732 ^ Dapsone Acedapsone Diucifon Promin Solasulfone Sulfoxone 4-Aminosalicylic acid (Calcium aminosalicylate Sodium aminosalicylate) Ethylenediamine/arabinosyltransferase inhibitor: Ethambutol SQ109 Hydrazides/mycolic acid synth. inhibition: Isoniazid Methaniazide Thiocarbamides: Ethionamide Prothionamide Thiocarlide Others/unsorted: Thioacetazone (amithiozone) Phenazine (Clofazimine) Pyrazine (Pyrazinamide, Morinamide) Isoxazole (Terizidone) Bedaquiline Nitroimidazole (Delamanid, Pretomanid) Ethambutol/isoniazid Ethambutol/isoniazid/pyrazinamide/rifampicin Ethambutol/isoniazid/rifampicin Isoniazid/pyridoxine/sulfamethoxazole/trimethoprim Rifampicin/isoniazid/pyrazinamide WHO-EM Withdrawn from market Clinical trials: Phase III Never to phase III This antiinfective drug article is a stub.