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ethionamide 250 mg

When other therapies have failed to control tuberculosis, ethionamide is used as a last resort.

Other names for this medication:

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Ask your doctor or pharmacist for more information. A prescribed drug called ethionamide is used to treat tuberculosis. Other prescriptions for this medicine might be given. Bacteria that attack the lungs are what cause tuberculosis, a disease.


The duration of treatment should be based on response to treatment. -Maintenance doses may be administered in divided doses in patients who exhibit poor gastrointestinal tolerance. Patients who adhere to treatment but fail to respond may be at risk ofabsorption syndrome. The American Academy of Pediatrics recommends once a day treatment with isoniazid, rifampin, and pyrazinamide for two months in patients with M tuberculosis, and once a day treatment with isoniazid and rifampin for nine. The duration of treatment should be based on the patient's clinical response. 10 to 20 mg/kg orally in 2 to 3 divided doses per day (after meals) OR 15 mg/kg orally once a day -Maximum dose: 1000 mg/day Comments: -Additional drug/s should be given with this drug to treat patients with susceptible strains of tuberculosis. Detailed information on the Ethionamide. The initial dose regimen is 500 to 1000 IU once a day for 1 to 2 days, then 250 to 1000 IU twice a day for 1 to 2 days, and the dose should be increased to 1000 IU in 3 to 4 divided doses. Drug monitoring should be considered in patients with malabsorption syndrome. Treatment of active Tuberculosis in patients who are resistant to isoniazid or rifampin is possible. Treatment of active Tuberculosis in patients with resistance to isoniazid orrifampin can be done. The usual adult dose is active for Tuberculosis. The usual dose of Tuberculosis is active.

Missed dose

Don't take extra medicine to make up the missed dose. If it's close to your next scheduled dose, skip the missed dose. You should take the missed dose as soon as possible.


Call the Poison Help line if you need emergency medical assistance.

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Side effects

For more details, consult your physician or pharmacist. For medical advice about side effects, contact your doctor. This is not a comprehensive list of ethionamide side effects, but some common ones include: nausea, vomiting, diarrhea, stomach pain, weight loss, increased salivation, and mouth inflammation. Take a look at the "Drug Precautions" section. Ethionamide has been linked to serious side effects. If any side effect bothers you or does not go away, let your doctor know right away. Contact the FDA at 1-800-FDA-1088 to report side effects.


Take with or without food. Taking Ethionamide with food may reduce gastrointestinal upset.

Can ethionamide cause seizures?

Ethionamide side effects confusion; unusual thoughts or behavior; eye pain, blurred vision, double vision; a light-headed feeling, like you might pass out; seizure (convulsions); or.

What is the side effects of ethionamide?

Nausea, vomiting, diarrhea, abdominal/stomach pain, increased saliva, strange metallic taste in the mouth, loss of appetite, or sores in the mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Is ethionamide and ethambutol same?

Myambutol (ethambutol) works well to treat or prevent mycobacterial infections, but has to be combined with other medicines and taken for a long period of time. Trecator (ethionamide) is effective at treating tuberculosis when taken together with other antibacterial drugs.

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LawF0rge52 Jan 19, 2021, 4:29:32 PM

Janssen plans to initiate Phase III clinical trials on Sirturo in the first quarter of 2013. Multi-drug resistant tuberculosis (MDR-TB) disease details "Sirturo received accelerated approval from the US Food and Drug Administration (FDA) for the treatment of MDR-TB in December 2012." The culture conversation success after 72 weeks of the study was about 70.1% in Sirturo-administered patients, while in the placebo group it was 56.1%.

clr Oct 26, 2013, 5:30:16 PM

Other side effects include paralysis resulting in the inability to breathe. Specifically it is a second line treatment used for active drug resistant tuberculosis. It is not recommended during pregnancy as it may cause kidney or hearing problems in the baby. It was removed from the World Health Organization's List of Essential Medicines in 2019.

Slump 64 Jun 1, 2016, 3:59:20 PM

Target: Antibacterial Ethionamide is a second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. Expression of the ethA gene is controlled by EthR, a transcriptional repressor.

mr fackler Jul 22, 2021, 5:39:17 PM

Follow your doctor's instructions carefully.The dosage is based on your age, weight, medical condition, and response to treatment.Antibiotics work best when the amount of medicine in your body is kept at a constant level. HOW TO USE: Take this medication by mouth with or without food, usually once daily or as directed by your doctor. If this medication causes stomach upset or nausea/vomiting, take this medication with meals.

Alan Hortz Sep 19, 2022, 11:52:25 AM

Retrieved from "" Categories: Polypeptide antibiotics Antiinfective agent stubs Hidden categories: Drugs with non-standard legal status Articles with changed DrugBank identifier Articles with changed ChemSpider identifier Articles with changed EBI identifier Articles with changed InChI identifier Drugboxes which contain changes to verified fields All stub articles US patent 3892732 ^ Dapsone Acedapsone Diucifon Promin Solasulfone Sulfoxone 4-Aminosalicylic acid (Calcium aminosalicylate Sodium aminosalicylate) Ethylenediamine/arabinosyltransferase inhibitor: Ethambutol SQ109 Hydrazides/mycolic acid synth. inhibition: Isoniazid Methaniazide Thiocarbamides: Ethionamide Prothionamide Thiocarlide Others/unsorted: Thioacetazone (amithiozone) Phenazine (Clofazimine) Pyrazine (Pyrazinamide, Morinamide) Isoxazole (Terizidone) Bedaquiline Nitroimidazole (Delamanid, Pretomanid) Ethambutol/isoniazid Ethambutol/isoniazid/pyrazinamide/rifampicin Ethambutol/isoniazid/rifampicin Isoniazid/pyridoxine/sulfamethoxazole/trimethoprim Rifampicin/isoniazid/pyrazinamide WHO-EM Withdrawn from market Clinical trials: Phase III Never to phase III This antiinfective drug article is a stub.

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