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Missing doses can make treatment more challenging; avoid doing so. Efavirenz is used in combination with other medications to treat HIV infection.

Other names for this medication:
Stocrin, Symfi, Atripla, Sustiva

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Description

Ask your doctor or pharmacist for more information. Efavirenz is a medication used in conjunction with other medications to help treat HIV infection, which is the virus that causes AIDS (acquired immune deficiency syndrome). Other prescriptions for this medicine might be given.

Dosage

Be sure to carefully follow the instructions on your prescription label. Take this medication exactly as prescribed by your doctor. Weight will be used to determine the child's efavirenz dosage. The dosage your doctor prescribes may depend on the following factors: the condition being treated; other medical conditions you have; other medications you are taking; how you respond to this medication; your weight; your height; your age; and your gender. Efavirenz should be taken orally once daily on an empty stomach, preferably before bed. The recommended daily dose for adults is 600 mg, which can be obtained by taking three 200-mg capsules or one tablet.

Missed dose

Taking two doses at once is not advised. Before you completely run out of medicine, have your prescriptions filled. If it's almost time for your next dose, skip the missed dose and take the medication as soon as you remember.

Overdose

Get immediate medical help or dial 1-800-222-1222 for poison help.

Storage

Store at 25°C.

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Side effects

In the event that you experience: For medical advice about side effects, contact your doctor. The following are examples of frequent side effects: Your immune system is impacted by efavirenz, which could result in some side effects (even weeks or months after taking this medication). Effavirenz side effects (more information) If you experience any of the warning signs of an allergic reaction (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling), seek emergency medical attention. Psychiatric symptoms or nervous system problems may happen even months or years after you have been taking efavirenz. Inform your doctor if you have: There may be additional side effects; this is not a comprehensive list. Call 1-800-FDA-1088 to report side effects to the FDA. a seizure; hallucinations; difficulty concentrating, speaking, or moving (these symptoms may appear months or years after you begin taking efavirenz); nervous system issues such as dizziness, drowsiness, confusion, difficulty concentrating, strange dreams, insomnia, or issues with speech, balance, or muscle movement; serious mental health issues such as anxiety, paranoia, unusual behavior, feeling down or hopeless, hallucinations, or suicidal thoughts; or liver issues such as nausea Changes in the shape or location of body fat, particularly in the arms, legs, face, neck, breasts, and waist, as well as nausea, vomiting, dizziness, drowsiness, trouble concentrating, rash, headache, and fatigue. Fever, sweating at night, swollen glands, cold sores, coughing, wheezing, diarrhea, weight loss, difficulty speaking or swallowing, issues with balance or eye movement, feeling weak or prickley, swelling in your neck or throat (enlarged thyroid), menstrual changes, and impotence are all indicators of a new infection.

Interactions

Controlled trials evaluating the long-term suppression of HIVRNA with efavirenz have not yet produced any results. Efavirenz is recommended for the treatment of HIV-1 infection when used in conjunction with other antiretroviral drugs. This indication is based on analyses of plasma HIV- RNA levels and CD4 cell counts in controlled studies of up to 24 weeks in duration.

Contraindications

Additionally, if you want to get pregnant, consult your doctor. Additionally, efavirenz may enter breast milk and seriously harm the unborn child. Those who take efavirenz shouldn't breastfeed. Never take any additional medications without first consulting your doctor. If you are allergic to efavirenz or any of its inactive ingredients, you should not take it. After treatment is stopped, efavirenz may continue to circulate in your blood for some time. Whether these flaws were brought on by efavirenz is unknown. Herb of St. John (Hypericum perforatum). extended QTc. Rash may be a serious problem in some children. Animal offspring and pregnant women who received efavirenz have both experienced serious birth defects. Efavirenz may have more side effects, such as drowsiness, when combined with alcohol or other medications that have similar side effects. If you are nursing a child, consult your doctor. If you experience any side effects while your child is taking efavirenz, including rash, call your doctor right away. If you are pregnant, tell your doctor as soon as possible. The Centers for Disease Control and Prevention advise against breastfeeding for mothers who have HIV because the virus can be passed from mother to child through the mother's milk. This means that for 12 weeks after stopping efavirenz, you should continue using contraception. These medicines include prescription and nonprescription medicines and herbal products, especially St. Even if they also use other forms of birth control, women still need to use a safe barrier method of contraception, like a condom or diaphragm. While taking efavirenz and for 12 weeks after stopping it, women shouldn't get pregnant. Efavirenz may render hormone-based birth control methods like pills, injections, or implants ineffective, so women shouldn't rely solely on them. You may need to stop breastfeeding or use a different medicine. Your doctor will monitor your risk and mya need to changes to other medications you are taking that may increase your risk for QTc prolongation.

What class of drug is efavirenz?

Efavirenz is in a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It works by decreasing the amount of HIV in the blood.

What is the most common side effect of efavirenz?

The most common side effects of efavirenz are (most common in bold): Rash, itching, abnormal dreams, difficulty concentrating, dizziness, headache, difficulty sleeping, drowsiness, abdominal pain, diarrhoea, nausea, vomiting, tiredness, anxiety, depression, raised triglyceride and liver enzyme levels.

Why efavirenz is taken at night?

Efavirenz is dosed once daily, and is generally administered in the evening owing to its central nervous system side-effects.

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Testimonials
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verdammelt Jul 10, 2013, 2:23:39 PM

15% off subscription plans with promo code:GOOD15GOOD15 another package of Efavirenz STOCRIN from MSD,shallow focus

Leeo97one Nov 5, 2010, 4:20:23 PM

Avoid combination Enzalutamide: May decrease the serum concentration of CYP3A4 Substrates (High risk with Inducers). Monitor therapy Bosutinib: CYP3A4 Inducers (Moderate) may decrease the serum concentration of Bosutinib. Consider therapy modification Bosentan: May decrease the serum concentration of CYP3A4 Substrates (High risk with Inducers).

svart Oct 8, 2015, 4:02:24 PM

Severe depression Suicidal thoughts Aggression Severe depression Extreme fear Hallucinations The following medicines should be avoided, in case doctor recommends you Efavirenz to avoid possible drug interactions. Efavir 600mg (Efavirenz) is a prescription Human Immunodeficiency Virus type 1 (HIV-1) drug, used to treat in adults and in children, who are at least three months old and weigh at least 3.5 kg. The drug is safe and effective in children younger than three months and who weigh less than 3.5 kg. Take the capsule when you are empty stomach, or take it with low-calorie food.

Cristofayre Jan 21, 2020, 6:35:22 AM

Efavirenz does not inhibit the synthesis of mobile DNA polymerases and HIV-2 transcriptase in people. The drug ought to be used in combination with other antiretroviral remedy. also, the time of excretion from the frame will increase with severe liver dysfunctions. Antiviral effect of Sustiva (conventional) is due to the potential of efavirenz to selectively inhibit HIV-1 opposite transcriptase. The each day component dictates the finest fixation and an possibility to achieve it.

demalexx Nov 7, 2019, 5:14:10 PM

People who receive this medicine may continue to have some of the problems usually related to AIDS or HIV disease. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. It will not keep you from spreading HIV to other people. This may help delay the development of problems that usually result from AIDS or HIV disease. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system.

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