Side effects
It is safe to take digoxin during pregnancy. Anorexia, nausea, vomiting, diarrhea, abdominal pain, visual disturbance, headache, fatigue, drowsiness, confusion, delirium, hallucinations, depression, arrhythmia, heart block, intestinal ischaemia, gynecomastia on long-term use, and thrombocytopenia have all been reported as side effects of excessive dosage.
Interactions
Ask your doctor or pharmacist for more information. Tell your doctor right away if you take any of the following medications: antacids like Tums, Citrical, or Maalox, verapamil (Calan), amiodarone (Cordarone), propafenone (Rythmol), indomethacin (Indocin), itraconazole (Sporanox), alprazolam (Xanax), spironolactone (Aldactone), diphenoxy Inform your doctor about all of the medications you take, including any prescription and over-the-counter drugs, vitamins, and herbal supplements.
Contraindications
Digoxin can cause dizziness or blurred vision. Do not drive or operate heavy machinery until you know how digoxin affects you. If you have a condition known as ventricular fibrillation or are allergic to digoxin or digitoxin, you should avoid taking digoxin. Digoxin has been linked to a number of serious side effects, including AV (atrioventricular) block, which should be reported as soon as possible if you experience any of the following symptoms: dizziness, confusion, or a pounding in the chest. Wolff-Parkinson-White Syndrome, which is characterized by an abnormal electrical pathway in the heart, should also be reported as soon as possible.
It is generally believed that the amount of digoxin in breast milk that a breast-fed infant would receive is not likely to affect the infant. Your child’s doctor will want to closely monitor the effectiveness of this medication for your child. Pregnancy: Digoxin should be taken by pregnant women only if clearly needed. Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Moreover, it may be used to convert paroxysmal supraventricular tachycardia to sinus rhythm. READ THIS NEXT: Soursop vs Cherimoya – Nutrition Facts It reaches about 5 feet tall, with many large, thick, hairy leaves at the base and tube-shaped, spotted, purple flowers.
Serum digoxin concentrations should be monitored prior to initiation of Tykerb and throughout coadministration. This increase in paclitaxel exposure may have been underestimated from the in vivo evaluation due to study design limitations. Digoxin: Following coadministration of Tykerb and digoxin (P-gp substrate), systemic AUC of an oral digoxin dose increased approximately 2.8-fold. Dose adjustment of lapatinib should be considered for patients who must receive concomitant strong inhibitors or concomitant strong inducers of CYP3A4 enzymes. Ketoconazole: In healthy subjects receiving ketoconazole, a CYP3A4 inhibitor, at 200 mg twice daily for 7 days, systemic exposure (AUC) to lapatinib was increased to approximately 3.6-fold of control and half-life increased to 1.7-fold of control.
The usual daily Lanoxin dose is 125 to 250 micrograms (0.125 to 0.25 mg) for patients with normal renal function. More Medicine Information : Fortum (Ceftazidime) Injection Uses, Dose Administration, Side Effects Unless doses lower than those in non elderly patients used.
Some of the common side effects of Digoxin include nausea, diarrhea, feeling weak or disoriented, headache, weakness, anxiety, depression, or rash. However, if you see any of the following symptoms of a Digoxin allergy, get emergency medical attention: hives, breathing trouble, swelling of the cheeks, tongue, lips, or throat. If you experience a rapid, slow, or irregular heart rate; bloody or black, tarry stools; disorientation, weakness, hallucinations, strange thoughts or behavior; breast enlargement or soreness; hazy or yellowed eyesight, call your doctor at once.
Oral Contraceptive (estrogen/progesterone): Coadministration of Latuda (40 mg/day) at steady state with an oral contraceptive (OC) containing ethinyl estradiol and norelgestimate resulted in equivalent AUC and Cmax of ethinyl estradiol and norelgestromin relative to OC administration alone. Given the primary CNS effects of Latuda, caution should be used when it is taken in combination with other centrally acting drugs and alcohol. This suggests that an interaction of Latuda with drugs that are inhibitors or inducers of these enzymes is unlikely. Digoxin dose adjustment is not required when coadministered with Latuda.
Suggested doses are intended only as an initial guide. The maintenance dosage should be based upon the percentage of the peak body stores lost each day through elimination. The possibility of reduced renal function and lower lean body mass should be taken into account when dealing with elderly patients. Children over ten years of age require adult dosages in proportion to their body weight.