Call your doctor at once if you have: For medical guidance on side effects, contact your doctor. Typical adverse reactions to Sinemet include: If you experience hives, breathing difficulties, swelling of your face, lips, tongue, or throat, you should seek emergency medical attention. Sinemet side effects (more information) While working, conversing, eating, or driving during the day, some Sinemet users have fallen asleep. If this happens, consult your physician. If you experience any issues with daytime sleepiness or drowsiness, let your doctor know. There may be other side effects; this is not a comprehensive list. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets. While taking this medication, you might experience stronger urges to gamble or engage in increased sexual activity. You may have noticed that the color of your saliva, urine, or sweat is dark, such as red, brown, or black. You may report side effects to FDA at 1-800-FDA-1088. jerky or twisting muscle movements; headache, dizziness; low blood pressure (feeling light-headed); sleep problems, strange dreams; dry mouth; muscle contractions; or nausea, vomiting, constipation. Uncontrolled facial movements like chewing, lip smacking, frowning, tongue movement, blinking, or eye movement; worsening tremors (uncontrolled shaking); persistent or severe vomiting or diarrhea; confusion, hallucinations, unusual changes in mood or behavior; depression or suicidal thoughts; or severe nervous system reactions like rigid muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, or feeling like you might faint.
To learn more, consult your physician or pharmacist. Tell your doctor right away if you take any of the following: antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and Inform your physician of all the drugs you take, including vitamins, herbal supplements, prescription and non-prescription medications.
Before you know how Sinemet affects you, avoid operating heavy machinery or driving. If you are taking, or have recently stopped taking, a monoamine oxidase inhibitor (MAOI), you should not take Sinemet. Serious side effects have been reported with Sinemet. unusual or uncontrolled movements of the mouth, tongue, face, head, neck, arms, and legs fast, irregular, or pounding heartbeat depression thoughts of death or suicide hallucinations swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs hoarseness difficulty swallowing or breathing hives black, tarry stools red blood in stools blood in vomit vomit that looks like coffee grounds Sinemet can cause drowsiness, dizziness, and blurred vision.