Call your doctor at once if you have: For medical guidance on side effects, call your doctor. Combigan side effects (more detail) Typical adverse reactions to Combigan include: If you experience any of these symptoms of an allergic reaction to Combigan, seek immediate medical attention: hives; trouble breathing; swelling of your face, lips, tongue, or throat. There may be other side effects; this is not a comprehensive list. Call 1-800-FDA-1088 to contact FDA and report side effects. use of the eye drops may cause mild stinging, burning, or drowsiness, as well as a mild itching, redness, or irritation of the eyes. Slow or irregular heartbeats, rapid heartbeats or fluttering in the chest, shallow breathing that makes you feel like you might pass out, intense swelling, redness, or discomfort in or around the eye, eye pain or increased watering, or numbness or tingling in the hands or feet are all symptoms to watch out for.
Before combining Combigan with a sedative, narcotic pain reliever, muscle relaxant, or medication for anxiety, depression, or seizures, consult your doctor. Combigan drug interactions (more detail) More information on Combigan (brimonidine / timolol ophthalmic) Price & coupons Generic availability In Spanish FDA approval history Patient resources Advanced Reading Professional resources Prescribing Information Related treatment guides Glaucoma/Intraocular Hypertension Glaucoma Glaucoma/Intraocular Hypertension In this medication guide, not all potential interactions are covered. Combigan may interact with other medications, including over-the-counter drugs, prescription drugs, vitamins, and herbal remedies. Combigan Product Label References Tell your doctor about all of your current medications, as well as any that you start using or stop using while taking Combigan, in particular: This is not a comprehensive list. These effects may be exacerbated if this medication is taken with other medications that cause drowsiness or slow breathing. Digoxin, digitalis, reserpine, antidepressants such as amitriptyline, bupropion, clomipramine, desipramine, doxepin, duloxetine, fluoxetine, imipramine, nortriptyline, and paroxetine, MAO inhibitors such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylc
Although Combigan had minimal effect on the blood pressure of most patients in clinical studies, caution should be exercised in treating patients with severe cardiovascular disease. Combigan contains benzalkonium chloride which may be absorbed by soft contact lenses. Combigan may worsen diseases associated with weak blood flow. Patients who have Raynaud's phenomenon, orthostatic hypotension, cerebral or coronary insufficiency, or both, should use Combigan with caution. If you experience any of the following symptoms, contact your doctor right away and stop taking Combigan: sudden difficulty breathing, sudden extreme fatigue, swelling of the extremities, or low blood pressure during surgery. Until you know how Combigan affects you, avoid operating heavy machinery or driving. You should not use Combigan if you have any of the following conditions: severe chronic obstructive pulmonary disease, sinus bradycardia, second- or third-degree atrioventricular block, heart failure, or a history of bronchial asthma. Eye infections. Eyedrop containers can become inadvertently contaminated by patients who not use eye drops properly or do not store them in a clean area. Consult your doctor about how to correctly recognize symptoms of low blood pressure while taking Combigan if you have diabetes and take insulin or other medications to control your blood sugar. If you have hyperthyroidism, talk to your doctor about the best way to recognize thyroid emergency symptoms while taking Combigan. concealing the hyperthyroidism symptoms. concealment of low blood sugar symptoms. Combigan can make you feel drowsy, sleepy, and dizzy due to muscle weakness. 15 minutes after administering Combigan, replace your contact lenses. Before taking Combigan, take out your contact lenses. Combigan is known to cause serious side effects, such as the following: worsening of conditions involving poor blood flow. severe cardiac reactions, such as heart failure. severe asthmatic patients' bronchospasms and other respiratory reactions. If you have trouble breathing, stop taking Combigan and notify your doctor right away. There have been reports of bacterial eye infections associated with the use of eye drop products. heart disease getting worse. In order to avoid complications during major surgery, your doctor may advise stopping Combigan.