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celecoxib teva 100mg

Children 2 years of age and older who have juvenile rheumatoid arthritis, a type of arthritis that affects children, can also be treated with celecoxib. Additionally, celecoxib is used to treat painful menstrual cycles as well as short-term pain from injuries, surgeries, other medical or dental procedures, or temporary medical conditions. The NSAID COX-2 inhibitors include celecoxib in their class of medications. Celecoxib is used to treat osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, three types of arthritis that primarily affect the spine and are characterized by pain, tenderness, swelling, and stiffness. Osteoarthritis is characterized by a breakdown of the lining of the joints. It works by stopping the body's production of a substance that causes pain and inflammation.

Other names for this medication:
Celebrex, Elyxyb, Seglentis, Consensi

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Decadron, Sumatriptan, Cobix, Meloxicam, Rizatriptan, Naprelan, Probenecid, Phenazopyridine, Mobic, Ibuprofen, Amitriptyline, Paracetamol


As mentioned in the pharmacodynamics section of this drug entry, celecoxib may cause an increased risk of thrombotic events. Non-steroidal anti-inflammatory drugs (NSAIDs) damage the mucosa of the gastrointestinal tract, lead to ulceration, and exacerbate existing ulcers by inhibiting the synthesis of prostaglandins. Inflammatory mediators induce the expression of COX-2, which is highly expressed in inflamed tissues. Celecoxib has been found to inhibit carbonic anhydrase enzymes 2 and 3, further enhancing its anticancer effects., Celecoxib binds to the cadherin-11 (CDH11) protein, which is thought to be involved in the progression of tumors., Due to its diminished impact on gastric mucosal prostaglandin synthesis when compared to placebo, celecoxib poses a lower risk of ulceration than other NSAIDS. Inhibiting these mediators as a result reduces inflammation and pain. Thrombboxane (TXA2), prostacyclin (PGI2), prostaglandin E2 (PGE2), prostaglandin D2 (PGD2), and prostaglandin F2 (PGF2) are among the metabolites whose synthesis is decreased when this enzyme is inhibited. The vasoconstrictive effects of thromboxane A2 cause increased platelet aggregation, which is uncontrolled when the actions of prostacyclin, a platelet aggregation inhibitor, are suppressed by the inhibition of COX-2. This increases the risk of thrombosis that results from COX-2 inhibition. Celecoxib is a selective noncompetitive inhibitor of the COX-2 enzyme, in contrast to the majority of NSAIDs, which inhibit both COX-1 and COX-2 cyclooxygenases.


Ask your doctor or pharmacist if you are not sure if you need to take your medication with food. Celecoxib capsules are usually taken once or twice a day. Celecoxib is available as a capsule to be swallowed. Celecoxib is also sometimes used with surgery and other treatments to reduce the number of polyps (abnormal growths) in the colon (large intestine) and rectum in patients with familial adenomatous polyposis (a condition in which hundreds or thousands of polyps form in the colon and cancer may develop). Do not take more or less of it or take it more often than prescribed by your doctor. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. If you're taking more than 200 mg of celecoxib at once, you should eat before taking the medication. If you are taking up to 200 mg of celecoxib capsules at a time, you may take the medication with or without food. When administering this medication to a child or if you are unable to swallow the capsules, you can open the capsules and sprinkle the contents over a teaspoon of cold or room temperature applesauce. Celecoxib should only be taken as prescribed. Discuss the dangers of using this medication for your condition with your doctor. Then drink water to wash down the mixture and be sure that you have swallowed all of it. Ask your doctor or pharmacist for more details if you believe this medication may be prescribed for another purpose. To help you remember to take celecoxib capsules, take it around the same time(s) every day. Continue eating normally unless your doctor instructs you otherwise. When it is time to take your medication, inhale the entire mixture. You may prepare the mixture in advance and store it for up to 6 hours in a refrigerator.

Missed dose

If you miss a dose, don't take a second one to make up for it. If, however, it is almost time for the subsequent dose, skip the missed one and carry on with your regular dosing schedule. Take the missed dose of celecoxib as soon as you remember if you are taking it.


Call 1-800-222-1222 for poison help if you need immediate medical attention.


Avoid light and moisture, and maintain a temperature below 30°C. Keep out of the reach of children.

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Side effects

If you experience any unusual issues while taking this medication, contact your doctor right away. Celecoxib could have negative effects. Prior to speaking with your doctor, stop using celecoxib if you experience any of the following symptoms: gas, bloating, sore throat, cold symptoms, constipation, dizziness, dysgeusia, unexplained weight gain, swelling of the abdomen, feet, ankles, or lower legs, diarrhea, nausea, excessive tiredness, unusual bleeding or bruising, itching, lack of energy, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin You or your doctor can submit a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online at or by phone at 1-800-332-1088 if you experience a serious side effect. Any of the following symptoms, as well as those listed in the IMPORTANT WARNING section, should be reported to your doctor right away. Tell your doctor if any of these symptoms are severe or do not go away: gas or bloating sore throat cold symptoms constipation dizziness dysgeusia unexplained weight gain shortness of breath or difficulty breathing swelling of the abdomen, feet, ankles, or lower legs diarrhea nausea excessive tiredness unusual bleeding or bruising itching lack of energy loss of appetite pain in the upper right part of the stomach yellowing of the skin or eyes flu-like symptoms blisters fever rash hives swelling of the face, throat, tongue, lips, eyes, or hands hoarseness difficulty swallowing or breathing pale skin fast heartbeat cloudy, discolored, or bloody urine back pain difficult or painful urination frequent urination, especially at night Some side effects can be serious.


If you take an antidepressant, steroid medication, or medication to treat or prevent blood clots, consult your doctor before using celecoxib. Drug interactions with celecoxib (more information) Many drugs can interact with celecoxib. Reviews (239) Patient tips Drug images Compare alternatives Pricing & coupons En espaol Drug class: cox-2 inhibitors Patient resources Advanced Reading Other brands Celebrex, Elyxyb Professional resources Prescribing Information Related treatment guides Ankylosing Spondylitis Fibromatosis Juvenile Rheumatoid Arthritis Familial Adenomatous Polyposis Not all potential interactions are covered in this list. Taking certain medicines with an NSAID may increase your risk of a stomach ulcer or bleeding. In addition to any new or discontinued medications, make sure your doctor is aware of all of your current medications. This covers vitamins, herbal products, prescription and over-the-counter medications, and other drugs as well.


Tell your doctor and pharmacist about all prescription and over-the-counter medicines, vitamins, dietary supplements, and herbal products you are currently taking or intend to take. Aspirin, other NSAIDs like ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), sulfa drugs, other medications, or any of the inactive ingredients in celecoxib capsules should all be avoided if you are allergic to celecoxib.

What is the major side effect of celecoxib?

Tell your doctor right away if you have any serious side effects, including: severe headache, pain/swelling/warmth in the groin/calf, signs of kidney problems (such as change in the amount of urine), difficult/painful swallowing, symptoms of heart failure (such as swelling ankles/feet, unusual tiredness, unusual/sudden ...

What is celecoxib made from?

Celecoxib is hydrophobic (log P is 3.5) and is practically insoluble in aqueous media at physiological pH range. The inactive ingredients in CELEBREX include: croscarmellose sodium, edible inks, gelatin, lactose monohydrate, magnesium stearate, povidone and sodium lauryl sulfate.

What pain reliever can I take with celecoxib?

Celecoxib with other painkillers It's fine to take paracetamol with celecoxib. You can also take opioid-type painkillers such as codeine, co-codamol, tramadol or morphine in combination with celecoxib. other related anti-inflammatory painkillers (NSAIDs) like ibuprofen or naproxen.

Is celecoxib brand or generic?

Celebrex is available as a generic drug called celecoxib. A generic drug is an exact copy of the active drug in a brand-name medication.

What classification is celecoxib?

Celebrex belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).

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Anvi Feb 4, 2013, 4:29:51 PM

There have been a limited number of case reports of maternal NSAID use and neonatal renal dysfunction without oligohydramnios, some of which were irreversible. In rats, exposure to celecoxib during early embryonic development resulted in pre-implantation and post-implantation losses at oral doses ≥50 mg/kg/day (approximately 6 times human exposure based on the AUC 0-24 at 200 mg twice daily for RA). Premature Closure of Fetal Ductus Arteriosus Avoid use of NSAIDs, including celecoxib, in pregnant women at about 30 weeks gestation and later. These adverse outcomes are seen, on average, after days to weeks of treatment, although oligohydramnios has been infrequently reported as soon as 48 hours after NSAID initiation. If NSAID treatment is necessary between about 20 weeks and 30 weeks gestation, limit celecoxib use to the lowest effective dose and shortest duration possible.

Baltar Nov 13, 2019, 3:29:07 PM

You can purchase Celebrex here at a reasonable cost however we likewise offer our clients extraordinary limits and deals. On the off chance that the customer needs to find a solution to his inquiry, he can contact the specialist on the web. Older individuals and patients after a coronary episode or stroke ought to be cautious with taking this medicine. The most extreme measurement, for this situation, will be 600 mg for every day. In the event that the patient has an affectability to specific components in the structure of this medication, at that point taking additionally would be precluded.

SIDHEEQ PATHATH Mar 6, 2016, 11:19:45 PM

There are no adequate and well-controlled studies of celecoxib in pregnant women. A dose-dependent increase in diaphragmatic hernias was observed when rats were given celecoxib at oral doses ≥30 mg/kg/day (approximately 6 times human exposure based on the AUC0-24 at 200 mg twice daily for RA) throughout organogenesis. Based on animal data, prostaglandins have been shown to have an important role in endometrial vascular permeability, blastocyst implantation, and decidualization. Risk Summary Use of NSAIDs, including celecoxib, during the third trimester of pregnancy increases the risk of premature closure of the fetal ductus arteriosus.

Alamar Oct 6, 2013, 4:02:38 PM

Contact us to get Celecoxib price if want to order it online. Celecoxib, raw material of NASIDs medicine for the treatment of pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.

user18521 Apr 26, 2012, 12:09:59 AM

In the event that an individual has not gotten the vital help, the specialist may allow a measurement increment of up to 400 mg. Be that as it may, the interim between portions of Celebrex ought to be around 5 hours. However, the quality, structure, dynamic component continue as before. That is, such prescription is a non-steroidal mitigating drug.

Remi Thomas Aug 3, 2010, 3:43:45 PM

Experience with celecoxib in patients with mild or moderate renal impairment is limited, therefore such patients should be treated with caution. The maximum recommended daily dose is 400 mg for all indications. As in younger adults, 200 mg per day should be used initially. In the absence of an increase in therapeutic benefit after two weeks, other therapeutic options should be considered. The dose may, if needed, later be increased to 200 mg twice daily.

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