Side effects
Postural hypotension, headache, dizziness, fatigue, gastrointestinal disturbances, bradycardia; rarely decreased peripheral circulation, peripheral oedema, and painful extremities; dry mouth, dry eyes, eye irritation or disturbed vision; impotence; disturbances of urination; influenza-like symptoms; very rarely angina; exacerbation of intermittent claudication or Raynaud's phenomenon; nasal stuffiness; and wheezing.
Interactions
Ask your doctor or pharmacist for more information. Tell your doctor right away if you use beta blockers like metoprolol (Toprol XL, Lopressor), bisoprolol (Zebeta), betaxolol (Kerlone), nebivolol (Bystolic), propranolol (Inderal), digoxin (Lanoxin), verapamil (Calan, Isoptin, Covera, Verelan), diltia In addition to vitamins and herbal supplements, make sure your doctor is aware of all the medications you are taking, both prescription and over-the-counter.
Contraindications
Tell your doctor if you are currently breastfeeding, plan to become pregnant, or have ever experienced a severe allergic reaction to food or any other substance. You should be aware that carvedilol may cause dizziness, lightheadedness, and fainting, especially when you get up too quickly from a lying position. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, herbal products, and nutritional supplements you are taking or plan to take. Do not consume alcoholic beverages or take any prescription or over-the-counter medications that contain alcohol for 2 hours prior to and 2 hours following the administration of carvedilol extended-release capsules. Be sure to mention any of the following: cimetidine; clonidine (Catapres, Kapvay, in Clorpres), cyclosporine (Gengraf, Neoral, Sandimmune); digoxin ( Lanoxin); diltiazem (Cardizem, Cartia, Dilacor, Taztia, Tiazac); epinephrine (Epipen); fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax); insulin; oral medications for diabetes; monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and selegiline (Eldepryl, Emsam, Zelapar); paroxetine (Brisdelle, Paxil); propafenone (Rythmol); quinidine; reserpine; rifampin (Rifadin, Rimactane, in Rifater, in Rifamate); and verapamil (Calan, Covera-HS, Verelan, in Tarka). Before taking carvedilol, tell your doctor and pharmacist if you have are allergic to carvedilol, any other medications, or any of the ingredients in carvedilol tablets and extended- release capsules. Until you are certain of how this medication will affect you, avoid operating machinery or driving a car. You should know that this medication may cause you to feel tired, dizzy, or lightheaded, especially when you first start taking carvedilol and when your dose is increased. If you become pregnant while taking carvedilol, call your doctor. If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking carvedilol. If this becomes an issue, let your doctor know. When you first begin taking carvedilol, this is more typical. If you wear contact lenses, your eyes may become dry during your treatment with carvedilol. To avoid this issue, get out of bed gradually, resting your feet on the floor for a few minutes before standing up. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had asthma or other breathing problems, a slow or irregular heartbeat, or liver disease. Tell your doctor if you have or have ever had issues with blood flow in your feet or legs, diabetes or any other condition that results in low blood sugar, hyperthyroidism (condition in which there is too much thyroid hormone in the body), low blood pressure, Prinzmetal's angina (chest pain that comes at rest with no apparent cause), or pheochromocytoma (a tumor that develops on a gland close to the kidneys and may cause kidney failure).
Carvedilol taken with calcium channel blockers (CCBs) such as diltiazem (Cardizem) or verapamil (Calan) may trigger an irregular heart rhythm or an increase in blood pressure. Carvedilol may increase cyclosporin (Sandimmune, Neoral) blood levels. Therefore, patients with diabetes taking medications that lower blood sugar such as insulin or oral anti-diabetic medications may need to monitor their blood sugar more often.
Pharmacology, part 6: Cardiovascular Medications - Hypertension & Angina Calcium channel blockers (verapamil, nifedipine, diltiazem); centrally-acting alpha-2 agonists (clonidine); beta-1 blockers (metoprolol, atenolol); and nonselective beta blockers (propranolol, labetalol, and carvedilol).
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It is essential to take it regardless of whether you feel great or if your circulatory strain is controlled. Bringing down circulatory strain additionally forestalls future respiratory failures and stroke. Carvedilol 25mg Tablet ought to be taken with food.