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Includes sildenafil side effects, interactions and indications. Sildenafil is used to treat erectile dysfunction and pulmonary arterial hypertension.

Other names for this medication:
Revatio, Viagra, Vizarsin

Similar Products:
Vilitra, Prilox, Lidocaine, Prilocaine, Dapoxetine, Vardenafil

Description

Sildenafil is currently offered generically and, in some countries, even as an over-the-counter drug without a prescription, despite the fact that Pfizer's brand name Viagra has historically been the drug's most well-known name. By inhibiting the cGMP-specific phosphodiesterase type 5 (PDE5), sildenafil ultimately prevents or reduces the breakdown of cyclic guanosine monophosphate (cGMP). It's interesting to note that sildenafil was initially investigated as a possible treatment for angina, or chest pain brought on by insufficient blood flow to the heart, before being accidentally recommended for the treatment of erectile dysfunction in the late 1980s. Nevertheless, it is because of this mechanism that sildenafil is also prescribed to treat pulmonary arterial hypertension. However, it is also well known for interfering with other anti-anginal or anti-hypertensive medications, leading to the development of hypotensive crises that could be sudden, severe, and/or fatal. Nevertheless, sildenafil, among a number of other comparable or related PDE5 inhibitors, has emerged as a popular and efficient treatment for erectile dysfunction, and since it was officially approved for use in the public health in 1998, millions of prescriptions for it have been written globally. This results in increased blood flow into the spongy erectile tissue of the penis, allowing it to grow in size, become erect and rigid, and cGMP present in both the penis and pulmonary vasculature to elicit smooth muscle relaxation and vasodilation.

Dosage

Take this medication only as directed and never increase the dosage. Consult your doctor or pharmacist if you have any questions. Prior to starting to take sildenafil and each time you get a refill, read the Patient Information Leaflet that was given to you by your pharmacist. Take this medication regularly to get the most benefit from it. If your condition does not get better or worsens, let your doctor know. Take it at the same times every day to help yourself remember. Take this medication by mouth as prescribed by your physician to treat high blood pressure in the lungs. You should typically take it three times daily, spaced 4-6 hours apart, with or without food.

Missed dose

To catch up, do not double the dose. Skip the missed dose if it is almost time for the next dose. Take the missed dose as soon as you remember if you forget. When the time comes, take your next dose.

Overdose

Canadian citizens can dial a regional poison control center. Consult your pharmacist or local waste disposal company. Do not increase the dose to make up lost time. Unless specifically instructed to do so, avoid flushing medications down the toilet or pouring them into drains. Do not give anyone else this medication. Store away from bathrooms. You should skip the missed dose if it is almost time for your next dose. Call 911 if a person has overdosed and is exhibiting severe symptoms like fainting or breathing difficulties. If you forget to take a dose, do so right away. Away from children and pets, keep all medications. Periodically, medical exams (like blood pressure checks and eye exams) may be carried out to track your progress or look for any negative effects. In any other case, immediately dial a poison control number. When the product has run its course or is no longer required, dispose of it properly. Away from light and moisture, keep items at room temperature. Symptoms of overdose may include severe dizziness, fainting, painful/prolonged erection. At the scheduled time, take your next dose. Call 1-800-222-1222 to reach your local poison control center if you're a US citizen.

Storage

After 60 days, get rid of any unused suspension. You should not, however, dispose of this medication in the toilet. A medicine take-back program is the preferable method for getting rid of your medication. As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Keep this medication tightly closed in its original container away from the reach of children. If you do not have access to a take-back program, visit the FDA's Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for more information. Do not freeze the suspension; instead, keep it at room temperature or in a refrigerator. Keep the tablets at room temperature, away from sources of extreme heat, and dry (not in the bathroom). To find out about take-back programs in your area, speak with your pharmacist or the garbage/recycling department in your city. Always lock safety caps and immediately store medications up and away and out of young children's sight and reach. http://www.upandaway.org Unused medications should be disposed of in special ways to ensure that pets, children, and other people cannot ingest them.

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Side effects

If you experience any unusual issues while taking this medication, call your doctor right away. Sildenafil and related drugs like tadalafil (Cialis) and vardenafil (Levitra) should not be taken again until you have spoken to your doctor. Do not stop taking sildenafil (Revatio), if you are taking it for PAH, until you have spoken to your doctor. Do not take any additional doses of sildenafil (Viagra) or comparable drugs like tadalafil (Cialis) or vardenafil (Levitra) until you have spoken with your doctor if you are taking sildenafil (Viagra) for erectile dysfunction. The Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program is available online at http://www.fda.gov/Safety/MedWatch or by phone at 1-800-332-1088 if you or your doctor notice a serious side effect. While taking sildenafil, call your doctor right away if you experience a sudden loss of hearing, sometimes accompanied by ringing in the ears or dizziness. While taking sildenafil, call your doctor right away if you suddenly lose your vision. Call your doctor right away if you experience any of the following symptoms: headache, heartburn, diarrhea, flushing (warmth sensation), nosebleeds, trouble falling or staying asleep, numbness, burning, or tingling in the arms, hands, feet, or legs, muscle aches, changes in color vision (seeing a blue tint on objects or having trouble differentiating between blue and green), sensitivity to light, and sudden, severe loss of vision (more details below). Whether the medication was the cause of the hearing loss is unknown. If the medication contributed to the vision loss, it is unknown. Talk to your doctor about the dangers of taking sildenafil. It is unknown whether these events were brought on by heart disease, sildenafil, sexual activity, or a combination of these causes. The majority of these individuals—but not all—had heart issues prior to taking sildenafil. Other negative side effects of sildenafil are possible. Sildenafil may cause side effects. Following the use of sildenafil or drugs that are similar to sildenafil, some patients reported a sudden decline in hearing or loss of hearing. The following symptoms should be reported to your doctor if they are severe or persistent: headache, heartburn, diarrhea, flushing (warmth sensation), nosebleeds, trouble falling or staying asleep, numbness, burning, or tingling in the arms, hands, feet, or legs, muscle aches, changes in color vision (seeing a blue tint to objects or having trouble differentiating between blue and green), sensitivity to light, sudden severe loss of vision (see below for more information), blurriness, and Typically, there was only one ear affected, and stopping the medication did not always help. In some cases, the vision loss was permanent. Men who took sildenafil for erectile dysfunction have experienced sudden deaths, heart attacks, strokes, irregular heartbeats, bleeding in the brain or lungs, high blood pressure, and high blood pressure.

Interactions

For high blood pressure or prostate issues, doctors occasionally prescribe alpha blockers. Chest, jaw, or arm pain are all possible symptoms of angina, which is a form of heart disease. To learn more, consult your physician or pharmacist. If you're unsure whether any of your medications contain nitrates, consult a doctor, pharmacist, or other healthcare professional. Tell your doctor specifically if you take any of the following medications: alpha blockers. Other drugs to treat high blood pressure (hypertension) drugs that block a protein in the body (CYPA4) like some macrolide antibiotics (clarithromycin, telithromycin), some HIV protease inhibitors (indinavir, nelfinavir, ritonavir, saquinavir), some HCV protease inhibitors (boceprevir, telaprevir), and some azole antifungals (ketocon Nitroglycerin, a medication classified as a nitrate, is available as tablets, sprays, ointments, pastes, and patches. Nitrates are commonly used to treat angina. Nitrates can also be found in other medications like isosorbide dinitrate and isosorbide mononitrate. Additionally, nitrates like butyl nitrite and amyl nitrite are present in some "poppers," which are commonly used recreationally. In addition to vitamins and herbal supplements, make sure your doctor is aware of all the medications you are taking, both prescription and over-the-counter. These include Hytrin (terazosin HCl), Flomax (tamsulosin HCl), Cardura (doxazosin mesylate), Minipress (prazosin HCl), or Uroxatral (alfuzosin HCl). The list of medications that can interact with sildenafil is not exhaustive.

Contraindications

You may feel more lightheaded after consuming alcohol or cannabis. Inform your surgeon or dentist about all the products you use, including prescription, over-the-counter, and herbal medications. Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before taking this medication, consult your doctor or pharmacist about your medical history, especially of: heart issues (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure), stroke in the past 6 months, high or low blood pressure, dehydration, penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease), history of painful/prolonged erection (priapism), conditions that may increase the risk Consult your doctor before breast-feeding. Until you can do something safely, avoid driving, operating machinery, or performing any other tasks that call for alertness or sharp vision. Sildenafil should only be used during pregnancy if absolutely necessary. You should discuss the advantages and disadvantages of using sildenafil with your doctor if you intend to become pregnant, are already pregnant, or suspect that you may be pregnant. Limit your alcohol consumption. Do not stop taking this medication unless your doctor instructs you to do so because high blood pressure in the lungs is a dangerous condition that can harm both a pregnant woman and her unborn child. Talk to your doctor if you are using marijuana (cannabis). For more information, speak to your pharmacist. This drug may make you dizzy or cause vision problems. There is a very slight amount of medication in breast milk. Inactive ingredients in this product have the potential to cause allergic reactions or other issues.

How long do sildenafil take to work?

This medicine usually begins to work for erectile dysfunction within 30 minutes after taking it. It continues to work for up to 4 hours, although its action is usually less after 2 hours. Use only the brand of this medicine that your doctor prescribed.

Is sildenafil tablets safe?

Effectiveness and safety The Food and Drug Administration (FDA) considers generics to be just as safe and effective as the original drug. This means that generic sildenafil is just as effective in treating ED as Viagra is when it's used at the same doses as Viagra is used.

How long does sildenafil citrate take to work?

This medicine usually begins to work for erectile dysfunction within 30 minutes after taking it. It continues to work for up to 4 hours, although its action is usually less after 2 hours. Use only the brand of this medicine that your doctor prescribed.

Is sildenafil citrate as good as Viagra?

The takeaway Generic Viagra, or sildenafil citrate, works the same as Viagra, but at a lower cost. While Pfizer still manufactures the “little blue pill,” other companies, globally and in the United States, make sildenafil. It may look different, but it's still an effective treatment for ED.7 days ago

What does sildenafil do to your body?

Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.

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