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buspirone hcl 10mg

Anxiety symptoms like fear, tension, irritability, and dizziness are treated with buspirone. Find out about the indications, interactions, and side effects.

Other names for this medication:

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In healthy volunteers, buspirone was not shown to affect psychomotor or cognitive function, and the risk of developing sedation is relatively low when compared to other anxiolytics, like benzodiazepines. Buspirone showed limited clinical effectiveness for panic disorders, severe anxiety, phobias, and obsessive compulsive disorders, despite being clinically effective for generalized anxiety. However, long-term use of buspirone for more than 3 to 4 weeks has not been shown to be clinically effective in controlled trials, although there were no significant adverse events noted in patients receiving the drug for a year in a study of long-term use. It typically takes 2 to 4 weeks for buspirone to begin having a clinically significant impact on the symptoms of generalized anxiety disorders. Buspirone's delayed onset of action raises the possibility that its therapeutic efficacy in treating generalized anxiety may involve factors other than its molecular mechanism of action at 5-HT1A receptors, or that buspirone may cause 5-HT1A receptor adaptations. Buspirone does not have any anticonvulsant or muscle-relaxing effects, which is due to its lack of effects on GABA receptors. However, because of its inhibitory effect on the aactivity of noradrenergic locus coerulus neurons, it may interfere with arousal reactions. Unlike benzodiazepines and barbiturates used in anxiety disorders, buspirone is not associated with a risk for developing physical dependence or withdrawal, or any significant interaction with central nervous system depressants such as ethanol.


Grapefruit juice should not be consumed in large quantities while taking buspirone. Buspirone is available as a tablet that must be swallowed. Never take it in quantities or frequencies other than those recommended by your doctor. Ask your doctor or pharmacist to explain any instructions on your prescription label that you do not understand, and carefully follow them. It may take several weeks before you reach a dose that works for you. It must be taken consistently, either always with food or always without food each time, and is typically taken twice daily. Follow the buspirone directions exactly. Ask your doctor or pharmacist for more details if you're interested in using this medication for a different purpose. Your doctor may start you on a low dose of buspirone and gradually increase your dose, not more often than once every 2 to 3 days.

Missed dose

Do not double-up on your medication to make up for a missed dose. If your next scheduled dose is almost due, skip the missed dose. As soon as you remember, take the missed dose.


However, if overdose is suspected, seek emergency medical attention. A buspirone overdose is unlikely to happen if it is given by a healthcare professional in a hospital setting. Call your doctor, the local poison control center, or go to the hospital right away if you take too much buspirone.


This medication should not, however, be flushed down the toilet. Instead, utilizing a medicine take-back program is the best way to get rid of your medication. All medications should be kept out of the sight and reach of children, as many of the containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for small children to open. Store this medication out of children's reach in the tightly closed, original container. If you do not have access to a take-back program, visit the FDA's Safe Disposal of Medicines website at for more details. Store it at room temperature, away from light, excessive heat, and moisture (not in the bathroom). To find out about take-back programs in your area, speak with your pharmacist or the garbage/recycling department in your city. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Always lock safety caps and place the medication in a safe location - one that is up and away and out of their sight and reach.

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Side effects

There could be negative effects from buspirone. If you experience any of these symptoms, call your doctor immediately: dizziness nausea diarrhea headache excitement confusion fatigue nervousness difficulty falling asleep or staying asleep feelings of anger or hostility lightheadedness headache weakness numbness increased sweating rash hives itching swelling of the face, eyes, mouth, throat, tongue, or lips fast or irregular heartbeat blurred vision uncontrollable shaking of a part of the body agitation, fever, sweating, dizziness, flushing, confusion, fast or irregular heartbeat, shivering, severe muscle stiffness or twitching, seizures, hallucinations, loss of coordination, nausea, vomiting, or diarrhea If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088). Dizziness, nausea, diarrhea, headache, excitement, confusion, fatigue, nervousness, trouble sleeping or staying asleep, feelings of rage or hostility, lightheadedness, headache weakness, numbness, increased sweating, rash, hives, itching, swelling of the face, eyes, mouth, throat, tongue, or lips, fast or irregular heartbeat, blurred vision, uncontrollable shaking of a part of the body, agitation, fever, sweating, and a headache.


Ask your doctor before taking buspirone with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. drug interactions with buspirone (more information) More information on buspirone Adverse reactions Drug interactions Dosage guidance During pregnancy or breastfeeding Reviews (1,205) Patient advice Drug images Alternatives pricing & coupons Spanish Drug class: various anxiolytics, sedatives, and hypnotics Resources for patients Advanced Reading Other brands BuSpar, Vanspar Professional resources Prescribing Information Related treatment manuals Sexual dysfunction, SSRI-induced anxiety Borderline Personality Disorder Panic D Other drugs may interact with buspirone, including prescription and over-the-counter medicines, vitamins, and herbal products. These side effects may get worse if you combine this medication with other medications that make you sleepy or slow your breathing. Give a list of all the medications you are currently taking, as well as any that you start or stop taking, to each of your healthcare providers.


Until you are certain of how buspirone affects you, avoid operating machinery or driving a vehicle. If you have an allergy to buspirone or any of its ingredients, do not take buspirone. Buspirone is known to have serious side effects, including changes in cognitive and motor function, skin rash or itching, fast or irregular heartbeat, blurred vision, and unusual movements of the head or neck. Buspirone can also make you feel drowsy and dizzy.

What is buspirone taken for?

Buspirone is used to treat certain anxiety disorders or to relieve the symptoms of anxiety. However, buspirone usually is not used for anxiety or tension caused by the stress of everyday life.

How does buspirone make you feel?

It may help you think more clearly, relax, worry less, and take part in everyday life. It may also help you to feel less jittery and irritable, and may control symptoms such as trouble sleeping, sweating, and pounding heartbeat.

What is the most common side effect of buspirone?

Dizziness, drowsiness, headache, nausea, nervousness, lightheadedness, restlessness, blurred vision, tiredness, and trouble sleeping may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.

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Akshat Bhatnagar Jul 3, 2014, 9:16:23 PM

Effect of buspirone on sexual dysfunction in depressed patients treated with selective serotonin reuptake inhibitors. Primary care companion to the Journal of clinical psychiatry, 4(1), 30. While the effects of Zoloft may begin to show within 2 weeks, its full benefits are realizable within 3 months.

DzianisH Jul 6, 2010, 6:03:02 AM

BuSpar can be taken with food or without, but it must be taken consistently—usually two or three times daily. What other medications can you take for anxiety instead of BuSpar? More severe implications of this combination include problems with muscle control, memory, and breathing. When your doctor decides that you should stop taking BuSpar, the dose will gradually be reduced to help avoid the potential effects of withdrawal.

izb May 27, 2015, 5:34:15 PM

So for Buspirone, the therapeutic class is an anti-anxiety while the pharmacologic class is an Azapirone. Now go out and be your best self today. This is an oral medication, as you can see here in the picture, some Buspar tablets.

SRINIVAS Jun 1, 2011, 11:11:17 AM

Peter Paff May 16, 2017, 9:54:25 AM

Common psychiatric medications prescribed in drug rehab centers for dual diagnosis treatment of benzodiazepine addiction and withdrawal are: Klonopin (Clonazepam) • Klonopin is a long-acting benzodiazepine that can help minimize symptoms of benzodiazepine withdrawal from short-acting benzo addiction. It is estimated that 80% of benzodiazepine abusers are in fact poly-drug users. Buspirone (Buspar) • Buspirone is a medication used to reduce anxiety.

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