Side effects
The usual dosage of aspirin has mild side effects, such as nausea, dyspepsia, gastrointestinal ulceration, and bronchospasm.
Interactions
Antipyretic: Influenza and cold symptoms. Aspirin is recommended for the following conditions: Prophylaxis against arterial occlusive events, including acute ischaemic stroke/TIA, bypass surgery, myocardial infarction, and myocardial re-infarction. Osteoarthritis is a chronic condition characterized by pain and inflammation. Mild to moderate pain includes headaches, backaches, cramps, toothaches, and dysmenorrhea.
Contraindications
Mention any of the following medications: acetazolamide (Diamox); angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perind Before taking aspirin, let your doctor and pharmacist know if you have any allergies to tartrazine dye, aspirin, other painkillers, or fever reducers, as well as a list of all the prescription and over-the-counter medicines, vitamins, dietary supplements, and herbal products you currently use or plan to use. Unless specifically instructed to do so by your doctor, avoid taking aspirin doses greater than 81 mg (e.g., 325 mg) during or after the first 20 weeks of pregnancy. Ask your doctor if you should take aspirin or other painkillers if you drink three or more alcoholic beverages per day. If you become pregnant while taking aspirin or aspirin-containing medications, call your doctor. If you are having surgery, including dental surgery, inform the doctor or dentist that you are taking aspirin. The possibility of experiencing an aspirin allergy reaction increases if you have these conditions. It is safe to take aspirin in low doses up to 81 mg while pregnant, but if taken later in the pregnancy, at 20 weeks or later, it may harm the fetus and interfere with delivery. If you regularly take aspirin to prevent heart attack or stroke, do not take ibuprofen (Advil, Motrin) to treat pain or fever without first consulting your doctor. Your doctor may need to change the doses of your medications or monitor you more closely for side effects. Your doctor may advise against taking aspirin if you frequently experience heartburn, an upset stomach, or stomach pain, have ulcers, anemia, bleeding issues like hemophilia, kidney or liver disease, are pregnant or plan to become pregnant, or are nursing a baby. Inform your doctor if you have or have ever had asthma, frequent stuffy or runny nose, or nasal polyps (growths on the linings of the nose). Your doctor will likely instruct you to wait a while before taking a dose of ibuprofen after taking your daily aspirin.
NICE NG17 2015 (updated December 2020) states “Do not offer aspirin for the primary prevention of cardiovascular disease to adults with type 1 diabetes.” https://www.nice.org.uk/guidance/ng17/resources/type-1-diabetes-in-adults-diagnosis-and-management-pdf-1837276469701 NICE NG28 2015 (updated December 2020) Type 2 diabetes in adults- management state “Do not offer antiplatelet therapy (aspirin or clopidogrel) for adults with type 2 diabetes without cardiovascular disease.” https://www.nice.org.uk/guidance/ng151/resources/user-guide-and-data-sources-pdf-8834927870 Primary prevention of colorectal cancer/all GI cancers NICE NG151 Colorectal cancer guidelines recommend daily aspirin for 2 years or more to help prevent colorectal cancer in people with Lynch syndrome. Poon LC, Shennan A, Hyett JA et al The International federation of Gynaecology and Obstetrics (FIGO) initiative on pre-eclampsia: a pragmatic guide for first-trimester screening and prevention. https://www.nice.org.uk/guidance/ng151/resources/user-guide-and-data-sources-pdf-8834927870 The International Federation of Gynaecology and Obstetrics recommend that women identified as high risk of pre-eclampsia during first trimester screening should be given aspirin prophylaxis (150mg at night from 11-14 weeks gestation until delivery or the diagnosis of pre-eclampsia). @ https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/ijgo.12802 A Cochrane review from 2019 concluded that low dose aspirin does slightly reduce the risk of pre-eclampsia and its complications but that further research is required to identify those most likely to benefit.
However, the salicylic acid in aspirin neutralizes these sweat stains by breaking down the chemical components of sweat. The history of using aspirin to treat skin conditions goes back to the fifth century B.C. Aspirin tablets are used to ease fever, headache, and body pains and aches.
This is a based on a careful appraisal of risks versus benefits of aspirin or other antiplatelet therapy. The purpose of this document is to keep a working list of European guidelines with information on aspirin. https://www.escardio.org/The-ESC/Press-Office/Press-releases/bleeds-and-benefit-with-aspirin-balanced-in-patients-with-diabetes-and-no-effect-on-cancer The 2020 ESC guidelines for the management of acute coronary syndromes, in patients presenting without persistent ST-segment elevation, recommends that people [without atrial fibrillation] undergoing percutaneous coronary intervention are given aspirin, unless contraindicated, at a loading dose of 150-300 mg once daily and a maintenance dose of 75-100 mg once daily. They recommend a P2Y12 receptor inhibitor is given in addition to low-dose aspirin for the first 12 months https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Acute-Coronary-Syndromes-ACS-in-patients-presenting-without-persistent-ST-segm The 2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes recommended aspirin for CVD event prevention at a dose of 75-100 mg daily in patients with previous MI or revascularization.
• • The Information section is compiled using current published information at the time of writing and whilst every effort has been made to avoid errors, professional clinical judgement is required to interpret the information given. • J Am Coll Cardiol.2021;78(20):1987-1989. https://doi.org/10.1016/j.jacc.2021.08.071And Palmerini T, Bruno AG, Redfors B, et al. 3- or 1-month DAPT in patients at high bleeding risk undergoing Everolimus-Eluting Stent implantation.
If pain persists, it is advisable to see a doctor for further advice. Preventing COX from functioning will reduce the production of these chemicals, alleviating pain and inflammation. The effect of preventing blood clots means that aspirin can also increase the chances of surviving a heart attack, as blood clots can block the blood supply to the heart. It blocks the functioning of the enzyme cyclo-oxygenase (COX).