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Arpamyl
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arpamyl

Arpamyl is a calcium channel blocker that eases and widens blood vessels to lower blood pressure.

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Description

Arpamyl also slows the heart's ability to transmit electrical impulses that coordinate contraction by reducing electrical impulse conduction through the heart. As a Ca2+-channel blocker that relaxes (widens) veins and arteries, Arpamyl lessens the workload placed on the heart by facilitating easier pumping. Arpamyl is used to treat angina, hypertension, and some types of irregular heartbeats. When calcium enters the myocytes, it causes the smooth muscles to relax, improving oxygen delivery to the myocardial tissue while lowering total peripheral resistance, systemic blood pressure, and afterload. Calcium also causes the smooth muscles to contract, which is what causes the condition known as a calcium reflex.

Dosage

The recommended dosage is 180–480 mg per day, which can be consumed all at once or in two–three smaller doses. Never go over the dose that was prescribed to you by your doctor. With or without food, take orally.

Missed dose

Simply skip the subsequent dose if it is almost time for your next intake and go back to your regular schedule. As soon as you remember, take the missed dose.

Overdose

It's possible that an overdose is the cause of your slow heartbeat and fainting. If you believe too much Arpamyl was consumed, seek immediate medical attention.

Storage

Store 15-30 C (59-86 F) at room temperature away from light, moisture, pets, and children.

Side effects

Usually, arpamyl is well tolerated. Seek out immediate medical attention if any of the above-mentioned severe side effects occur. Other potential symptoms include rashes, swelling, breathing difficulties, and jaundice. The most frequent adverse reactions are headache, constipation, rash, weakness or fainting, and swelling of the lower extremities.

Interactions

Arpamyl inhibits elimination of alcohol, increases the efficacy of doxorubicin both in tissue culture systems and in patients. Digoxin toxicity can result from the prolonged use of verapamil, which can cause a 50% to 75% rise in serum levels during the first week of treatment. Co-administration of Arpamyl with aspiring in rare cases increases risk of bleeding. When oral antihypertensive medications are administered together, the effects are additive. When using Arpamyl, it's crucial to adjust the digoxin dosage for the patient. Cyclophosphamide, oncovin, procarbazine, prednisone (COPP) and the vindesine, adriamycin, cisplatin (VAC) cytotoxic drug regimens are able to decrease absorption of Arpamyl. Tell your doctor about all of your medications, particularly those that contain lithium, such as Disopyramide, Flecainide, Quinidine, Phenobarbital, and Cyclosporin. Certain liver tests' results could become slightly abnormal if you take this medication.

Contraindications

Arpamyl's drowsiness and dizziness side effects can be made worse by alcohol, while grapefruit interacts with the drug's ingredients. Patients with severe left ventricular dysfunction, hypotension (systolic pressure less than 90 mm Hg) or cardiogenic shock, sick sinus syndrome (except in patients with a functioning artificial ventricular pacemaker), atrioventricular block degree II-III (except in patients with a functioning artificial ventricular pacemaker), atrial flutter or atrial fibrillation, and an accessory bypass trac are contraindicated for the use of apami. Avoid consuming alcoholic beverages, grapefruit juice, and grapefruit. Avoid standing up too quickly after sitting or lying down because you might feel lightheaded.

Target Point Shipping Method Tracking Delivery Time Price
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Worldwide shipping

Registered Mail  Not trackable 14-21 business days USD 20.00 per order
EMS  Trackable, where available 5-9 business days USD 30.00 per order

Delivery time is:

Registered Mail - 14-21 business days, prices - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, prices - USD 30.00, signature is required on delivery.
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