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anastrozole medication use

A competitive, selective, non-steroidal aromatase inhibitor called anastrozole is used as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer.

Other names for this medication:
Arimidex

Similar Products:
Progesterone, Yasmin, Parlodel, Caberlin, Ponstel, Drospirenone, Estrace, Aygestin, Norethisterone, Levonorgestrel, Provera, Cabergoline, Fosamax

Description

Anastrazole inhibits the aromatase enzyme, which is primarily found in the adrenal glands, liver, and fatty tissues, in a selective and competitive manner to produce its anti-estrogenic effects. By competitively inhibiting the biosynthesis of estrogen at these enzymes, anastrozole effectively reduces circulating estrogen levels and, as a result, the development of hormone receptor-positive tumors. In postmenopausal women, estrogen is primarily derived from the conversion of adrenally-produced androgens into estrogens. Many breast cancers are hormone receptor-positive, meaning their growth is stimulated and/or maintained by the presence of hormones such as estrogen or progesterone.

Dosage

The oral tablet form of anastrozole is available. Women who are at a high risk of developing breast cancer may also use anastrozole to stop the disease from occurring. The manufacturer's information for the patient can be obtained by asking your pharmacist or doctor. Continue to take anastrozole even if you feel well. Without consulting your doctor, do not stop taking anastrozole. Take it only as directed by your doctor, neither more nor less than that amount or more frequently. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. It is usually taken once a day with or without food. Take anastrozole at roughly the same time each day. Administer anastrozole exactly as prescribed. When using this medication to treat your condition, discuss the risks with your doctor. Inquire with your doctor or pharmacist for more details if you believe this medication may be prescribed for other purposes. Continue eating normally unless your doctor instructs you otherwise. It's possible that you'll need to use anastrozole for a long time.

Missed dose

To make up for a missed dose, don't take a second one. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. As soon as you realize you missed a dose, take it.

Overdose

If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. To report an overdose, dial 1-800-222-1222 for the poison control hotline. Information is also available online at https://www.poisonhelp.org/help.

Storage

This medication should not, however, be flushed down the toilet. A medicine take-back program is the preferable method for getting rid of your medication. All medications should be kept out of the sight and reach of children, as many containers (such as weekly pill containers and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for small children to open. Keep this medication in the container it came in, tightly closed, and out of reach of children. If you are unable to participate in a take-back program, visit the FDA's Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for more details. It should not be kept in the bathroom. Store it at room temperature, away from sources of extreme heat and moisture. To find out about take-back programs in your area, speak with your pharmacist or the garbage/recycling department in your city. Always lock safety caps and immediately put the medication in a safe place, one that is up and away and out of their sight and reach. http://www.upandaway.org Unused medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.

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Side effects

Hair loss, allergic reactions, nausea, vomiting, drowsiness, and other side effects are frequent ones. Very common side effects: Hot flushes, asthenia, joint stiffness, arthritis, headache, nausea, rash etc.

Interactions

Co-administration with food slows down absorption, but not to the same extent overall. Use whether or not you are eating.

Contraindications

Blood tests for liver function may change as a result of anastrozole-induced liver inflammation. Your bones may become softer and weaker as a result of anastrozole's ability to lower estrogen levels in your body. If you experience any of the following symptoms, seek medical attention right away: facial, oral, or throat swelling difficulty breathing or swallowing liver issues. Serious side effects have been reported with anastrozole including the following: heart disease. If you experience any blisters, ulcers, or skin lesions as a result of a severe allergic reaction, stop taking anastrozole and contact your doctor right away. Do not take anastrozole if you are allergic to any anastrozole ingredient are pregnant, suspect you may be pregnant, or intend to become pregnant have not completed menopause (are premenopausal), are a man or child, are taking any other medication, or have any of the following conditions. If you experience any of these signs or symptoms, stop taking anastrozole and call your doctor right away. In the event that you experience chest pain or breathlessness, stop taking anastrozole and contact your doctor right away. Osteoporosis (the softening and weakening of bones) can cause these symptoms. This can raise your risk of fractures, particularly of the wrist, hip, and spine. Women with early breast cancer who take anastrozole and have a history of heart artery blockages (ischemic heart disease) could slightly increase their risk of developing this type of heart disease in comparison to patients with comparable conditions taking tamoxifen. Your physician might examine you for this. While you are taking anastrozole, your doctor may perform blood tests to check your cholesterol. skin reactions. Before you begin taking anastrozole and as needed throughout treatment with anastrozole, your doctor may prescribe a test for you called a bone mineral density study.

Is anastrozole a form of chemotherapy?

Is anastrozole (Arimidex) a type of chemotherapy? Anastrozole (Arimidex) is considered a hormone therapy rather than a traditional chemotherapy medication. Chemotherapy is used to target and kill cancer cells, whereas anastrozole (Arimidex) is used to lower estrogen in the body.

Will it affect my contraception or fertility?

Anastrozole is generally only given to you if you have gone through the menopause. However, some people find that they start to having periods again after taking anastrozole. If this happens to you, it’s important to use reliable contraception. Talk to your doctor if your periods start again, or if there is any chance that you maybe are pregnant. Anastrozole is not recommended during pregnancy .

What's the cost of anastrozole?

Anastrozole Prices and Coupons The average cost for 30 Tablet(s), 1mg each of the generic (anastrozole) is $183.99. You can buy anastrozole at the discounted price of $10.16 by using the WebMDRx coupon, a savings of 94%. Even if this drug is covered by Medicare or your insurance, we recommend you compare prices.

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Testimonials
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Cole9350 Apr 24, 2018, 10:56:34 PM

This antineoplastic or immunomodulatory drug article is a stub. It underwent clinical testing for evaluation for use as an antineoplastic agent; however it was withdrawn from testing when no difference was detected in the duration of median survival as compared to the progestational agent megestrol acetate and research instead focused on the other third generation aromatase inhibitors anastrozole, letrozole and exemestane. 6-[(4-Chlorophenyl)(1,2,4-triazol-1-yl)methyl]-1-methylbenzotriazole Vorozole (developmental code name R-76713; former tentative brand name Rizivor) is a triazole based competitive inhibitor of the aromatase enzyme.

Springscar Sep 22, 2017, 1:42:38 AM

This meant that there is no estrogen left circulating in the body for the cancer cells to piggyback on. The most commonly used, basic anabolic steroid cycle is Test-E at 500mg/week for 12 weeks. At the end of your cycle, get bloodwork to check your E2 levels. But with all due respect, his form and conditioning on that stage was poor. But in the end, you will be able to narrow down on a dose that lets you stick to the sweet spot that we mentioned above.

Kernel Korn Nov 17, 2012, 4:58:26 PM

Juvise Pharmaceuticals commercializes ARIMIDEX in several countries of Europe, Africa and Middle-East.

Paul Griffiths Nov 4, 2018, 5:11:05 PM

Food decreases the rate of absorption, though this is not considered clinically significant. These patients should be assessed for the risk of osteoporosis before starting therapy, and the decision to treat should be made on an individual basis. Pharmacokinetics Anastrozole is rapidly and almost completely absorbed from the gastrointestinal tract after oral doses, with peak plasma concentrations within about 2 hours. Adverse effects were mild, although most patients had breakthrough bleeding, which exacerbated pain. It is used in the treatment of advanced or locally advanced breast cancer, and as adjuvant treatment in early breast cancer, in postmenopausal women in an oral dose of 1 mg daily.

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