Side effects
Ampicillin side effects (more detail) In the event that you experience: For medical guidance on side effects, contact your doctor. The following are examples of frequent side effects: If you experience any of the warning signs of an allergic reaction (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling), seek emergency medical attention. This is not a complete list of side effects and others may occur. You can contact the FDA to report side effects at 1-800-FDA-1088. nausea, vomiting, stomach pain, diarrhea; rash; swollen, black, or "hairy" tongue; or vaginal itching or discharge. Blisters, ulcers, or soreness in the mouth; skin rash, redness, or itching; fever, chills, sore throat, swollen glands, joint pain, or feeling unwell; pale skin, cold hands and feet; or feeling light-headed or short of breath are all signs of an adverse reaction to this medication.
Interactions
Take this on an empty stomach.
Contraindications
Inform your doctor and pharmacist of all prescription and non-prescription drugs, vitamins, dietary supplements, and herbal products you are currently taking or plan to take. Request an ingredient list from your pharmacist. Make sure to mention any of the following: probenecid (Probalan in Col-Probenecid), oral contraceptives, other antibiotics, and allopurinol (Lopurin, Zyloprim). If you have an allergy to ampicillin, penicillins, cephalosporin antibiotics like cefaclor, cefadroxil, cefazolin (Ancef, Kefzol), cefdinir, cefditoren, cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefpodoxi Call your physician if you become pregnant while taking ampicillin. Inform your doctor if you have mononucleosis (a virus also known as "mono"), have or have ever had allergies, asthma, hives, or hay fever, or kidney disease. Also inform your doctor if you are pregnant, intend to become pregnant, or are nursing.
Some of the side effects may be rare but serious for ampicillin injection. These side effects are possible, but do not always occur for ampicillin injection. Take as directed by your doctor or follow the direction printed on the product insert into ampiccilin box. Anaemia Itching Of Skin Interstitial Nephritis Inflammation Of Large Intestine Life-Threatening Skin Condition Skin Rash Precautions & How to Use Before using this ampicillin injection, inform your doctor about your current list of medications, over the counter products or current medication chart.
If they occur, they are likely to be temporary, and not serious. If you are having blood or urine tests, please tell your doctor that you are taking Ampicillin. Allergy is more common in patients who are allergic to aspirin. infections of the intestines) • Enteric/Typhoid fever (infectious disease contracted by eating food or drinking water contaminated with Salmonella) • Gynaecological infections and Gonorrhoea (a sexually transmitted disease) • Infections of the blood (Septicaemia) • Skin and soft tissue (e.g.
^ DE 2144457, Ekström, Bertil Ake & Sjöberg, Berndt Olof Harald, "α-Aminopenicilline und Verfahren zu deren Herstellung [α-aminopenicillins and processes for their preparation]", published 1972-03-30, assigned to Astra Läkemedel AB ^ Ekstrom BA, Sjoberg BO, U.S. Patent 3,873,521 and U.S. Patent 3,939,270 (1975 and 1976 both to Astra). It is a prodrug of ampicillin with improved oral bioavailability. The relatively small chemical difference between ampicillin and benzylpenicillin not only allows for substantial oral activity but also results in a substantial broadening of antimicrobial spectrum so as to allow for use against many Gram-negative bacteria. An azidopenicillin sodium salt (1) is reacted with mixed carbonate ester 2 (itself prepared from acetaldehyde and ethyl chloroformate) to give ester 3.
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The following adverse reactions have been reported as associated with the use of ampicillin: Gastrointestinal: glositis, stamatitis, nausea, vomiting, enterocolitis, pseudomembranous colitis, and diarrhea. The rash, which usually does not develop within the first week of therapy, may cover the entire body including the soles, palms, and oral mucosa. Liver: Moderate elevation in serum glutamic oxalaacetic transaminase (SGOT) has been noted, but the significance of this finding is unknown.
It inhibits the third and final stage of bacterial cell wall synthesis in binary fission, which ultimately leads to cell lysis. It differs from penicillin only by the presence of an amino group. • Belonging to the penicillin group of beta-lactam antibiotics, ampicillin is able to penetrate Gram-positive and some Gram-negative bacteria.