Side effects
There may be adverse effects from amiodarone. If you experience any strange side effects while taking this medication, call your doctor right away. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). If you experience any of the following symptoms, or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment: constipation loss of appetite headache decreased sex drive difficulty falling asleep or staying asleep flushing changes in ability to taste and smell changes in amount of saliva rash weight loss or gain restlessness weakness nervousness irritability intolerance to heat or cold thinning hair excessive sweating changes in menstrual cycle swelling in the front of the neck (goiter) swelling of the hands, feet, ankles, or lower legs uncontrollable shaking of a part of the body decreased concentration movements that you cannot control poor coordination or trouble walking numbness or tingling in the hands, legs, and feet muscle weakness Amiodarone may cause other side effects. Inform your doctor if any of these symptoms persist or are severe, including: decreased sex drive, difficulty sleeping, flushing, changes in taste and smell, rash, weight gain or loss, weakness, nervousness, irritability, intolerance to heat or cold, thinning hair, goiter, swelling of the hands, constipation, loss of appetite, headache, changes in amount of saliva, restlessness, and nervousness.
Interactions
Steer clear of St. Products containing grapefruit should be avoided. As CYP3A4 metabolism is inhibited by grapefruit, the serum concentration of amiodarone may rise. John's Wort. Take with or without food. Food has no impact on the absorption. As a result, it might lessen the serum concentration and effectiveness of amiodarone. This plant stimulates amiodarone's CYP3A4 metabolism.
Contraindications
Inform your doctor and pharmacist about all prescription and non-prescription drugs, vitamins, and dietary supplements you are taking or plan to take. If you have an allergy to amiodarone, iodine, any other medications, or any of the ingredients in amiodarone tablets, tell your doctor and pharmacist before taking amiodarone.
This medication along these lines forestalls genuine medical conditions that can here and there be lethal and decreases your danger of death. It is regularly possibly given by infusion in a clinic when a quick reaction is required or when tablets have not worked or can’t be given. It is an enemy of arrhythmic sort of medication which quickly reestablishes your heart to a consistent and standard musicality.
They’ll ultimately prescribe the smallest dosage that provides the desired effect. The safety and effectiveness of amiodarone have not been established in people under the age of 18 years. This is usually 400 mg per day taken by mouth in a single dose or separated doses.
In some cases, this inflammation can progress to more serious thickening or scarring (fibrosis), which can be life-threatening. Amiodarone interacts with many medications, and advice in the relevant section of the Summary of Product Characteristics (SmPC) should be strictly followed. The MHRA has received a report from a Coroner following the death by multi-organ failure of a woman who had been treated with amiodarone for approximately 5 years and who developed pneumonia during treatment.
Organs of view: the deposition of lipofuscin in the corneal epithelium Dermatological reactions: may appear weak pigmentation in open areas of skin Endocrine status: with long-term intake in rare cases may develop hypothyroidism Cardiovascular system: the application of high doses of Cordarone, as well as in susceptible patients, may cause bradycardia, AV conduction delay, arterial hypotension Gastrointestinal tract and liver: rarely nausea, heaviness in the epigastrium, the violation of liver function Tablets. Repeated injections need to be performed no earlier than 15 minutes after the first injection. Cordarone increases the refractory period and reduces the excitability of the myocardium. Hypersensitivity to iodine and / or amiodarone Sick sinus syndrome (sinus bradycardia, sinoatrial block) Violations of atrioventricular and intraventricular conduction Thyroid dysfunction (hypothyroidism, gipertirez) Hypokalemia, cardiac failure (decompensation stage) Pregnancy The period of lactation Children age (18 years) (efficacy and safety are not established) Simultaneous treatment with MAO inhibitors Interstitial lung disease Solution for injection. Brand names: Amiodarone, Alti-Amiodarone; Amiodarone Hydrochloride for Injection; Apo-Amiodarone; Dom-Amiodarone; Gen-Amiodarone; Novo-Amiodarone; PHL-Amiodarone; PMS-Amiodarone; Ratio-Amiodarone; Ratio-Amiodarone I.V.
======= • RETURNS ======= If a product does not meet your specifications, you may return the item in its original packaging, in resalable condition, within 30 days for a full credit. • Returned merchandise must be sent freight prepaid and be received in new, resalable condition. If a damaged shipment is received, please note the extent of the damage to the carrier at the time of delivery.
Amiodarone is classified under class III drugs based on the Vaughan Williams Classes under antiarrhythmic medication. The drug amiodarone was first discovered in 1961 by a Belgian company to treat angina (chest pain or discomfort) and is widely used in South America and Europe. There are a total of 4-classes under Vaughan Williams Classes- Class I drugs are sodium channel blockers.
• South India : Kerala, Karnataka ,Tamil Nadu,Andhra Pradesh. POSSIBLE SIDE EFFECTS Like all medicines, CADRONAX can cause side effects, although not everybody gets them. • The other ingredients are lactose monohydrate, maize starch, povidone K90, silica, colloidal anhydrous, pregelatinised starch and magnesium stearate.